A controlled study of vitamin D3 to prevent bone loss in renal-transplant patients receiving low doses of steroids

Transplantation

Volumn 79, Issue 1, 2005, Pages 108-115

  Wissing, K Martin ^a   Broeders, Nilufer ^a   Moreno Reyes, Rodrigo ^a   Gervy, Christine ^a   Stallenberg, Bernard ^a   Abramowicz, Daniel ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

Bone density; Kidney transplantation; Osteoporosis; Parathyroid hormone; Vitamin D

Indexed keywords

BASILIXIMAB; CALCIUM; COLECALCIFEROL; CORTICOSTEROID; METHYLPREDNISOLONE; PARATHYROID HORMONE; PREDNISOLONE; THYMOCYTE ANTIBODY;

ACUTE GRAFT REJECTION; ADULT; ARTICLE; BONE DENSITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; FEMUR SHAFT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; LOW DRUG DOSE; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; OSTEOLYSIS; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; RECIPIENT; VITAMIN SUPPLEMENTATION;

ADULT; AGED; BONE DENSITY; CALCIUM; CHOLECALCIFEROL; FEMALE; GRAFT REJECTION; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; OSTEOPOROSIS; PARATHYROID HORMONE; PREDNISOLONE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 12344258729     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000149322.70295.A5     Document Type: Article

References (35)

1. Julian BA, Laskow DA, Dubovsky J, et al. Rapid loss of vertebral mineral density after renal transplantation. N Engl J Med 1991; 325: 544.
2. Grotz W, Nagel C, Poeschel D, et al. Effect of ibandronate on bone loss and renal function after kidney transplantation. J Am Soc Nephrol 2001; 12: 1530.
3. Fan SL, Almond MK, Ball E, et al. Pamidronate therapy as prevention of bone loss following renal transplantation 1. Kidney Int 2000; 57: 684.
4. Talalaj M, Gradowska L, Marcinowska-Suchowierska E, et al. Efficiency of preventive treatment of glucocorticoid-induced osteoporosis with 25-hydroxyvitamin D3 and calcium in kidney transplant patients. Transplant Proc 1996; 28: 3485.
5. Casez JP, Lippuner K, Horber FF, et al. Changes in bone mineral density over 18 months following kidney transplantation: the respective roles of prednisone and parathyroid hormone. Nephrol Dial Transplant 2002; 17: 1318.
6. Ramsey-Goldman R, Dunn JE, Dunlop DD, et al. Increased risk of fracture in patients receiving solid organ transplants. J Bone Miner Res 1999; 14: 456.
7. O'Shaughnessy EA, Dahl DC, Smith CL, et al. Risk factors for fractures in kidney transplantation. Transplantation 2002; 74: 362.
8. Aroldi A, Tarantino A, Montagnino G, et al. Effects of three immunosuppressive regimens on vertebral bone density in renal transplant recipients: a prospective study. Transplantation 1997; 63: 380.
9. Mikuls TR, Julian BA, Bartolucci A, et al. Bone mineral density changes within six months of renal transplantation. Transplantation 2003; 75: 49.
10. Ugur A, Guvener N, Isiklar I, et al. Osteoporosis after renal transplantation: single center experience. Transplantation 2001; 71: 645.
11. Grotz WH, Mundinger FA, Rasenack, J et al. Bone loss after kidney transplantation: a longitudinal study in 115 graft recipients. Nephrol Dial Transplant 1995; 10: 2096.
12. Westeel FP, Mazouz H, Ezaitouni F, et al. Cyclosporine bone remodeling effect prevents steroid osteopenia after kidney transplantation. Kidney Int 2000; 58: 1788.
13. Wolpaw T, Deal CL, Fleming-Brooks S, et al. Factors influencing vertebral bone density after renal transplantation. Transplantation 1994; 58: 1186.
14. Weinstein RS, Jilka RL, Parfitt AM, et al. Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J Clin Invest 1998; 102: 274.
15. Lukert BP, Raisz LG. Glucocorticoid-induced osteoporosis: pathogenesis and management. Ann Intern Med 1990; 112: 352.
16. Cohen A, Shane E. Osteoporosis after solid organ and bone marrow transplantation. Osteoporos Int 2003; 14: 617.
17. Recommendations for the prevention and treatment of glucocorticoid- induced osteoporosis: 2001 update. American College of Rheumatology Ad Hoc Committee on Glucocorticoid-induced Osteoporosis. Arthritis Rheum 2001; 44: 1496.
18. Chapuy MC, Arlot ME, Duboeuf F, et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med 1992; 327: 1637.
19. Dawson-Hughes B, Harris SS, Krall EA, et al. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 1997; 337: 670.
20. Buckley LM, Leib ES, Cartularo KS, et al. Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1996; 125: 961.
21. Amin S, LaValley MP, Simms RW, et al. The role of vitamin D in corticosteroid-induced osteoporosis: a meta-analytic approach. Arthritis Rheum 1999; 42: 1740.
22. Sheikh MS, Maguire JA, Emmett M, et al. Reduction of dietary phosphorus absorption by phosphorus binders. A theoretical, in vitro, and in vivo study. J Clin Invest 1989; 83: 66.
23. de Sevaux RG, Hoitsma AJ, van Hoof HJ, et al. Abnormal vitamin D metabolism and loss of bone mass after renal transplantation. Nephron Clin Pract 2003; 93: C21.
24. de Sevaux RG, Hoitsma AJ, Corstens FH, et al. Treatment with vitamin D and calcium reduces bone loss after renal transplantation: a randomized study. J Am Soc Nephrol 2002; 13: 1608.
25. Saag KG, Emkey R, Schnitzer TJ, et al. Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group. N Engl J Med 1998; 339: 292.
26. Reid DM, Hughes RA, Laan RF, et al. Efficacy and safety of daily risedronate in the treatment of corticosteroid-induced osteoporosis in men and women: a randomized trial. European Corticosteroid-Induced Osteoporosis Treatment Study. J Bone Miner Res 2000; 15: 1006.
27. Thomas MK, Lloyd-Jones DM, Thadhani RI, et al. Hypovitaminosis D in medical inpatients. N Engl J Med 1998; 338: 777.
28. Cannata-Andia JB, Gomez AC. Vitamin D deficiency: a neglected aspect of disturbed calcium metabolism in renal failure. Nephrol Dial Transplant 2002; 17: 1875.
29. Vieth R, Ladak Y, Walfish PG. Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D. J Clin Endocrinol Metab 2003; 88: 185.
30. Ghazali A, Fardellone P, Pruna A, et al. Is low plasma 25-(OH)vitamin D a major risk factor for hyperparathyroidism and Looser's zones independent of calcitriol? Kidney Int 1999; 55: 2169.
31. Fournier A, Fardellone P, Achard JM, et al. Importance of vitamin D repletion in uraemia. Nephrol Dial Transplant 1999; 14: 819.
32. Coco M, Glicklich D, Faugere MC, et al. Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate. J Am Soc Nephrol 2003; 14: 2669.
33. Monier-Faugere MC, Mawad H, Qi Q, et al. High prevalence of low bone turnover and occurrence of osteomalacia after kidney transplantation. J Am Soc Nephrol 2000; 11: 1093.
34. Fleisch H. Bisphosphonates in osteoporosis: an introduction. Osteoporos Int 1993; 3(Suppl 3): S3.
35. Sambrook P, Birmingham J, Kelly P, et al. Prevention of corticosteroid osteoporosis. A comparison of calcium, calcitriol, and calcitonin. N Engl J Med 1993; 328: 1747.