메뉴 건너뛰기




Volumn 434, Issue 2, 2013, Pages 363-369

Silencing of the P2X7 receptor enhances amyloid-β phagocytosis by microglia

Author keywords

Alzheimer's disease; Amyloid peptides; Microglia; P2X7 receptor; RNA interference

Indexed keywords

AMYLOID BETA PROTEIN; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; PURINERGIC P2X7 RECEPTOR;

EID: 84877061566     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.079     Document Type: Article
Times cited : (55)

References (29)
  • 1
    • 0034130707 scopus 로고    scopus 로고
    • Cell mediators of inflammation in the Alzheimer disease brain
    • Akiyama H., Arai T., Kondo H., et al. Cell mediators of inflammation in the Alzheimer disease brain. Alzheimer Dis. Assoc. Disord. 2000, 14:S47-S53.
    • (2000) Alzheimer Dis. Assoc. Disord. , vol.14
    • Akiyama, H.1    Arai, T.2    Kondo, H.3
  • 2
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • Streit W.J. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 2002, 40:133-139.
    • (2002) Glia , vol.40 , pp. 133-139
    • Streit, W.J.1
  • 3
    • 64249169414 scopus 로고    scopus 로고
    • Activation of microglia by amyloid-β requires P2X7 receptor expression
    • Sanz J.M., Chiozzi P., Ferrari D., et al. Activation of microglia by amyloid-β requires P2X7 receptor expression. J. Immunol. 2009, 182:4378-4385.
    • (2009) J. Immunol. , vol.182 , pp. 4378-4385
    • Sanz, J.M.1    Chiozzi, P.2    Ferrari, D.3
  • 4
    • 33846446438 scopus 로고    scopus 로고
    • Microglial transplantation increases amyloid-β clearance in Alzheimer model rats
    • Takata K., Kitamura Y., Yanagisawa D., et al. Microglial transplantation increases amyloid-β clearance in Alzheimer model rats. FEBS Lett. 2007, 581:475-478.
    • (2007) FEBS Lett. , vol.581 , pp. 475-478
    • Takata, K.1    Kitamura, Y.2    Yanagisawa, D.3
  • 5
    • 0036849021 scopus 로고    scopus 로고
    • Microglia and inflammatory mechanisms in the clearance of amyloid-β peptide
    • Rogers J., Strohmeyer R., Kovelowski C.J., et al. Microglia and inflammatory mechanisms in the clearance of amyloid-β peptide. Glia 2002, 40:260-269.
    • (2002) Glia , vol.40 , pp. 260-269
    • Rogers, J.1    Strohmeyer, R.2    Kovelowski, C.J.3
  • 7
    • 0028953529 scopus 로고
    • Activation of microglial cells by amyloid-β protein and interferon-β
    • Meda L., Cassatella M.A., Szendrei G.I., et al. Activation of microglial cells by amyloid-β protein and interferon-β. Nature 1995, 374:647-650.
    • (1995) Nature , vol.374 , pp. 647-650
    • Meda, L.1    Cassatella, M.A.2    Szendrei, G.I.3
  • 8
    • 33847613885 scopus 로고    scopus 로고
    • Inflammatory processes in Alzheimer's disease
    • Heneka M.T., O'Banion M.K. Inflammatory processes in Alzheimer's disease. J. Neuroimmunol. 2007, 184:69-91.
    • (2007) J. Neuroimmunol. , vol.184 , pp. 69-91
    • Heneka, M.T.1    O'Banion, M.K.2
  • 9
    • 84856668816 scopus 로고    scopus 로고
    • VIP enhances phagocytosis of fibrillar amyloid-β by microglia and attenuates amyloid deposition in the brain of APP/PS1 mice
    • Song M., Xiong J.X., Wang Y.Y., et al. VIP enhances phagocytosis of fibrillar amyloid-β by microglia and attenuates amyloid deposition in the brain of APP/PS1 mice. PLoS One 2012, 7:e29790.
    • (2012) PLoS One , vol.7
    • Song, M.1    Xiong, J.X.2    Wang, Y.Y.3
  • 10
    • 0242268945 scopus 로고    scopus 로고
    • Immunotherapeutic approaches to Alzheimer' s disease
    • Monsonego A., Weiner H.L. Immunotherapeutic approaches to Alzheimer' s disease. Science 2003, 302:834-838.
    • (2003) Science , vol.302 , pp. 834-838
    • Monsonego, A.1    Weiner, H.L.2
  • 11
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • North R.A. Molecular physiology of P2X receptors. Physiol. Rev. 2002, 82:1013-1067.
