Nicotine induces human neutrophils to produce IL-8 through the generation of peroxynitrite and subsequent activation of NF-κB

Journal of Leukocyte Biology

Volumn 74, Issue 5, 2003, Pages 942-951

  Iho, Sumiko ^a   Tanaka, Yukie ^a   Takauji, Rumiko ^e   Kobayashi, Chino ^a   Muramatsu, Ikunobu ^a   Iwasaki, Hiromichi ^a   Nakamura, Kishiko ^b   Sasaki, Yutaka ^c   Nakao, Kazuwa ^c   Takahashi, Takayuki ^d  

^a UNIVERSITY OF FUKUI   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

^e NONE

Author keywords

Chemokine; I B; Leukocytosis; Reactive oxygen intermediates; Tobacco smoker

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; N(G) NITRO DEXTRO ARGININE METHYL ESTER; NICOTINE; NICOTINIC RECEPTOR; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; SUPEROXIDE; SYNAPTOTAGMIN;

CHRONOSEQUENCE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LEUKOCYTE FUNCTION; NEUTROPHILIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION;

HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-8; KINETICS; NEUTROPHILS; NF-KAPPA B; NG-NITROARGININE METHYL ESTER; NICOTINE; NITRIC OXIDE; PEROXIDASE; PEROXYNITROUS ACID; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; SMOKING; TUMOR NECROSIS FACTOR-ALPHA;

NICOTIANA TABACUM;

EID: 9144220309     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1202626     Document Type: Conference Paper

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