메뉴 건너뛰기




Volumn 87, Issue 10, 2013, Pages 5732-5745

Tat exon 1 exhibits functional diversity during HIV-1 subtype C primary infection

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; TRANSACTIVATOR PROTEIN; VIRUS RNA;

EID: 84877353853     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03297-12     Document Type: Article
Times cited : (12)

References (98)
  • 1
    • 84877318160 scopus 로고    scopus 로고
    • Report on the global AIDS epidemic. Joint United Nations Programme on HIV/ AIDS (UNAIDS)
    • United Nations Programme on HIV/AIDS (UNAIDS), Geneva, Switzerland.
    • United Nations Programme on HIV/AIDS (UNAIDS). 2011. Report on the global AIDS epidemic. Joint United Nations Programme on HIV/ AIDS (UNAIDS), Geneva, Switzerland.
    • (2011)
  • 3
    • 55249126405 scopus 로고    scopus 로고
    • Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression
    • Modjarrad K, Chamot E, Vermund SH. 2008. Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression. AIDS 22:2179-2185.
    • (2008) AIDS , vol.22 , pp. 2179-2185
    • Modjarrad, K.1    Chamot, E.2    Vermund, S.H.3
  • 4
    • 73149083473 scopus 로고    scopus 로고
    • Functions of Tat: the versatile protein of human immunodeficiency virus type 1
    • Romani B, Engelbrecht S, Glashoff RH. 2010. Functions of Tat: the versatile protein of human immunodeficiency virus type 1. J. Gen. Virol. 91:1-12.
    • (2010) J. Gen. Virol. , vol.91 , pp. 1-12
    • Romani, B.1    Engelbrecht, S.2    Glashoff, R.H.3
  • 5
    • 20444422574 scopus 로고    scopus 로고
    • Mechanisms for HIV Tat upregulation of IL-10 and other cytokine expression: kinase signaling and PKR-mediated immune response
    • Li JC, Lee DC, Cheung BK, Lau AS. 2005. Mechanisms for HIV Tat upregulation of IL-10 and other cytokine expression: kinase signaling and PKR-mediated immune response. FEBS Lett. 579:3055-3062.
    • (2005) FEBS Lett. , vol.579 , pp. 3055-3062
    • Li, J.C.1    Lee, D.C.2    Cheung, B.K.3    Lau, A.S.4
  • 7
    • 22844450207 scopus 로고    scopus 로고
    • Extracellular HIV Tat and Tat cysteine rich peptide increase CCR5 expression in monocytes
    • Zheng L, Yang YD, Lu GC, Salvato MS. 2005. Extracellular HIV Tat and Tat cysteine rich peptide increase CCR5 expression in monocytes. J. Zhejiang Univ. Sci. B 6:668-672.
    • (2005) J. Zhejiang Univ. Sci. B , vol.6 , pp. 668-672
    • Zheng, L.1    Yang, Y.D.2    Lu, G.C.3    Salvato, M.S.4
  • 8
    • 79960380793 scopus 로고    scopus 로고
    • Negative regulation of HIV-1 transcription by a heterodimeric NFkappaB1/ p50 and C-terminally truncated STAT5 complex
    • Della Chiara G, Crotti A, Liboi E, Giacca M, Poli G, Lusic M. 2011. Negative regulation of HIV-1 transcription by a heterodimeric NFkappaB1/ p50 and C-terminally truncated STAT5 complex. J. Mol. Biol. 410:933-943.
    • (2011) J. Mol. Biol. , vol.410 , pp. 933-943
    • Della Chiara, G.1    Crotti, A.2    Liboi, E.3    Giacca, M.4    Poli, G.5    Lusic, M.6
  • 10
    • 30444431914 scopus 로고    scopus 로고
    • NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
    • Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. 2006. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 25:139-149.
    • (2006) EMBO J. , vol.25 , pp. 139-149
    • Williams, S.A.1    Chen, L.F.2    Kwon, H.3    Ruiz-Jarabo, C.M.4    Verdin, E.5    Greene, W.C.6
  • 11
    • 0023876147 scopus 로고
    • HIV-1 tat trans-activation requires the loop sequence within tar
    • Feng S, Holland EC. 1988. HIV-1 tat trans-activation requires the loop sequence within tar. Nature 334:165-167.
