Vitamin D status and outcomes after renal transplantation

Journal of the American Society of Nephrology

Volumn 24, Issue 5, 2013, Pages 831-841

  Bienaimé, Frank ^a,b   Girard, Delphine ^b   Anglicheau, Dany ^a,b   Canaud, Guillaume ^a,b   Souberbielle, Jean Claude ^a,b   Kreis, Henri ^b   Noël, Laure Hélène ^a,b   Friedlander, Gérard ^a,b,c   Elie, Caroline ^b   Legendre, Christophe ^a,b   Prié, Dominique ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM; FIBROBLAST GROWTH FACTOR 23; PARATHYROID HORMONE; PHOSPHORUS;

ADULT; ARTICLE; ATROPHY; CALCIUM BLOOD LEVEL; COHORT ANALYSIS; DISEASE COURSE; FEMALE; GLOMERULUS FILTRATION RATE; GRAFT FAILURE; GRAFT RECIPIENT; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; KIDNEY FIBROSIS; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SCORING SYSTEM; VITAMIN BLOOD LEVEL;

EID: 84877091370     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012060614     Document Type: Article

References (66)

1. Wolfe RA, Ashby VB,Milford EL, Ojo AO, Ettenger RE, Agodoa LY,Held PJ, Port FK: Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 341: 1725-1730, 1999
2. Hariharan S, McBride MA, Cherikh WS, Tolleris CB, Bresnahan BA, Johnson CP: Post-transplant renal function in the first year predicts long-term kidney transplant survival. Kidney Int 62: 311-318, 2002 (Pubitemid 34754077)
3. Kasiske BL, Andany MA, Danielson B: A thirty percent chronic decline in inverse serum creatinine is an excellent predictor of late renal allograft failure. Am J Kidney Dis 39: 762-768, 2002 (Pubitemid 34263350)
4. Cheng JB, Levine MA, Bell NH, Mangelsdorf DJ, Russell DW: Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc Natl Acad Sci U S A 101: 7711-7715, 2004 (Pubitemid 38658094)
5. Vanhooke JL, Prahl JM, Kimmel-Jehan C, Mendelsohn M, Danielson EW, Healy KD, DeLuca HF: CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1alpha-hydroxylase promoter activity in the skin. Proc Natl Acad Sci U S A 103: 75-80, 2006 (Pubitemid 43076107)
6. Shimada T, Kakitani M, Yamazaki Y, Hasegawa H, Takeuchi Y, Fujita T, Fukumoto S, Tomizuka K, Yamashita T: Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest 113: 561-568, 2004 (Pubitemid 38542505)
7. Kuhlmann A, Haas CS, Gross ML, Reulbach U, Holzinger M, Schwarz U, Ritz E, Amann K: 1,25-Dihydroxyvitamin D3 decreases podocyte loss and podocyte hypertrophy in the subtotally nephrectomized rat. Am J Physiol Renal Physiol 286: F526-F533, 2004 (Pubitemid 38233647)
8. Migliori M, Giovannini L, Panichi V, Filippi C, Taccola D, Origlia N, Mannari C, Camussi G: Treatment with 1,25-dihydroxyvitamin D3 preserves glomerular slit diaphragm-associated protein expression in experimental glomerulonephritis. Int J Immunopathol Pharmacol 18: 779-790, 2005
9. Xiao H, Shi W, Liu S, Wang W, Zhang B, Zhang Y, Xu L, Liang X, Liang Y: 1,25-Dihydroxyvitamin D(3) prevents puromycin aminonucleosideinduced apoptosis of glomerular podocytes by activating the phosphatidylinositol 3-kinase/Akt-signaling pathway. Am J Nephrol 30: 34-43, 2009
10. Zou MS, Yu J, Zhou JH, Nie GM, Ding DS, Luo LM, Xu HT, He WS: 1,25-Dihydroxyvitamin D3 ameliorates podocytopenia in rats with adriamycin-induced nephropathy. Intern Med 49: 2677-2686, 2010
11. Zou MS, Yu J, Nie GM, He WS, Luo LM, Xu HT: 1, 25-dihydroxyvitamin D3 decreases adriamycin-induced podocyte apoptosis and loss. Int J Med Sci 7: 290-299, 2010
12. Wang XX, Jiang T, Shen Y, Santamaria H, Solis N, Arbeeny C, Levi M: Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism. Am J Physiol Renal Physiol 300: F801-F810, 2011
13. Zhang Y, Kong J, Deb DK, Chang A, Li YC: Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system. J Am Soc Nephrol 21: 966-973, 2010
14. He W, Kang YS, Dai C, Liu Y: Blockade of Wnt/β-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury. J Am Soc Nephrol 22: 90-103, 2011
