메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

A Novel Function of Novobiocin: Disrupting the Interaction of HIF 1α and p300/CBP through Direct Binding to the HIF1α C-Terminal Activation Domain

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CYSTEINE; GELDANAMYCIN; HISTIDINE; HISTONE ACETYLTRANSFERASE PCAF; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NOVOBIOCIN;

EID: 84877097768     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062014     Document Type: Article
Times cited : (36)

References (38)
  • 2
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL, (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12: 5447-5454.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 3
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, et al. (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399: 271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3    Clifford, S.C.4    Vaux, E.C.5
  • 4
    • 0037108807 scopus 로고    scopus 로고
    • Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
    • Ivan M, Haberberger T, Gervasi DC, Michelson KS, Günzler V, et al. (2002) Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proc Natl Acad Sci 15: 13459-13464.
    • (2002) Proc Natl Acad Sci , vol.15 , pp. 13459-13464
    • Ivan, M.1    Haberberger, T.2    Gervasi, D.C.3    Michelson, K.S.4    Günzler, V.5
  • 5
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW, (1998) Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol 201: 1153-1162.
    • (1998) J Exp Biol , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 6
    • 80051600794 scopus 로고    scopus 로고
    • HIF1α effects on angiogenic potential in human small cell lung carcinoma
    • doi:10.1186/1756-9966-30-77
    • Wan J, Chai H, Yu Z, Ge W, Kang N, et al. (2011) HIF1α effects on angiogenic potential in human small cell lung carcinoma. J Exp Clin Cancer Res doi:10.1186/1756-9966-30-77.
    • (2011) J Exp Clin Cancer Res
    • Wan, J.1    Chai, H.2    Yu, Z.3    Ge, W.4    Kang, N.5
  • 7
    • 84855436875 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer
    • Schwab LP, Peacock DL, Majumdar D, Ingels JF, Jensen LC, et al. (2011) Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer. Breast Cancer Res 14: R6.
    • (2011) Breast Cancer Res , vol.14
    • Schwab, L.P.1    Peacock, D.L.2    Majumdar, D.3    Ingels, J.F.4    Jensen, L.C.5
  • 8
  • 9
    • 0034686027 scopus 로고    scopus 로고
    • The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules
    • Newton AL, Sharpe BK, Kwan A, Mackay JP, Crossley M, (2000) The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules. J Biol Chem 275: 15128-15134.
    • (2000) J Biol Chem , vol.275 , pp. 15128-15134
    • Newton, A.L.1    Sharpe, B.K.2    Kwan, A.3    Mackay, J.P.4    Crossley, M.5
  • 10
    • 3142622930 scopus 로고    scopus 로고
    • Small molecue blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
    • Kung AL, Zabludoff SD, France DC, Freedman SJ, Tanner EA, et al. (2004) Small molecue blockade of transcriptional coactivation of the hypoxia-inducible factor pathway. Cancer Cell 6: 33-43.
    • (2004) Cancer Cell , vol.6 , pp. 33-43
    • Kung, A.L.1    Zabludoff, S.D.2    France, D.C.3    Freedman, S.J.4    Tanner, E.A.5
  • 11
    • 78049434478 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible transcription factor complex with designed epipolythiodiketopiperazine
    • Kushal S, Wang H, László CF, Szábo LZ, Olenyuk BZ, (2011) Inhibition of hypoxia-inducible transcription factor complex with designed epipolythiodiketopiperazine. Biopolymers 95: 8-16.
    • (2011) Biopolymers , vol.95 , pp. 8-16
    • Kushal, S.1    Wang, H.2    László, C.F.3    Szábo, L.Z.4    Olenyuk, B.Z.5
  • 12
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • Kung AL, Wang S, Klco JM, Kaelin WG, Livingston DM, (2000) Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med 6: 1335-1340.
    • (2000) Nat Med , vol.6 , pp. 1335-1340
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin, W.G.4    Livingston, D.M.5
  • 13
    • 33745637200 scopus 로고    scopus 로고
    • Effects of geldanamycin on HIF-1 alpha mediated angiogenesis and invasion in prostate cancer cells
    • Alqawi O, Moghaddas M, Singh G, (2006) Effects of geldanamycin on HIF-1 alpha mediated angiogenesis and invasion in prostate cancer cells. Prostate Cancer Prostatic Dis 9: 126-135.
    • (2006) Prostate Cancer Prostatic Dis , vol.9 , pp. 126-135
    • Alqawi, O.1    Moghaddas, M.2    Singh, G.3
  • 14
    • 31544469773 scopus 로고    scopus 로고
    • Amphotericin B blunts erythropoietin response to hypoxia by reinforcing FIH-mediated repression of HIF-1
    • Yeo EJ, Ryu JH, Cho YS, Huang LE, Kim MS, et al. (2006) Amphotericin B blunts erythropoietin response to hypoxia by reinforcing FIH-mediated repression of HIF-1. Blood 107: 916-923.