    • (1988) Nature , vol.334 , pp. 165-167
    • Feng, S.1    Holland, E.C.2
  • 12
    • 0032548918 scopus 로고    scopus 로고
    • A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
    • Wei P, Garber ME, Fang SM, Fischer WH, Jones KA. 1998. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92:451-462.
    • (1998) Cell , vol.92 , pp. 451-462
    • Wei, P.1    Garber, M.E.2    Fang, S.M.3    Fischer, W.H.4    Jones, K.A.5
  • 13
    • 0034715791 scopus 로고    scopus 로고
    • Acetylation of HIV-1 Tat by CBP/ P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones
    • Deng L, de la Fuente C, Fu P, Wang L, Donnelly R, Wade JD, Lambert P, Li H, Lee CG, Kashanchi F. 2000. Acetylation of HIV-1 Tat by CBP/ P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. Virology 277:278-295.
    • (2000) Virology , vol.277 , pp. 278-295
    • Deng, L.1    de la Fuente, C.2    Fu, P.3    Wang, L.4    Donnelly, R.5    Wade, JD.6    Lambert, P.7    Li, H.8    Lee, C.G.9    Kashanchi, F.10
  • 15
    • 0031690395 scopus 로고    scopus 로고
    • Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein
    • Hottiger MO, Nabel GJ. 1998. Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein. J. Virol. 72:8252-8256.
    • (1998) J. Virol. , vol.72 , pp. 8252-8256
    • Hottiger, M.O.1    Nabel, G.J.2
  • 16
    • 0032506242 scopus 로고    scopus 로고
    • HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter
    • Marzio G, Tyagi M, Gutierrez MI, Giacca M. 1998. HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter. Proc. Natl. Acad. Sci. U. S. A. 95:13519-13524.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 13519-13524
    • Marzio, G.1    Tyagi, M.2    Gutierrez, M.I.3    Giacca, M.4
  • 20
    • 33749234198 scopus 로고    scopus 로고
    • The yin and yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation
    • Zhou Q, Yik JH. 2006. The yin and yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation. Microbiol. Mol. Biol. Rev. 70:646-659.
    • (2006) Microbiol. Mol. Biol. Rev. , vol.70 , pp. 646-659
    • Zhou, Q.1    Yik, J.H.2
  • 21
    • 0032775261 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR
    • Demarchi F, Gutierrez MI, Giacca M. 1999. Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR. J. Virol. 73:7080-7086.
    • (1999) J. Virol. , vol.73 , pp. 7080-7086
    • Demarchi, F.1    Gutierrez, M.I.2    Giacca, M.3
  • 22
    • 33744804251 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat prevents dephosphorylation of Sp1 by TCF-4 in astrocytes
    • Rossi A, Mukerjee R, Ferrante P, Khalili K, Amini S, Sawaya BE. 2006. Human immunodeficiency virus type 1 Tat prevents dephosphorylation of Sp1 by TCF-4 in astrocytes. J. Gen. Virol. 87:1613-1623.
    • (2006) J. Gen. Virol. , vol.87 , pp. 1613-1623
    • Rossi, A.1    Mukerjee, R.2    Ferrante, P.3    Khalili, K.4    Amini, S.5    Sawaya, B.E.6
  • 23
    • 0036343111 scopus 로고    scopus 로고
    • Differential regulation of HIV-1 cladespecific B, C, and E long terminal repeats by NF-kappaB and the Tat transactivator
    • Roof P, Ricci M, Genin P, Montano MA, Essex M, Wainberg MA, Gatignol A, Hiscott J. 2002. Differential regulation of HIV-1 cladespecific B, C, and E long terminal repeats by NF-kappaB and the Tat transactivator. Virology 296:77-83.
    • (2002) Virology , vol.296 , pp. 77-83
    • Roof, P.1    Ricci, M.2    Genin, P.3    Montano, M.A.4    Essex, M.5    Wainberg, M.A.6    Gatignol, A.7    Hiscott, J.8
  • 25
    • 0033978536 scopus 로고    scopus 로고
    • Elevated tumor necrosis factor-alpha activation of human immunodeficiency virus type 1 subtype C in Southern Africa is associated with an NF-kappaB enhancer gain-of-function
    • Montano MA, Nixon CP, Ndung'u T, Bussmann H, Novitsky VA, Dickman D, Essex M. 2000. Elevated tumor necrosis factor-alpha activation of human immunodeficiency virus type 1 subtype C in Southern Africa is associated with an NF-kappaB enhancer gain-of-function. J. Infect. Dis. 181:76-81.
