Vinorelbine-Induced Oxidative Injury in Human Endothelial Cells Mediated by AMPK/PKC/NADPH/NF-κB Pathways

Cell Biochemistry and Biophysics

Volumn 62, Issue 3, 2012, Pages 467-479

  Tsai, Kun Ling ^a   Chiu, Tsan Hung ^b   Tsai, Mei Hsueh ^c   Chen, Hsiao Yun ^d   Ou, Hsiu Chung ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c 3M Company   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

AMPK; Endothelial cells; Oxidative stress; Reactive oxygen species; Vinorelbine tartrate

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; AMP ACTIVATED PROTEIN KINASE KINASE; AMP-ACTIVATED PROTEIN KINASE KINASE; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NAVELBINE; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RIBONUCLEOTIDE; VINBLASTINE;

ARTICLE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; HUMAN; METABOLISM; OXIDATIVE STRESS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

AMINOIMIDAZOLE CARBOXAMIDE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELLS, CULTURED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NADPH OXIDASE; NF-KAPPA B; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION; VINBLASTINE;

VINCA;

EID: 84858704647     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-011-9333-y     Document Type: Article

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