메뉴 건너뛰기




Volumn 5, Issue 2, 2013, Pages 163-171

Omeprazole improves the anti-obesity and antidiabetic effects of exendin-4 in db/db mice

Author keywords

Diabetes; Exendin 4; Obesity; Omeprazole

Indexed keywords

EXENDIN 4; GASTRIN; GHRELIN; GLUCAGON; GLUCOKINASE; HEMOGLOBIN A1C; INSULIN; LEPTIN; OMEPRAZOLE;

EID: 84877029732     PISSN: 17530393     EISSN: 17530407     Source Type: Journal    
DOI: 10.1111/j.1753-0407.2012.00227.x     Document Type: Article
Times cited : (17)

References (37)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001; 414: 782-7.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 2
    • 0031972156 scopus 로고    scopus 로고
    • UKPDS 26: Sulphonylurea failure in non-insulin-dependent diabetic patients over six years. UK Prospective Diabetes Study (UKPDS) Group
    • Matthews DR, Cull CA, Stratton IM, Holman RR, Turner RC. UKPDS 26: Sulphonylurea failure in non-insulin-dependent diabetic patients over six years. UK Prospective Diabetes Study (UKPDS) Group. Diabet Med. 1998; 15: 297-303.
    • (1998) Diabet Med , vol.15 , pp. 297-303
    • Matthews, D.R.1    Cull, C.A.2    Stratton, I.M.3    Holman, R.R.4    Turner, R.C.5
  • 3
    • 40349088822 scopus 로고    scopus 로고
    • The epidemiology of obesity: The size of the problem
    • James WP. The epidemiology of obesity: The size of the problem. J Intern Med. 2008; 263: 336-52.
    • (2008) J Intern Med , vol.263 , pp. 336-352
    • James, W.P.1
  • 4
    • 79960262492 scopus 로고    scopus 로고
    • Management of type 2 diabetes: New and future developments in treatment
    • Tahrani AA, Bailey CJ, Del Prato S, Barnett AH. Management of type 2 diabetes: New and future developments in treatment. Lancet. 2011; 378: 182-97.
    • (2011) Lancet , vol.378 , pp. 182-197
    • Tahrani, A.A.1    Bailey, C.J.2    Del Prato, S.3    Barnett, A.H.4
  • 5
    • 0347360186 scopus 로고    scopus 로고
    • Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
    • Nielsen LL, Young AA, Parkes DG. Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept. 2004; 117: 77-88.
    • (2004) Regul Pept , vol.117 , pp. 77-88
    • Nielsen, L.L.1    Young, A.A.2    Parkes, D.G.3
  • 6
    • 65549112678 scopus 로고    scopus 로고
    • Exenatide: A review from pharmacology to clinical practice
    • Gentilella R, Bianchi C, Rossi A et al.Exenatide: A review from pharmacology to clinical practice. Diabetes Obes Metab. 2009; 11: 544-56.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 544-556
    • Gentilella, R.1    Bianchi, C.2    Rossi, A.3
  • 7
    • 0036310118 scopus 로고    scopus 로고
    • Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue
    • Rooman I, Lardon J, Bouwens L. Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue. Diabetes. 2002; 51: 686-90.
    • (2002) Diabetes , vol.51 , pp. 686-690
    • Rooman, I.1    Lardon, J.2    Bouwens, L.3
  • 8
    • 0027194337 scopus 로고
    • Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells
    • Wang TC, Bonner-Weir S, Oates PS et al.Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells. J Clin Invest. 1993; 92: 1349-56.
    • (1993) J Clin Invest , vol.92 , pp. 1349-1356
    • Wang, T.C.1    Bonner-Weir, S.2    Oates, P.S.3
  • 9
    • 64749100869 scopus 로고    scopus 로고
    • Effect of serum gastrin concentration on insulin resistance
    • Yoshihisa U, Susumu I, Yasuyuki M et al.Effect of serum gastrin concentration on insulin resistance. Digestion Absorption. 2006; 28: 42-5.
    • (2006) Digestion Absorption , vol.28 , pp. 42-45
    • Yoshihisa, U.1    Susumu, I.2    Yasuyuki, M.3
  • 10
    • 0028675939 scopus 로고
    • The consequences of hypergastrinemia
    • Creutzfeldt W. The consequences of hypergastrinemia. Yale J Biol Med. 1994; 67: 709-23.
    • (1994) Yale J Biol Med , vol.67 , pp. 709-723
    • Creutzfeldt, W.1
  • 11
    • 58149357117 scopus 로고    scopus 로고
    • Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice
    • Suarez-Pinzon WL, Power RF, Yan Y, Wasserfall C, Atkinson M, Rabinovitch A. Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice. Diabetes. 2008; 57: 3281-8.
    • (2008) Diabetes , vol.57 , pp. 3281-3288
    • Suarez-Pinzon, W.L.1    Power, R.F.2    Yan, Y.3    Wasserfall, C.4    Atkinson, M.5    Rabinovitch, A.6
  • 12
    • 0034960085 scopus 로고    scopus 로고
    • Effect of long-term, continuous versus alternate-day omeprazole therapy on serum gastrin in patients treated for reflux esophagitis