    • (2000) J. Infect. Dis. , vol.181 , pp. 76-81
    • Montano, M.A.1    Nixon, C.P.2    Ndung'u, T.3    Bussmann, H.4    Novitsky, V.A.5    Dickman, D.6    Essex, M.7
  • 26
    • 0030793813 scopus 로고    scopus 로고
    • Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypes
    • Montano MA, Novitsky VA, Blackard JT, Cho NL, Katzenstein DA, Essex M. 1997. Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypes. J. Virol. 71:8657-8665.
    • (1997) J. Virol. , vol.71 , pp. 8657-8665
    • Montano, M.A.1    Novitsky, V.A.2    Blackard, J.T.3    Cho, N.L.4    Katzenstein, D.A.5    Essex, M.6
  • 27
    • 1842614352 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner
    • van Opijnen T, Jeeninga RE, Boerlijst MC, Pollakis GP, Zetterberg V, Salminen M, Berkhout B. 2004. Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner. J. Virol. 78:3675-3683.
    • (2004) J. Virol. , vol.78 , pp. 3675-3683
    • van Opijnen, T.1    Jeeninga, R.E.2    Boerlijst, M.C.3    Pollakis, G.P.4    Zetterberg, V.5    Salminen, M.6    Berkhout, B.7
  • 29
    • 82355165820 scopus 로고    scopus 로고
    • Amino acid sequence divergence of Tat protein (exon1) of subtype B and C HIV-1 strains: does it have implications for vaccine development?
    • Kandathil AJ, Kannangai R, Abraham OC, Pulimood SA, Sridharan G. 2009. Amino acid sequence divergence of Tat protein (exon1) of subtype B and C HIV-1 strains: does it have implications for vaccine development? Bioinformation 4:237-241.
    • (2009) Bioinformation , vol.4 , pp. 237-241
    • Kandathil, A.J.1    Kannangai, R.2    Abraham, O.C.3    Pulimood, S.A.4    Sridharan, G.5
  • 30
    • 84865527007 scopus 로고    scopus 로고
    • Genetic characterization of HIV type 1 Tat exon 1 from a Southern Indian clinical cohort: identification of unique epidemiological signature residues
    • Neogi U, Gupta S, Sahoo PN, Shet A, Rao SD, Ranga U, Prasad VR. 2012. Genetic characterization of HIV type 1 Tat exon 1 from a Southern Indian clinical cohort: identification of unique epidemiological signature residues. AIDS Res. Hum. Retroviruses 28:1152-1156.
    • (2012) AIDS Res. Hum. Retroviruses , vol.28 , pp. 1152-1156
    • Neogi, U.1    Gupta, S.2    Sahoo, P.N.3    Shet, A.4    Rao, S.D.5    Ranga, U.6    Prasad, V.R.7
  • 32
    • 0025735965 scopus 로고
    • Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection
    • Daar ES, Moudgil T, Meyer RD, Ho DD. 1991. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. N. Engl. J. Med. 324:961-964.
    • (1991) N. Engl. J. Med. , vol.324 , pp. 961-964
    • Daar, E.S.1    Moudgil, T.2    Meyer, R.D.3    Ho, D.D.4
  • 35
    • 85027958165 scopus 로고    scopus 로고
    • Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection
    • Novitsky V, Ndung'u T, Wang R, Bussmann H, Chonco F, Makhema J, De Gruttola V, Walker BD, Essex M. 2011. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS 25:1515-1522.
    • (2011) AIDS , vol.25 , pp. 1515-1522
    • Novitsky, V.1    Ndung'u, T.2    Wang, R.3    Bussmann, H.4    Chonco, F.5    Makhema, J.6    De Gruttola, V.7    Walker, B.D.8    Essex, M.9
  • 40
    • 67649537643 scopus 로고    scopus 로고
    • What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?
    • doi:10.1186/1742-4690-6-50
    • Campbell GR, Loret EP. 2009. What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine? Retrovirology 6:50. doi:10.1186/1742-4690-6-50.
