Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kγ-dependent fluid-phase pinocytosis of native LDL

Journal of Lipid Research

Volumn 53, Issue 1, 2012, Pages 34-42

  Anzinger, Joshua J ^a   Chang, Janet ^a   Xu, Qing ^a   Barthwal, Manoj K ^a   Bohnacker, Thomas ^b   Wymann, Matthias P ^b   Kruth, Howard S ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Atherosclerosis; Cholesterol; Granulocytemacrophage colony stimulating factor; Low density lipoprotein; Phosphoinositide 3 kinase

Indexed keywords

5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; CD86 ANTIGEN; CHOLESTEROL; CYTOKINE; GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IODINE 125; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHOLESTEROL TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FOAM CELL; INCUBATION TIME; MACROPHAGE; MOUSE; NONHUMAN; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; CELL DIFFERENTIATION; CHOLESTEROL, LDL; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; FOAM CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; LIPOPROTEINS, LDL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; PINOCYTOSIS; QUINOXALINES; THIAZOLIDINEDIONES;

EID: 84455169833     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M018887     Document Type: Article

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