Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits

Biological Psychiatry

Volumn 73, Issue 11, 2013, Pages 1045-1053

  Sripada, Rebecca K ^a,b   Marx, Christine E ^d,e   King, Anthony P ^a,c   Rampton, Jessica C ^b   Ho, S Shaun ^a   Liberzon, Israel ^a,b,c  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e DURHAM VA MEDICAL CENTER   (United States)

Author keywords

Allopregnanolone; anxiety; emotion regulation; fMRI; neuroactive steroid; pharmaco fMRI; pregnenolone

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; NEUROSTEROID; PREGNENOLONE;

AMYGDALOID NUCLEUS; ANXIETY; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; EMOTIONALITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; INSULA; MALE; NERVE CELL NETWORK; NEUROIMAGING; NORMAL HUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; SELF REPORT; TASK PERFORMANCE;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ATTENTION; BRAIN; BRAIN MAPPING; CASE-CONTROL STUDIES; EMOTIONS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; PREGNANOLONE; PREGNENOLONE; REACTION TIME; TIME FACTORS; YOUNG ADULT;

EID: 84877585241     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.12.008     Document Type: Article

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