    • (2009) Retrovirology , vol.6 , pp. 50
    • Campbell, G.R.1    Loret, E.P.2
  • 41
    • 68449095630 scopus 로고    scopus 로고
    • The HIV hide and seek game: an immunogenomic analysis of the HIV epitope repertoire
    • Vider-Shalit T, Almani M, Sarid R, Louzoun Y. 2009. The HIV hide and seek game: an immunogenomic analysis of the HIV epitope repertoire. AIDS 23:1311-1318.
    • (2009) AIDS , vol.23 , pp. 1311-1318
    • Vider-Shalit, T.1    Almani, M.2    Sarid, R.3    Louzoun, Y.4
  • 50
    • 84860734162 scopus 로고    scopus 로고
    • Viral diversity and diversification of major non-structural genes vif, vpr, vpu, tat exon 1 and rev exon 1 during primary HIV-1 subtype C infection
    • doi:10.1371/journal.pone.0035491.
    • Rossenkhan R, Novitsky V, Sebunya TK, Musonda R, Gashe BA, Essex M. 2011. Viral diversity and diversification of major non-structural genes vif, vpr, vpu, tat exon 1 and rev exon 1 during primary HIV-1 subtype C infection. PLoS One 7:e35491. doi:10.1371/journal.pone.0035491.
    • (2011) PLoS One , vol.7
    • Rossenkhan, R.1    Novitsky, V.2    Sebunya, T.K.3    Musonda, R.4    Gashe, B.A.5    Essex, M.6
  • 52
    • 45849154165 scopus 로고    scopus 로고
    • jModelTest: phylogenetic model averaging
    • Posada D. 2008. jModelTest: phylogenetic model averaging. Mol. Biol. Evol. 25:1253-1256.
    • (2008) Mol. Biol. Evol. , vol.25 , pp. 1253-1256
    • Posada, D.1
  • 53
    • 0242578620 scopus 로고    scopus 로고
    • A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood
    • Guindon S, Gascuel O. 2003. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst. Biol. 52:696-704.
    • (2003) Syst. Biol. , vol.52 , pp. 696-704
    • Guindon, S.1    Gascuel, O.2
  • 54
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. 2011. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28:2731-2739.
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 56
  • 58
    • 0022376704 scopus 로고
    • Dating of the human-ape splitting by a molecular clock of mitochondrial DNA
    • Hasegawa M, Kishino H, Yano T. 1985. Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. J. Mol. Evol. 22:160-174.
    • (1985) J. Mol. Evol. , vol.22 , pp. 160-174
    • Hasegawa, M.1    Kishino, H.2    Yano, T.3
  • 59
    • 0028024626 scopus 로고
    • A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome
    • Muse SV, Gaut BS. 1994. A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome. Mol. Biol. Evol. 11:715-724.
    • (1994) Mol. Biol. Evol. , vol.11 , pp. 715-724
    • Muse, S.V.1    Gaut, B.S.2
  • 63
    • 34547653712 scopus 로고    scopus 로고
    • Leveraging information across HLA alleles/supertypes improves epitope prediction
    • Heckerman D, Kadie C, Listgarten J. 2007. Leveraging information across HLA alleles/supertypes improves epitope prediction. J. Comput. Biol. 14:736-746.
    • (2007) J. Comput. Biol. , vol.14 , pp. 736-746
    • Heckerman, D.1    Kadie, C.2    Listgarten, J.3
  • 64
    • 0033856458 scopus 로고    scopus 로고
    • Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
    • Derdeyn CA, Decker JM, Sfakianos JN, Wu X, O'Brien WA, Ratner L, Kappes JC, Shaw GM, Hunter E. 2000. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J. Virol. 74:8358-8367.
    • (2000) J. Virol. , vol.74 , pp. 8358-8367
    • Derdeyn, C.A.1    Decker, J.M.2    Sfakianos, J.N.3    Wu, X.4    O'Brien, W.A.5    Ratner, L.6    Kappes, J.C.7    Shaw, G.M.8    Hunter, E.9
  • 65
    • 67749110262 scopus 로고    scopus 로고
    • Evidence that ecotropic murine leukemia virus contamination in TZM-bl cells does not affect the outcome of neutralizing antibody assays with human immunodeficiency virus type 1
    • Platt EJ, Bilska M, Kozak SL, Kabat D, Montefiori DC. 2009. Evidence that ecotropic murine leukemia virus contamination in TZM-bl cells does not affect the outcome of neutralizing antibody assays with human immunodeficiency virus type 1. J. Virol. 83:8289-8292.