    • (2006) Blood , vol.107 , pp. 916-923
    • Yeo, E.J.1    Ryu, J.H.2    Cho, Y.S.3    Huang, L.E.4    Kim, M.S.5
  • 15
    • 0034594644 scopus 로고    scopus 로고
    • Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins
    • Marcu MG, Schulte TW, Neckers L, (2000) Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins. J Natl Cancer Inst 92: 242-248.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 242-248
    • Marcu, M.G.1    Schulte, T.W.2    Neckers, L.3
  • 16
    • 0034594644 scopus 로고    scopus 로고
    • Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins
    • Marcu MG, Schulte TW, Neckers L, (2000) Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins. J Natl Cancer Inst 92: 242-248.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 242-248
    • Marcu, M.G.1    Schulte, T.W.2    Neckers, L.3
  • 17
    • 77951122152 scopus 로고    scopus 로고
    • Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells
    • Luo XG, Zou JN, Wang SZ, Zhang TC, Xi T, (2010) Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells. IUBMB Life 62: 194-199.
    • (2010) IUBMB Life , vol.62 , pp. 194-199
    • Luo, X.G.1    Zou, J.N.2    Wang, S.Z.3    Zhang, T.C.4    Xi, T.5
  • 18
    • 80255138632 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors
    • Kusuma BR, Duerfeldt AS, Blagg BS, (2011) Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors. Bioorg Med Chem Lett 21: 7170-7174.
    • (2011) Bioorg Med Chem Lett , vol.21 , pp. 7170-7174
    • Kusuma, B.R.1    Duerfeldt, A.S.2    Blagg, B.S.3
  • 19
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG, (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic. Acids. Res 11: 1475-1489.
    • (1983) Nucleic. Acids. Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 20
    • 0344823945 scopus 로고    scopus 로고
    • Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation
    • Akagi T, Sasai K, Hanafusa H, (2003) Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation. Proc Natl Acad Sci USA 100: 13567-13572.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13567-13572
    • Akagi, T.1    Sasai, K.2    Hanafusa, H.3
  • 22
  • 23
    • 0035971148 scopus 로고    scopus 로고
    • Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer
    • Hofr C, Brabec V, (2001) Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer. J Biol Chem 276: 9655-9661.
    • (2001) J Biol Chem , vol.276 , pp. 9655-9661
    • Hofr, C.1    Brabec, V.2
  • 24
    • 0023628351 scopus 로고
    • The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes
    • Eastman A, (1987) The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. Pharmacol Ther 34: 155-166.
    • (1987) Pharmacol Ther , vol.34 , pp. 155-166
    • Eastman, A.1
  • 25
    • 77955868586 scopus 로고    scopus 로고
    • Translesion DNA synthesis polymerases in DNA interstrand crosslink repair
    • Ho TV, Schärer OD, (2010) Translesion DNA synthesis polymerases in DNA interstrand crosslink repair. Environ Mol Mutagen 51: 552-566.
    • (2010) Environ Mol Mutagen , vol.51 , pp. 552-566
    • Ho, T.V.1    Schärer, O.D.2
  • 27
    • 70449517334 scopus 로고    scopus 로고
    • Expression of delta-like ligand 4 (DII4) and markers of hypoxia in colon cancer
    • Jubb AM, Turley H, Moeller HC, Steers G, Han C, et al. (2009) Expression of delta-like ligand 4 (DII4) and markers of hypoxia in colon cancer. Br, J. Cancer 101: 1749-1757.
    • (2009) Br, J. Cancer , vol.101 , pp. 1749-1757
    • Jubb, A.M.1    Turley, H.2    Moeller, H.C.3    Steers, G.4    Han, C.5
  • 28
    • 84860003307 scopus 로고    scopus 로고
    • Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR pathway by interaction of carbonic anhydrase IX (CA9) in tumorigenesis
    • Kim BR, Shin HJ, Kim JY, Byun HJ, Lee JH, et al. (2012) Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR pathway by interaction of carbonic anhydrase IX (CA9) in tumorigenesis. Cellular Signalling 24: 1406-1413.
    • (2012) Cellular Signalling , vol.24 , pp. 1406-1413
    • Kim, B.R.1    Shin, H.J.2    Kim, J.Y.3    Byun, H.J.4    Lee, J.H.5
  • 29
    • 77952878558 scopus 로고    scopus 로고
    • Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, daignosis, and therapy
    • Stillebroer AB, Mulders PF, Boerman OC, Oyen WJ, Oosterwijk E, (2010) Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, daignosis, and therapy. Eur Urol 58: 75-83.
