Increased expression of senescence markers in cystic fibrosis airways

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 6, 2013, Pages

  Fischer, Bernard M ^a   Wong, Jessica K ^a   Degan, Simone ^b,c   Kummarapurugu, Apparao B ^a   Zheng, Shuo ^a   Haridass, Prashamsha ^a   Voynow, Judith A ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

Neutrophil elastase; p16ink4a; Phospho Chk2; Phospho histone 2A.X; Telomere length

Indexed keywords

BIOLOGICAL MARKER; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE H2AX; LEUKOCYTE ELASTASE; CDK4 PROTEIN, HUMAN; H2AFX PROTEIN, HUMAN; HISTONE; PROTEIN SERINE THREONINE KINASE;

AIRWAY; ARTICLE; BRONCHUS MUCOSA; CELL AGING; CELL DAMAGE; CELL LYSATE; CONTROLLED STUDY; CYSTIC FIBROSIS; DNA DAMAGE; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; UPREGULATION; BRONCHUS; CASE CONTROL STUDY; CELL CULTURE; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA; TELOMERE;

BIOLOGICAL MARKERS; BRONCHI; CASE-CONTROL STUDIES; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYSTIC FIBROSIS; DNA DAMAGE; HISTONES; HUMANS; LEUKOCYTE ELASTASE; PROTEIN-SERINE-THREONINE KINASES; RESPIRATORY MUCOSA; TELOMERE; UP-REGULATION;

MLCS; MLOWN;

EID: 84877133556     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00091.2012     Document Type: Article

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