    • (2002) Physiol. Rev. , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 12
    • 64849087753 scopus 로고    scopus 로고
    • The P2X7 receptor drives microglial activation and proliferation: a trophic role for the P2X7R pore
    • Monif M., Reid C.A., Powell K.L., et al. The P2X7 receptor drives microglial activation and proliferation: a trophic role for the P2X7R pore. J. Neurosci. 2009, 29:3781-3791.
    • (2009) J. Neurosci. , vol.29 , pp. 3781-3791
    • Monif, M.1    Reid, C.A.2    Powell, K.L.3
  • 13
    • 0038143359 scopus 로고    scopus 로고
    • P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
    • Parvathenani L.K., Tertyshnikova S., Greco C.R., et al. P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J. Biol. Chem. 2003, 278:13309-13317.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13309-13317
    • Parvathenani, L.K.1    Tertyshnikova, S.2    Greco, C.R.3
  • 14
    • 33750601018 scopus 로고    scopus 로고
    • Upregulated expression of purinergic P2X7 receptor in Alzheimer disease and amyloid-β peptide-treated microglia and in peptide-injected rat hippocampus
    • McLarnon J.G., Ryu J.K., Walker D.G., et al. Upregulated expression of purinergic P2X7 receptor in Alzheimer disease and amyloid-β peptide-treated microglia and in peptide-injected rat hippocampus. J. Neuropathol. Exp. Neurol. 2006, 65:1090-1097.
    • (2006) J. Neuropathol. Exp. Neurol. , vol.65 , pp. 1090-1097
    • McLarnon, J.G.1    Ryu, J.K.2    Walker, D.G.3
  • 15
    • 56749085777 scopus 로고    scopus 로고
    • Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease
    • Ryu J.K., McLarnon J.G. Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease. Neuroreport 2008, 19:1715-1719.
    • (2008) Neuroreport , vol.19 , pp. 1715-1719
    • Ryu, J.K.1    McLarnon, J.G.2
  • 16
    • 77952746529 scopus 로고    scopus 로고
    • P2X7 receptor signaling pathway as a therapeutic target for neurodegenerative diseases
    • Takenouchi T., Sekiyama K., Sekigawa A., et al. P2X7 receptor signaling pathway as a therapeutic target for neurodegenerative diseases. Arch. Immunol. Ther. Exp. 2010, 58:91-96.
    • (2010) Arch. Immunol. Ther. Exp. , vol.58 , pp. 91-96
    • Takenouchi, T.1    Sekiyama, K.2    Sekigawa, A.3
  • 17
    • 34047110144 scopus 로고    scopus 로고
    • Therapeutic RNA interference for neurodegenerative diseases: from promise to progress
    • Gonzalez-Alegre P. Therapeutic RNA interference for neurodegenerative diseases: from promise to progress. Pharmacol. Ther. 2007, 114:34-55.
    • (2007) Pharmacol. Ther. , vol.114 , pp. 34-55
    • Gonzalez-Alegre, P.1
  • 18
    • 84862833670 scopus 로고    scopus 로고
    • Inhibition of Polo-like kinase 1 reduces amyloid-β-induced neuronal cell death in Alzheimer's disease
    • Song B., Davis K., Liu X.S., et al. Inhibition of Polo-like kinase 1 reduces amyloid-β-induced neuronal cell death in Alzheimer's disease. Aging (Albany NY) 2011, 3:846-851.
    • (2011) Aging (Albany NY) , vol.3 , pp. 846-851
    • Song, B.1    Davis, K.2    Liu, X.S.3
  • 19
    • 27744588007 scopus 로고    scopus 로고
    • Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model
    • Singer O., Marr R.A., Rockenstein E., et al. Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nat. Neurosci. 2005, 8:1343-1349.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1343-1349
    • Singer, O.1    Marr, R.A.2    Rockenstein, E.3
  • 20
    • 78349284376 scopus 로고    scopus 로고
    • The P2X7-egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia
    • Friedle S.A., Brautigam V.M., Nikodemova M., et al. The P2X7-egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia. Glia 2011, 59:1-13.
    • (2011) Glia , vol.59 , pp. 1-13