    • (2010) Eur Urol , vol.58 , pp. 75-83
    • Stillebroer, A.B.1    Mulders, P.F.2    Boerman, O.C.3    Oyen, W.J.4    Oosterwijk, E.5
  • 30
    • 68049105076 scopus 로고    scopus 로고
    • Role of hypoxia in the hallmarks of human cancer
    • Ruan K, Song G, Ouyang G, (2009) Role of hypoxia in the hallmarks of human cancer. J Cell Biochem 107: 1053-1062.
    • (2009) J Cell Biochem , vol.107 , pp. 1053-1062
    • Ruan, K.1    Song, G.2    Ouyang, G.3
  • 31
    • 33846211525 scopus 로고    scopus 로고
    • Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
    • Hussain SA, Ganesan R, Reynolds G, Gross L, Stevens A, et al. (2007) Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer. Br J Cancer 96: 104-109.
    • (2007) Br J Cancer , vol.96 , pp. 104-109
    • Hussain, S.A.1    Ganesan, R.2    Reynolds, G.3    Gross, L.4    Stevens, A.5
  • 32
    • 63449135054 scopus 로고    scopus 로고
    • Carbonic anhydrase IX in bladder cancer: a diagnostic, prognostic, and therapeutic molecular marker
    • Klatte T, Seligson DB, Rao JY, Yu H, de Martino M, et al. (2009) Carbonic anhydrase IX in bladder cancer: a diagnostic, prognostic, and therapeutic molecular marker. Cancer 115: 1448-1458.
    • (2009) Cancer , vol.115 , pp. 1448-1458
    • Klatte, T.1    Seligson, D.B.2    Rao, J.Y.3    Yu, H.4    de Martino, M.5
  • 33
    • 0037315252 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer
    • Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, et al. (2003) Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J Clin Oncol 21: 473-482.
    • (2003) J Clin Oncol , vol.21 , pp. 473-482
    • Swinson, D.E.1    Jones, J.L.2    Richardson, D.3    Wykoff, C.4    Turley, H.5
  • 34
    • 36048987954 scopus 로고    scopus 로고
    • Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma
    • Leibovich BC, Sheinin Y, Lohse CM, Thompson RH, Cheville JC, et al. (2007) Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma. J Clin Oncol 25: 4757-4764.
    • (2007) J Clin Oncol , vol.25 , pp. 4757-4764
    • Leibovich, B.C.1    Sheinin, Y.2    Lohse, C.M.3    Thompson, R.H.4    Cheville, J.C.5
  • 35
    • 78649636616 scopus 로고    scopus 로고
    • Carbonic anhydrase 9 in clear cell renal cell carcnoma: a marker for diagnosis, prognosis and treatment
    • Tostain J, Li G, Gentil-Perret A, Gigante M, (2010) Carbonic anhydrase 9 in clear cell renal cell carcnoma: a marker for diagnosis, prognosis and treatment. Eur J Cancer 46: 3141-3148.
    • (2010) Eur J Cancer , vol.46 , pp. 3141-3148
    • Tostain, J.1    Li, G.2    Gentil-Perret, A.3    Gigante, M.4
  • 36
    • 0030835515 scopus 로고    scopus 로고
    • Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney
    • Liao SY, Aurelio ON, Jan K, Zavada J, Stanbridge EJ, (1997) Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney. Cancer Res 57: 2827-2831.
    • (1997) Cancer Res , vol.57 , pp. 2827-2831
    • Liao, S.Y.1    Aurelio, O.N.2    Jan, K.3    Zavada, J.4    Stanbridge, E.J.5
  • 37
    • 74249108175 scopus 로고    scopus 로고
    • Alternative strategies of Hsp90 modulation for treatment of cancer and other diseases
    • Brandt GE, Blagg BS, (2009) Alternative strategies of Hsp90 modulation for treatment of cancer and other diseases. Curr Med Chem 9: 1447-1461.
    • (2009) Curr Med Chem , vol.9 , pp. 1447-1461
    • Brandt, G.E.1    Blagg, B.S.2
  • 38
    • 0034711270 scopus 로고    scopus 로고
    • The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone
    • Marcu MG, Chadli A, Bouhouche I, Catelli M, Neckers LM, (2000) The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone. J Biol Chem 275: 37181-37186.
    • (2000) J Biol Chem , vol.275 , pp. 37181-37186
    • Marcu, M.G.1    Chadli, A.2    Bouhouche, I.3    Catelli, M.4    Neckers, L.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.