15. García IM, Altamirano L, Mazzei LJ, Fornés MW, Molina MN, Ferder L, Manucha W: Role of mitochondria in paricalcitol-mediated cytoprotection during obstructive nephropathy. Am J Physiol Renal Physiol 302: F1595-F1605, 2012
16. Liu LJ, Lv JC, Shi SF, Chen YQ, Zhang H, Wang HY: Oral calcitriol for reduction of proteinuria in patients with IgA nephropathy: A randomized controlled trial. Am J Kidney Dis 59: 67-74, 2012
17. de Zeeuw D, Agarwal R, Amdahl M, Audhya P, Coyne D, Garimella T, Parving HH, Pritchett Y, Remuzzi G, Ritz E, Andress D: Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): A randomised controlled trial. Lancet 376: 1543-1551, 2010
18. Melamed ML, Astor B, Michos ED, Hostetter TH, Powe NR, Muntner P: 25-hydroxyvitamin D levels, race, and the progression of kidney disease. J Am Soc Nephrol 20: 2631-2639, 2009
19. de Boer IH, Katz R,Chonchol M, Ix JH, Sarnak MJ, Shlipak MG, Siscovick DS, Kestenbaum B: Serum 25-hydroxyvitamin D and change in estimated glomerular filtration rate. Clin J Am Soc Nephrol 6: 2141-2149, 2011
20. Serón D, Moreso F: Protocol biopsies in renal transplantation: Prognostic value of structural monitoring. Kidney Int 72: 690-697, 2007 (Pubitemid 47373786)
21. Dirks-Naylor AJ, Lennon-Edwards S: The effects of vitamin D on skeletal muscle function and cellular signaling. J Steroid Biochem Mol Biol 125: 159-168, 2011
22. Endo I, Inoue D, Mitsui T, Umaki Y, Akaike M, Yoshizawa T, Kato S, Matsumoto T: Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors. Endocrinology 144: 5138-5144, 2003 (Pubitemid 37476038)
23. Oh JH, Kim SH, Kim JH, Shin YH, Yoon JP, Oh CH: The level of vitamin D in the serum correlates with fatty degeneration of the muscles of the rotator cuff. J Bone Joint Surg Br 91: 1587-1593, 2009
24. Tagliafico AS, Ameri P, Bovio M, Puntoni M, Capaccio E, Murialdo G, Martinoli C: Relationship between fatty degeneration of thigh muscles and vitamin D status in the elderly: A preliminary MRI study. AJR Am J Roentgenol 194: 728-734, 2010
25. Agarwal R, Hynson JE, Hecht TJ, Light RP, Sinha AD: Short-term vitamin D receptor activation increases serum creatinine due to increased production with no effect on the glomerular filtration rate. Kidney Int 80: 1073-1079, 2011
26. Hewison M: Vitamin D and innate and adaptive immunity. Vitam Horm 86: 23-62, 2011
27. Ahmadpoor P, Ilkhanizadeh B, Ghasemmahdi L, Makhdoomi K, Ghafari A: Effect of active vitamin D on expression of co-stimulatory molecules and HLA-DR in renal transplant recipients. Exp Clin Transplant 7: 99-103, 2009
28. Sawinski D, Uribarri J, Peace D, Yao T,Wauhop P, Trzcinka P, Ostrow K, Poggio ED, Heeger PS: 25-OH-vitamin D deficiency and cellular alloimmunity as measured by panel of reactive T cell testing in dialysis patients. Am J Transplant 10: 2287-2295, 2010
29. Hullett DA, Laeseke PF, Malin G, Nessel R, Sollinger HW, Becker BN: Prevention of chronic allograft nephropathy with vitamin D. Transpl Int 18: 1175-1186, 2005 (Pubitemid 41726762)
30. Schwarz U, Amann K, Orth SR, Simonaviciene A, Wessels S, Ritz E: Effect of 1,25 (OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats. Kidney Int 53: 1696-1705, 1998 (Pubitemid 28243754)
31. Hirata M, Makibayashi K, Katsumata K, Kusano K, Watanabe T, Fukushima N, Doi T: 22-Oxacalcitriol prevents progressive glomerulosclerosis without adversely affecting calcium and phosphorus metabolism in subtotally nephrectomized rats. Nephrol Dial Transplant 17: 2132-2137, 2002 (Pubitemid 35446668)
32. Mizobuchi M, Morrissey J, Finch JL, Martin DR, Liapis H, Akizawa T, Slatopolsky E: Combination therapy with an angiotensin-converting enzyme inhibitor and a vitamin Danalog suppresses the progression of renal insufficiency in uremic rats. J Am Soc Nephrol 18: 1796-1806, 2007 (Pubitemid 46870316)