    • Friedle, S.A.1    Brautigam, V.M.2    Nikodemova, M.3
  • 21
    • 24744467358 scopus 로고    scopus 로고
    • Microglial phagocytosis induced by fibrillar amyloid-β and IgGs are differentially regulated by proinflammatory cytokines
    • Koenigsknecht-Talboo J., Landreth G.E. Microglial phagocytosis induced by fibrillar amyloid-β and IgGs are differentially regulated by proinflammatory cytokines. J. Neurosci. 2005, 25:8240-8249.
    • (2005) J. Neurosci. , vol.25 , pp. 8240-8249
    • Koenigsknecht-Talboo, J.1    Landreth, G.E.2
  • 22
    • 0037119422 scopus 로고    scopus 로고
    • Murphy, accelerated phagocytosis of amyloid-β by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor
    • Mitrasinovic O.M., Jr G.M. Murphy, accelerated phagocytosis of amyloid-β by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor. J. Biol. Chem. 2002, 277:29889-29896.
    • (2002) J. Biol. Chem. , vol.277 , pp. 29889-29896
    • Mitrasinovic, O.M.1    Murphy Jr., G.M.2
  • 23
    • 13144260638 scopus 로고    scopus 로고
    • Pharmacological analysis of cyclooxygenase-1 in inflammation
    • Smith C.J., Zhang Y., Koboldt C.M., et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc. Natl. Acad. Sci. USA 1998, 95:13313-13318.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13313-13318
    • Smith, C.J.1    Zhang, Y.2    Koboldt, C.M.3
  • 24
    • 20444430109 scopus 로고    scopus 로고
    • Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective COX-2 inhibitor
    • Parashar B., Latha Shankar S., O'Guin K., et al. Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective COX-2 inhibitor. J. Neurooncol. 2005, 71:141-148.
    • (2005) J. Neurooncol. , vol.71 , pp. 141-148
    • Parashar, B.1    Latha Shankar, S.2    O'Guin, K.3
  • 25
    • 0036398446 scopus 로고    scopus 로고
    • The IL-1 family and inflammatory diseases
    • Dinarello C.A. The IL-1 family and inflammatory diseases. Clin. Exp. Rheumatol. 2002, 20:S1-S13.
    • (2002) Clin. Exp. Rheumatol. , vol.20
    • Dinarello, C.A.1
  • 26
    • 37449011204 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1β in the murine brain
    • Mingam R., De Smedt V., Amedee T., et al. In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1β in the murine brain. Brain Behav. Immun. 2008, 22:234-244.
    • (2008) Brain Behav. Immun. , vol.22 , pp. 234-244
    • Mingam, R.1    De Smedt, V.2    Amedee, T.3
  • 27
    • 17144380506 scopus 로고    scopus 로고
    • Microglia lacking E prostanoid receptor subtype 2 have enhanced Aβ phagocytosis yet lack Aβ-activated neurotoxicity
    • Shie F.S., Breyer R.M., Montine T.J. Microglia lacking E prostanoid receptor subtype 2 have enhanced Aβ phagocytosis yet lack Aβ-activated neurotoxicity. Am. J. Pathol. 2005, 166:1163-1172.
    • (2005) Am. J. Pathol. , vol.166 , pp. 1163-1172
    • Shie, F.S.1    Breyer, R.M.2    Montine, T.J.3
  • 28
    • 0035866060 scopus 로고    scopus 로고
    • Amyloid-β stimulation of microglia and monocytes results in TNF-α-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
    • Combs C.K., Karlo J.C., Kao S.C., et al. Amyloid-β stimulation of microglia and monocytes results in TNF-α-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J. Neurosci. 2001, 21:1179-1188.
    • (2001) J. Neurosci. , vol.21 , pp. 1179-1188
    • Combs, C.K.1    Karlo, J.C.2    Kao, S.C.3
  • 29
    • 34247868178 scopus 로고    scopus 로고
    • Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain
    • Choi H.B., Ryu J.K., Kim S.U., et al. Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. J. Neurosci. 2007, 27:4957-4968.
    • (2007) J. Neurosci. , vol.27 , pp. 4957-4968
    • Choi, H.B.1    Ryu, J.K.2    Kim, S.U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.