    • (2009) J. Virol. , vol.83 , pp. 8289-8292
    • Platt, E.J.1    Bilska, M.2    Kozak, S.L.3    Kabat, D.4    Montefiori, D.C.5
  • 66
    • 0031954686 scopus 로고    scopus 로고
    • Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1
    • Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D. 1998. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J. Virol. 72: 2855-2864.
    • (1998) J. Virol. , vol.72 , pp. 2855-2864
    • Platt, E.J.1    Wehrly, K.2    Kuhmann, S.E.3    Chesebro, B.4    Kabat, D.5
  • 67
    • 57349139455 scopus 로고    scopus 로고
    • Identification of gammaretroviruses constitutively released from cell lines used for human immunodeficiency virus research
    • Takeuchi Y, McClure MO, Pizzato M. 2008. Identification of gammaretroviruses constitutively released from cell lines used for human immunodeficiency virus research. J. Virol. 82:12585-12588.
    • (2008) J. Virol. , vol.82 , pp. 12585-12588
    • Takeuchi, Y.1    McClure, M.O.2    Pizzato, M.3
  • 70
    • 0001677717 scopus 로고
    • Controlling false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. 1995. Controlling false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. 57:289-300.
    • (1995) J. R. Stat. Soc. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 72
    • 84858065741 scopus 로고    scopus 로고
    • Mutual information analysis reveals coevolving residues in Tat that compensate for two distinct functions in HIV-1 gene expression
    • Dey SS, Xue Y, Joachimiak MP, Friedland GD, Burnett JC, Zhou Q, Arkin AP, Schaffer DV. 2012. Mutual information analysis reveals coevolving residues in Tat that compensate for two distinct functions in HIV-1 gene expression. J. Biol. Chem. 287:7945-7955.
    • (2012) J. Biol. Chem. , vol.287 , pp. 7945-7955
    • Dey, S.S.1    Xue, Y.2    Joachimiak, M.P.3    Friedland, G.D.4    Burnett, J.C.5    Zhou, Q.6    Arkin, A.P.7    Schaffer, D.V.8
  • 75
  • 78
    • 34247158278 scopus 로고    scopus 로고
    • Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat interactions with both cyclin T1 and the Tat transactivation region
    • Xie B, Invernizzi CF, Richard S, Wainberg MA. 2007. Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat interactions with both cyclin T1 and the Tat transactivation region. J. Virol. 81:4226-4234.
    • (2007) J. Virol. , vol.81 , pp. 4226-4234
    • Xie, B.1    Invernizzi, C.F.2    Richard, S.3    Wainberg, M.A.4
  • 81
    • 18144367709 scopus 로고    scopus 로고
    • Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
    • doi:10.1186/1743-422X-2-17.
    • Endo-Munoz L, Warby T, Harrich D, McMillan NA. 2005. Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription. Virol. J. 2:17. doi:10.1186/1743-422X-2-17.
    • (2005) Virol. J. , vol.2 , pp. 17
    • Endo-Munoz, L.1    Warby, T.2    Harrich, D.3    McMillan, N.A.4
  • 82
    • 0025240436 scopus 로고
    • Mutational analysis of the conserved cysteinerich region of the human immunodeficiency virus type 1 Tat protein
    • Rice AP, Carlotti F. 1990. Mutational analysis of the conserved cysteinerich region of the human immunodeficiency virus type 1 Tat protein. J. Virol. 64:1864-1868.