33. Panichi V, Migliori M, Taccola D, Filippi C, De Nisco L, Giovannini L, Palla R, Tetta C, Camussi G: Effects of 1,25(OH)2D3 in experimental mesangial proliferative nephritis in rats. Kidney Int 60: 87-95, 2001 (Pubitemid 32587543)
34. Li YC: Podocytes as target of vitamin D. Curr Diabetes Rev 7: 35-40, 2011
35. Li YC, Kong J,Wei M, Chen ZF, Liu SQ, Cao LP: 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest 110: 229-238, 2002 (Pubitemid 34787360)
36. Dusso A, Arcidiacono MV, Yang J, Tokumoto M: Vitamin D inhibition of TACE and prevention of renal osteodystrophy and cardiovascular mortality. J Steroid Biochem Mol Biol 121: 193-198, 2010
37. Finch JL, Suarez EB, Husain K, Ferder L, Cardema MC, Glenn DJ, Gardner DG, Liapis H, Slatopolsky E: Effect of combining an ACE inhibitor and a VDR activator on glomerulosclerosis, proteinuria, and renal oxidative stress in uremic rats. Am J Physiol Renal Physiol 302: F141-F149, 2012
38. Fishbane S, Chittineni H, Packman M, Dutka P, Ali N, Durie N: Oral paricalcitol in the treatment of patients with CKD and proteinuria: A randomized trial. Am J Kidney Dis 54: 647-652, 2009
39. Forman JP, Giovannucci E, Holmes MD, Bischoff-Ferrari HA, Tworoger SS, Willett WC, Curhan GC: Plasma 25-hydroxyvitamin D levels and risk of incident hypertension. Hypertension 49: 1063-1069, 2007 (Pubitemid 351664326)
40. Melamed ML, Michos ED, Post W, Astor B: 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 168: 1629-1637, 2008
41. Jenab M, Bueno-de-Mesquita HB, Ferrari P, van Duijnhoven FJ, Norat T, Pischon T, Jansen EH, Slimani N, Byrnes G, Rinaldi S, Tjønneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Morois S, Kaaks R, Linseisen J, Boeing H, Bergmann MM, Trichopoulou A, Misirli G, Trichopoulos D, Berrino F, Vineis P, Panico S, Palli D, Tumino R, Ros MM, van Gils CH, Peeters PH, Brustad M, Lund E, Tormo MJ, Ardanaz E, Rodríguez L, Sánchez MJ, Dorronsoro M, Gonzalez CA, Hallmans G, Palmqvist R, Roddam A, Key TJ, Khaw KT, Autier P, Hainaut P, Riboli E: Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations: A nested case-control study. BMJ 340: b5500, 2010
42. Eisman JA, DeLuca HF: Intestinal 1,25-dihydroxyvitamin D3 binding protein: specificity of binding. Steroids 30: 245-257, 1977 (Pubitemid 8216008)
43. Bienaimé F, Prié D, Friedlander G, Souberbielle JC: Vitamin D metabolism and activity in the parathyroid gland. Mol Cell Endocrinol 347: 30-41, 2011
44. Demay MB, Kiernan MS, DeLuca HF, Kronenberg HM: Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A 89: 8097-8101, 1992
45. Meir T, Levi R, Lieben L, Libutti S, Carmeliet G, Bouillon R, Silver J, Naveh-Many T: Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology. Am J Physiol Renal Physiol 297: F1192-F1198, 2009
46. Vieth R, Ladak Y,Walfish PG:Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D. J Clin Endocrinol Metab 88: 185-191, 2003 (Pubitemid 36115163)
47. Guillemant J, Cabrol S, Allemandou A, Peres G, Guillemant S: Vitamin D-dependent seasonal variation of PTH in growing male adolescents. Bone 17: 513-516, 1995 (Pubitemid 26017570)
48. Christensen MH, Lien EA, Hustad S, Almås B: Seasonal and age-related differences in serum 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone in patients from Western Norway. Scand J Clin Lab Invest 70: 281-286, 2010
49. Tomida K, Hamano T, Mikami S, Fujii N, Okada N, Matsui I, Nagasawa Y, Moriyama T, Ito T, Imai E, Isaka Y, Rakugi H: Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in non-diabetic predialysis CKD patients. Bone 44: 678-683, 2009
50. Zhang ZL, Ding XF, Tong J, Li BY: Partial rescue of the phenotype in 1α-hydroxylase gene knockout mice by vitamin D3 injection. Endocr Res 36: 101-108, 2011
51. Ritter CS, Armbrecht HJ, Slatopolsky E, Brown AJ: 25-Hydroxyvitamin D(3) suppresses PTH synthesis and secretion by bovine parathyroid cells. Kidney Int 70: 654-659, 2006 (Pubitemid 44215339)
