Effects of HIV-1 Tat on expression of HLA class I molecules

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 11, Issue 3, 1996, Pages 233-240

  Matsui, Masanori ^a   Warburton, Robert J ^a   Cogswell, Patricia C ^a   Baldwin Jr , Albert S ^a   Frelinger, Jeffrey A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

HIV 1; Immunosuppression; MHC class I molecule; Tat

Indexed keywords

CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; N ACETYL BETA GLUCOSAMINIDASE; TRANSACTIVATOR PROTEIN;

ARTICLE; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HLA SYSTEM; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE DEFICIENCY; NORTHERN BLOTTING; PRIORITY JOURNAL; VIRUS REPLICATION;

EID: 0029963033     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199603010-00003     Document Type: Article

References (35)

1. McMichael AJ. Role of class I molecules of the major histocompatibility complex in cytotoxic T-cell function in health and disease. Springer Semin Immunopathol 1992;14:1-16.
2. Townsend A, Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Ann Rev Immunol 1989;7:601-24.
3. + T lymphocytes of patients with AIDS maintain normal broad cytolytic function despite the loss of human immunodeficiency virus-specific cytotoxicity. Proc Natl Acad Sci USA 1990;87:4818-22.
4. Carmichael A, Jin X, Sissons P, Borysiewicz L. Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease. J Exp Med 1993;177:249-56.
5. Shearer GM, Bernstein DC, Tung KSK, et al. A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS). J Immunol 1986;137:2514-21.
6. Rook AH, Masur H, Lane C, et al. Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the ac- quired immune deficiency syndrome. J Infect Dis 1983;72:398-403.
7. Sharma B, Gupta S. Antigen-specific primary cytotoxic T lymphocyte (CTL) responses in acquired immune deficiency syndrome (AIDS) and AIDS-related complexes (ARC). Clin Exp Immunol 1985;62:296-303.
8. Gruters RA, Terpstra FG, De Jong R, Van Noesel CJM, Van Lier RAW, Miedema F. Selective loss of T cell functions in different stages of HIV infection. Eur J Immunol 1990;20:1039-44.
9. Phillips RE, Rowland-Jones S, Nixon DF, et al. Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 1991;354:453-9.
10. Maudsley DJ, Pound JD. Modulation of MHC antigen expression by viruses and oncogenes. Immunol Today 1991;12:429-31.
11. + T cell line, CEM-E5, after HIV-1 infection. J Immunol 1989;143:2858-66.
12. Howcroft TK, Strebel K, Martin MA, Singer DS. Repression of MHC class I gene promoter activity by two-exon Tat of HIV. Science 1993;260:1320-22.
13. Fisher AG, Feinberg MB, Josephs SF, et al. The transactivator gene of HTLV-III is essential for virus replication. Nature 1986;320:367-71.
14. Viscidi RP, Mayur K, Lederman HM, Frankel AD. Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1. Science 1989;246:1606-8.
15. Meyaard L, Otto SA, Schuitemaker H, Miedema F. Effects of HIV-Tat protein on human T cell proliferation. Eur J Immunol 1992;22:2729-32.
16. Arya SK, Guo C, Josephs SF, Wong-Staal F. Transactivator gene of human T-lymphotropic virus type II (HTLV-III). Science 1986;229:69-73.
17. Scharf SJ, Horn GT, Erlich HA. Direct cloning and sequence analysis of enzymatically amplified genomic sequences. Science 1986;233:1076-8.
18. Salter RD, Howell DN, Cresswell P. Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. Immunogenetics 1985;21:235-46.
19. Hauber J, Malim MH, Cullen BR. Mutational analyses of the conserved basic domain of human immunodeficiency virus tat protein. J Virol 1989;63:1181-7.
20. Stein B, Baldwin Jr AS, Ballard DW, Greene WC, Angel P, Herrlich P. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J 1993;12:3879-91.
21. Parham P, Brodsky FM. Partial purification and some properties of BB7.2: a cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28. Hum Immunol 1981;3:277-99.
22. McMichael AJ, Parham P, Rust N, Brodsky F. A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17. Hum Immunol 1980;1:121-9.
23. Stam J, Vroom TM, Peters PJ, Pastoors EB, Ploegh HL. HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryoimmuno-electron microscopy. Int Immunol 1989;2:113-25.
24. Barnstable CJ, Bodmer WF, Brown G, et al. Production of monoclonal antibodies to group A erythrocytes, HLA and other cell surface antigens - new tools for genetic analysis. Cell 1978;14:9-20.
25. Ways JP, Parham P. The antigenic structure of HLA-A2: an analysis with competitive binding assays and monoclonal antibodies. J Immunol 1983;131:856-63.
26. Warburton RJ, Matsui M, Rowland-Jones SL, et al. Mutation of the α2 domain disulfide bridge of the class I molecule HLA-A*0201: effect on maturation and peptide presentation. Hum Immunol 1994;39:261-71.
27. Cogswell PC, Scheinman RI, Baldwin Jr AS. Promoter of the human NF-κB p50/p105 gene: regulation by NF-κB subunits and by c-REL. J Immunol 1993;150:2794-804.
28. Matsui M, Hioe CE, Frelinger JA. Roles of the six peptide-binding pockets of the HLA-A2 molecule in allorecognition by human cytotoxic T-cell clones. Proc Natl Acad Sci USA 1993;90:674-8.
29. Caputo A, Sodroski JG, Haseltine WE. Constitutive expression of HIV-1 tat protein in human Jurkat T cells using a BK virus vector. J Acquir Immune Defic Syndr 1990;3:372-9.
30. Myers G, Korber B, Wain-Jobson S, Smith RF, Pavlakis GN, eds. Human retroviruses and AIDS, 1993. Los Alamos, NM: Alamos National Laboratory, 1993.
31. Purvis SF, Georges DL, Williams TM, Lederman MM. Suppression of interleukin-2 and interleukin-2 receptor expres- sion in Jurkat cells stably expressing the human immunodeficiency virus Tat protein. Cell Immunol 1992;144:32-42.
32. Subramanyam M, Gutheil WG, Bachovchin WW, Huber BT. Mechanism of HIV-1 Tat induced inhibition of antigen-specific T cell responsiveness. J Immunol 1993;150:2544-53.
33. Gutheil WG, Subramanyam M, Flentke GR, et al. Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity. Proc Natl Acad Sci USA 1994;91:6594-8.
34. Ensoli B, Barillari G, Salahuddin SG, Gallo RC, Wong-Staal F. Tat protein of HIV-1 stimulated growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 1990;345:84-6.
35. Frankel AD, Pabo CO. Cellular uptake of the Tat protein from human immunodeficiency virus. Cell 1988;55:1189-93.