    • (1990) J. Virol. , vol.64 , pp. 1864-1868
    • Rice, A.P.1    Carlotti, F.2
  • 84
    • 77953309482 scopus 로고    scopus 로고
    • Differential induction of interleukin-10 in monocytes by HIV-1 clade B and clade C Tat proteins
    • Wong JK, Campbell GR, Spector SA. 2010. Differential induction of interleukin-10 in monocytes by HIV-1 clade B and clade C Tat proteins. J. Biol. Chem. 285:18319-18325.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18319-18325
    • Wong, J.K.1    Campbell, G.R.2    Spector, S.A.3
  • 85
    • 0028303171 scopus 로고
    • Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1
    • Amendt BA, Hesslein D, Chang LJ, Stoltzfus CM. 1994. Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1. Mol. Cell. Biol. 14:3960-3970.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3960-3970
    • Amendt, B.A.1    Hesslein, D.2    Chang, L.J.3    Stoltzfus, C.M.4
  • 86
    • 0029025083 scopus 로고
    • Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors
    • Amendt BA, Si ZH, Stoltzfus CM. 1995. Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors. Mol. Cell. Biol. 15:4606-4615.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4606-4615
    • Amendt, B.A.1    Si, Z.H.2    Stoltzfus, C.M.3
  • 87
    • 0035798607 scopus 로고    scopus 로고
    • A second exon splicing silencer within human immunodeficiency virus type 1 tat exon 2 represses splicing of Tat mRNA and binds protein hnRNP H
    • Jacquenet S, Mereau A, Bilodeau PS, Damier L, Stoltzfus CM, Branlant C. 2001. A second exon splicing silencer within human immunodeficiency virus type 1 tat exon 2 represses splicing of Tat mRNA and binds protein hnRNP H. J. Biol. Chem. 276:40464-40475.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40464-40475
    • Jacquenet, S.1    Mereau, A.2    Bilodeau, P.S.3    Damier, L.4    Stoltzfus, C.M.5    Branlant, C.6
  • 88
    • 0031052029 scopus 로고    scopus 로고
    • Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells
    • Ma M, Nath A. 1997. Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells. J. Virol. 71:2495-2499.
    • (1997) J. Virol. , vol.71 , pp. 2495-2499
    • Ma, M.1    Nath, A.2
  • 89
    • 0033566297 scopus 로고    scopus 로고
    • The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor
    • Barillari G, Sgadari C, Fiorelli V, Samaniego F, Colombini S, Manzari V, Modesti A, Nair BC, Cafaro A, Sturzl M, Ensoli B. 1999. The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor. Blood 94:663-672.
    • (1999) Blood , vol.94 , pp. 663-672
    • Barillari, G.1    Sgadari, C.2    Fiorelli, V.3    Samaniego, F.4    Colombini, S.5    Manzari, V.6    Modesti, A.7    Nair, B.C.8    Cafaro, A.9    Sturzl, M.10    Ensoli, B.11
  • 90
    • 0033555401 scopus 로고    scopus 로고
    • IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis
    • Fiorelli V, Barillari G, Toschi E, Sgadari C, Monini P, Sturzl M, Ensoli B. 1999. IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis. J. Immunol. 162:1165-1170.
    • (1999) J. Immunol. , vol.162 , pp. 1165-1170
    • Fiorelli, V.1    Barillari, G.2    Toschi, E.3    Sgadari, C.4    Monini, P.5    Sturzl, M.6    Ensoli, B.7
  • 91
    • 43349095840 scopus 로고    scopus 로고
    • NF-kappaB-dependent control of HIV-1 transcription by the second coding exon of Tat in T cells
    • Mahlknecht U, Dichamp I, Varin A, Van Lint C, Herbein G. 2008. NF-kappaB-dependent control of HIV-1 transcription by the second coding exon of Tat in T cells. J. Leukoc. Biol. 83:718-727.
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 718-727
    • Mahlknecht, U.1    Dichamp, I.2    Varin, A.3    Van Lint, C.4    Herbein, G.5
  • 92
    • 0242342409 scopus 로고    scopus 로고
    • An in vivo replicationimportant function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection
    • Smith SM, Pentlicky S, Klase Z, Singh M, Neuveut C, Lu CY, Reitz MS, Jr, Yarchoan R, Marx PA, Jeang KT. 2003. An in vivo replicationimportant function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection. J. Biol. Chem. 278: 44816-44825.
    • (2003) J. Biol. Chem. , vol.278 , pp. 44816-44825
    • Smith, S.M.1    Pentlicky, S.2    Klase, Z.3    Singh, M.4    Neuveut, C.5    Lu, C.Y.6    Reitz Jr., M.S.7    Yarchoan, R.8    Marx, P.A.9    Jeang, K.T.10
  • 94
    • 44649123290 scopus 로고    scopus 로고
    • Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV
    • De Groot AS, Rivera DS, McMurry JA, Buus S, Martin W. 2008. Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV. Vaccine 26:3059-3071.
    • (2008) Vaccine , vol.26 , pp. 3059-3071
    • De Groot, A.S.1    Rivera, D.S.2    McMurry, J.A.3    Buus, S.4    Martin, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.