    • Ligumsky M, Lysy J, Siguencia G, Friedlander Y. Effect of long-term, continuous versus alternate-day omeprazole therapy on serum gastrin in patients treated for reflux esophagitis. J Clin Gastroenterol. 2001; 33: 32-5.
    • (2001) J Clin Gastroenterol , vol.33 , pp. 32-35
    • Ligumsky, M.1    Lysy, J.2    Siguencia, G.3    Friedlander, Y.4
  • 13
    • 67650685905 scopus 로고    scopus 로고
    • Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor restores normoglycaemia in non-obese diabetic mice
    • Suarez-Pinzon WL, Cembrowski GS, Rabinovitch A. Combination therapy with a dipeptidyl peptidase-4 inhibitor and a proton pump inhibitor restores normoglycaemia in non-obese diabetic mice. Diabetologia. 2009; 52: 1680-2.
    • (2009) Diabetologia , vol.52 , pp. 1680-1682
    • Suarez-Pinzon, W.L.1    Cembrowski, G.S.2    Rabinovitch, A.3
  • 14
    • 3042737844 scopus 로고    scopus 로고
    • Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4
    • Ogawa N, List JF, Habener JF, Maki T. Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes. 2004; 53: 1700-5.
    • (2004) Diabetes , vol.53 , pp. 1700-1705
    • Ogawa, N.1    List, J.F.2    Habener, J.F.3    Maki, T.4
  • 15
    • 3342908639 scopus 로고    scopus 로고
    • Metformin causes reduction of food intake and body weight gain and improvement of glucose intolerance in combination with dipeptidyl peptidase IV inhibitor in Zucker fa/fa rats
    • Yasuda N, Inoue T, Nagakura T et al.Metformin causes reduction of food intake and body weight gain and improvement of glucose intolerance in combination with dipeptidyl peptidase IV inhibitor in Zucker fa/fa rats. J Pharmacol Exp Ther. 2004; 310: 614-9.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 614-619
    • Yasuda, N.1    Inoue, T.2    Nagakura, T.3
  • 17
    • 0025827061 scopus 로고
    • 2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets
    • 2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets. J Biol Chem. 1991; 266: 9314-9.
    • (1991) J Biol Chem , vol.266 , pp. 9314-9319
    • Longo, E.A.1    Tornheim, K.2    Deeney, J.T.3
  • 18
    • 0023154010 scopus 로고
    • Factors underlying significant underestimations of glucokinase activity in crude liver extracts: Physiological implications of higher cellular activity
    • Davidson AL, Arion WJ. Factors underlying significant underestimations of glucokinase activity in crude liver extracts: Physiological implications of higher cellular activity. Arch Biochem Biophys. 1987; 253: 156-67.
    • (1987) Arch Biochem Biophys , vol.253 , pp. 156-167
    • Davidson, A.L.1    Arion, W.J.2
  • 19
    • 0032908654 scopus 로고    scopus 로고
    • Glucose-lowering and insulin-sensitizing actions of exendin-4: Studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)
    • Young AA, Gedulin BR, Bhavsar S et al.Glucose-lowering and insulin-sensitizing actions of exendin-4: Studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta). Diabetes. 1999; 48: 1026-34.
    • (1999) Diabetes , vol.48 , pp. 1026-1034
    • Young, A.A.1    Gedulin, B.R.2    Bhavsar, S.3
  • 20
    • 0036790520 scopus 로고    scopus 로고
    • The functions of leptin in nutrition, weight and physiology
    • Friedman JM. The functions of leptin in nutrition, weight and physiology. Nutr Rev. 2002; 60(Suppl.): S1-14.
    • (2002) Nutr Rev , vol.60 , Issue.SUPPL.
    • Friedman, J.M.1
  • 21
  • 22
    • 33845518516 scopus 로고    scopus 로고
    • Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation
    • Williams DL, Baskin DG, Schwartz MW. Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation. Diabetes. 2006; 55: 3387-93.
    • (2006) Diabetes , vol.55 , pp. 3387-3393
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 23
    • 34347406528 scopus 로고    scopus 로고
    • Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat
    • Bojanowska E, Nowak A. Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat. J Physiol Pharmacol. 2007; 58: 349-60.
    • (2007) J Physiol Pharmacol , vol.58 , pp. 349-360
    • Bojanowska, E.1    Nowak, A.2
  • 24
    • 0034218936 scopus 로고    scopus 로고
    • Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats
    • Al-Barazanji KA, Arch JR, Buckingham RE, Tadayyon M. Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats. Obes Res. 2000; 8: 317-23.
    • (2000) Obes Res , vol.8 , pp. 317-323
    • Al-Barazanji, K.A.1    Arch, J.R.2    Buckingham, R.E.3    Tadayyon, M.4
  • 25
    • 0034869583 scopus 로고    scopus 로고
    • Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats
    • Cui GL, Syversen U, Zhao CM, Chen D, Waldum HL. Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats. Scand J Gastroenterol. 2001; 36: 1011-5.