52. Segersten U, Correa P, Hewison M, Hellman P, Dralle H, Carling T, Akerström G, Westin G: 25-hydroxyvitamin D(3)-1alpha-hydroxylase expression in normal and pathological parathyroid glands. J Clin Endocrinol Metab 87: 2967-2972, 2002 (Pubitemid 34655371)
53. Kawahara M, Iwasaki Y, Sakaguchi K, Taguchi T, Nishiyama M, Nigawara T, Tsugita M, Kambayashi M, Suda T, Hashimoto K: Predominant role of 25OHD in the negative regulation of PTH expression: clinical relevance for hypovitaminosis D. Life Sci 82: 677-683, 2008
54. Cross HS: Extrarenal vitamin D hydroxylase expression and activity in normal and malignant cells: Modification of expression by epigenetic mechanisms and dietary substances. Nutr Rev 65: S108-S112, 2007
55. Wang Y, Zhou J, Minto AW, Hack BK, Alexander JJ, Haas M, Li YC, Heilig CW, Quigg RJ: Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathy. Kidney Int 70: 882-891, 2006
56. Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL: Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311: 1770-1773, 2006
57. Schwartz GG, Eads D, Rao A, Cramer SD, Willingham MC, Chen TC, Jamieson DP, Wang L, Burnstein KL, Holick MF, Koumenis C: Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3. Carcinogenesis 25: 1015-1026, 2004 (Pubitemid 38898637)
58. Matias PJ, Jorge C, Ferreira C, Borges M, Aires I, Amaral T, Gil C, Cortez J, Ferreira A: Cholecalciferol supplementation in hemodialysis patients: Effects on mineral metabolism, inflammation, and cardiac dimension parameters. Clin J Am Soc Nephrol 5: 905-911, 2010
59. Thadhani R, Appelbaum E, Pritchett Y, Chang Y, Wenger J, Tamez H, Bhan I, Agarwal R, Zoccali C, Wanner C, Lloyd-Jones D, Cannata J, Thompson BT, Andress D, Zhang W, Packham D, Singh B, Zehnder D, Shah A, Pachika A, Manning WJ, Solomon SD: Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: The PRIMO randomized controlled trial. JAMA 307: 674-684, 2012
60. Chen S, Glenn DJ, Ni W, Grigsby CL, Olsen K, Nishimoto M, Law CS, Gardner DG: Expression of the vitamin D receptor is increased in the hypertrophic heart. Hypertension 52: 1106-1112, 2008
61. Courbebaisse M, Thervet E, Souberbielle JC, Zuber J, Eladari D, Martinez F, Mamzer-Bruneel MF, Urena P, Legendre C, Friedlander G, Prié D: Effects of vitamin D supplementation on the calcium-phosphate balance in renal transplant patients. Kidney Int 75: 646-651, 2009
62. Wissing KM, Broeders N, Moreno-Reyes R, Gervy C, Stallenberg B, Abramowicz D: A controlled study of vitamin D3 to prevent bone loss in renal-transplant patients receiving low doses of steroids. Transplantation 79: 108-115, 2005 (Pubitemid 40140008)
63. Kanter Berga J, Crespo Albiach J, Beltran Catalan S, Gavela Martinez E, Sancho Calabuig A, Avila Bernabeu A, Pallardo Mateu LM: Vitamin D deficiency in a renal transplant population: Safe repletion with moderate doses of calcidiol. Transplant Proc 42: 2917-2920, 2010
64. Foucher Y, Daguin P, Akl A, Kessler M, Ladrière M, Legendre C, Kreis H, Rostaing L, Kamar N, Mourad G, Garrigue V, Bayle F, H de Ligny B, Büchler M, Meier C, Daurès JP, Soulillou JP, Giral M: A clinical scoring system highly predictive of long-term kidney graft survival. Kidney Int 78: 1288-1294, 2010
65. Courbebaisse M, Diet C, Timsit MO, Mamzer MF, Thervet E, Noel LH, Legendre C, Friedlander G, Martinez F, Prié D: Effects of cinacalcet in renal transplant patients with hyperparathyroidism. Am J Nephrol 35: 341-348, 2012
66. Solez K, Colvin RB, Racusen LC, Sis B, Halloran PF, Birk PE, Campbell PM, Cascalho M, Collins AB, Demetris AJ, Drachenberg CB, Gibson IW, Grimm PC, Haas M, Lerut E, Liapis H, Mannon RB, Marcus PB, Mengel M, Mihatsch MJ, Nankivell BJ, Nickeleit V, Papadimitriou JC, Platt JL, Randhawa P, Roberts I, Salinas-Madriga L, Salomon DR, Seron D, Sheaff M, Weening JJ: Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'). Am J Transplant 7: 518-526, 2007 (Pubitemid 46376465)