Antigenic peptide trimming by ER aminopeptidases-Insights from structural studies

Molecular Immunology

Volumn 55, Issue 3-4, 2013, Pages 212-219

  Stratikos, Efstratios ^a   Stern, Lawrence J ^b  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Aminopeptidase; Antigen processing; Enzyme; Mechanism; Peptide; Polymorphism; Structure; X ray crystallography

Indexed keywords

AMINOPEPTIDASE; CYSTYL AMINOPEPTIDASE; ERAP1 PROTEIN; ERAP2 PROTEIN; HETERODIMER; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTATION; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR HISTOCOMPATIBILITY COMPLEX; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PSORIASIS; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ACTIVITY RELATION;

ADAPTIVE IMMUNITY; AMINOPEPTIDASES; ANIMALS; ANTIGENS; ENDOPLASMIC RETICULUM; HUMANS; MODELS, MOLECULAR; PEPTIDE FRAGMENTS;

EID: 84877596051     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2013.03.002     Document Type: Review

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