    • (2001) Scand J Gastroenterol , vol.36 , pp. 1011-1015
    • Cui, G.L.1    Syversen, U.2    Zhao, C.M.3    Chen, D.4    Waldum, H.L.5
  • 26
    • 0027981901 scopus 로고
    • Rat gastric somatostatin and gastrin release: Interactions of exendin-4 and truncated glucagon-like peptide-1 (GLP-1) amide
    • Eissele R, Bothe-Sandfort E, Göke B, Eng J, Arnold R, Koop H. Rat gastric somatostatin and gastrin release: Interactions of exendin-4 and truncated glucagon-like peptide-1 (GLP-1) amide. Life Sci. 1994; 55: 629-34.
    • (1994) Life Sci , vol.55 , pp. 629-634
    • Eissele, R.1    Bothe-Sandfort, E.2    Göke, B.3    Eng, J.4    Arnold, R.5    Koop, H.6
  • 27
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren AM, Small CJ, Ward HL et al.The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology. 2000; 141: 4325-8.
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3
  • 29
  • 30
    • 0036928761 scopus 로고    scopus 로고
    • High circulating ghrelin: a potential cause for hyperphagia and obesity in Prader-Willi syndrome
    • DelParigi A, Tschop M, Heiman ML et al.High circulating ghrelin: a potential cause for hyperphagia and obesity in Prader-Willi syndrome. J Clin Endocrinol Metab. 2002; 87: 5461-4.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5461-5464
    • DelParigi, A.1    Tschop, M.2    Heiman, M.L.3
  • 31
    • 84857045922 scopus 로고    scopus 로고
    • The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
    • Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR. The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide. Neuropharmacology. 2012; 62: 1916-27.
    • (2012) Neuropharmacology , vol.62 , pp. 1916-1927
    • Kanoski, S.E.1    Rupprecht, L.E.2    Fortin, S.M.3    De Jonghe, B.C.4    Hayes, M.R.5
  • 32
    • 84873743144 scopus 로고    scopus 로고
    • Additive feeding inhibitory and aversive effects of naltrexone and exendin-4 combinations
    • doi:10.1038/ijo.2012.16 (Epub ahead of print)
    • Liang NC, Bello NT, Moran TH. Additive feeding inhibitory and aversive effects of naltrexone and exendin-4 combinations. Intl J Obes. 2012. doi:10.1038/ijo.2012.16 (Epub ahead of print).
    • (2012) Intl J Obes
    • Liang, N.C.1    Bello, N.T.2    Moran, T.H.3
  • 33
    • 0242658765 scopus 로고    scopus 로고
    • Modulation of specific beta cell gene (re)expression during in vitro expansion of human pancreatic islet cells
    • Bouckenooghe T, Vandewalle B, Lukowiak B et al.Modulation of specific beta cell gene (re)expression during in vitro expansion of human pancreatic islet cells. Cell Transplant. 2003; 12: 799-807.
    • (2003) Cell Transplant , vol.12 , pp. 799-807
    • Bouckenooghe, T.1    Vandewalle, B.2    Lukowiak, B.3
  • 34
    • 18144435678 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice
    • Nakagawa T, Tsuchida A, Itakura Y et al.Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice. Diabetes. 2000; 49: 436-44.
    • (2000) Diabetes , vol.49 , pp. 436-444
    • Nakagawa, T.1    Tsuchida, A.2    Itakura, Y.3
  • 35
    • 70349768346 scopus 로고    scopus 로고
    • Exendin-4 regulates glucokinase expression by CaMKK/CaMKIV pathway in pancreatic beta-cell line
    • Murao K, Li J, Imachi H et al.Exendin-4 regulates glucokinase expression by CaMKK/CaMKIV pathway in pancreatic beta-cell line. Diabetes Obes Metab. 2009; 11: 939-46.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 939-946
    • Murao, K.1    Li, J.2    Imachi, H.3
  • 36
    • 0029147687 scopus 로고
    • Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with noninsulin-dependent diabetes mellitus: A randomized prospective 6-year study
    • Ohkubo Y, Kishikawa H, Araki E et al.Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with noninsulin-dependent diabetes mellitus: A randomized prospective 6-year study. Diabetes Res Clin Pract. 1995; 28: 103-17.
    • (1995) Diabetes Res Clin Pract , vol.28 , pp. 103-117
    • Ohkubo, Y.1    Kishikawa, H.2    Araki, E.3
  • 37
    • 84855656082 scopus 로고    scopus 로고
    • Proton pump inhibitor therapy associated with lower glycosylated hemoglobin levels in type 2 diabetes
    • Crouch MA, Mefford IN, Wade EU. Proton pump inhibitor therapy associated with lower glycosylated hemoglobin levels in type 2 diabetes. J Am Board Fam Med. 2012; 25: 50-4.
    • (2012) J Am Board Fam Med , vol.25 , pp. 50-54
    • Crouch, M.A.1    Mefford, I.N.2    Wade, E.U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.