Fluid-phase pinocytosis of LDL by macrophages: A novel target to reduce macrophage cholesterol accumulation in atherosclerotic lesions

Current Pharmaceutical Design

Volumn 19, Issue 33, 2013, Pages 5865-5872

  Kruth, Howard S ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Atherosclerosis; Cholesterol; Fluid phase pinocytosis; GM CSF; LDL; LXR; Macrophages; Macropinocytosis; MCSF; Phosphoinositide 3 kinase

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; 5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; CHOLESTEROL; COLONY STIMULATING FACTOR RECEPTOR; GW 2580; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; PROTEIN KINASE SYK; QUANTUM DOT; RUBOXISTAURIN; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROTIC PLAQUE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL TRANSFORMATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; DRUG TARGETING; FLUID PHASE PINOCYTOSIS; FOAM CELL; HUMAN; MACROPHAGE; MONOCYTE; NONHUMAN; PHENOTYPE; PINOCYTOSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CHOLESTEROL; FOAM CELLS; HUMANS; LIPOPROTEINS, LDL; MACROPHAGES; MOLECULAR TARGETED THERAPY; PINOCYTOSIS; PLAQUE, ATHEROSCLEROTIC;

EID: 84877135349     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319330005     Document Type: Article

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