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Volumn 37, Issue 2, 2013, Pages 272-278

Additive feeding inhibitory and aversive effects of naltrexone and exendin-4 combinations

Author keywords

combinational therapy; conditioned taste aversion; exendin 4; GLP 1; naltrexone; opioids

Indexed keywords

EXENDIN 4; NALTREXONE;

EID: 84873743144     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2012.16     Document Type: Article
Times cited : (21)

References (55)
  • 1
    • 67749129442 scopus 로고    scopus 로고
    • WHO March (accessed 26 September 2011)
    • WHO. Obesity and Overweight Factsheet. March, 2011, http://www.who.int/ mediacentre/factsheets/fs311/en/index.html (accessed 26 September 2011).
    • (2011) Obesity and Overweight Factsheet
  • 2
    • 77349106466 scopus 로고    scopus 로고
    • The surgical treatment of metabolic disease and morbid obesity
    • Fontana MA, Wohlgemuth SD. The surgical treatment of metabolic disease and morbid obesity. Gastroenterol Clin North Am 2010; 39: 125-133.
    • (2010) Gastroenterol Clin North Am , vol.39 , pp. 125-133
    • Fontana, M.A.1    Wohlgemuth, S.D.2
  • 4
    • 70349119432 scopus 로고    scopus 로고
    • The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: A systematic review and economic evaluation
    • iii-iv
    • Picot J, Jones J, Colquitt JL, Gospodarevskaya E, Loveman E, Baxter L et al. The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation. Health Technol Assess 2009; 13: 1-190, 215-357, iii-iv.
    • (2009) Health Technol Assess , vol.13 , Issue.1-190 , pp. 215-357
    • Picot, J.1    Jones, J.2    Colquitt, J.L.3    Gospodarevskaya, E.4    Loveman, E.5    Baxter, L.6
  • 5
    • 77953652112 scopus 로고    scopus 로고
    • Combination drugs for treating obesity
    • Greenway FL, Bray GA. Combination drugs for treating obesity. Curr Diab Rep 2010; 10: 108-115.
    • (2010) Curr Diab Rep , vol.10 , pp. 108-115
    • Greenway, F.L.1    Bray, G.A.2
  • 9
    • 0032540385 scopus 로고    scopus 로고
    • Molecular cloning of the helodermin and exendin-4 cDNAs in the lizard. Relationship to vasoactive intestinal polypeptide/pituitary adenylate cyclase activating polypeptide and glucagon-like peptide 1 and evidence against the existence of mammalian homologues
    • Pohl M, Wank SA. Molecular cloning of the helodermin and exendin-4 cDNAs in the lizard. Relationship to vasoactive intestinal polypeptide/pituitary adenylate cyclase activating polypeptide and glucagon-like peptide 1 and evidence against the existence of mammalian homologues. J Biol Chem 1998; 273: 9778-9784.
    • (1998) J Biol Chem , vol.273 , pp. 9778-9784
    • Pohl, M.1    Wank, S.A.2
  • 11
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C weight and cardiovascular risk factors over weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, Zhang B, Mac SM, Poon TH et al. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over weeks in 314 overweight patients with type 2 diabetes. Diabetes Obes Metab 2006; 8: 436-447.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3    Zhang, B.4    Mac, S.M.5    Poon, T.H.6
  • 12
    • 38549162147 scopus 로고    scopus 로고
    • Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
    • Klonoff DC, Buse JB, Nielsen LL, Guan X, Bowlus CL, Holcombe JH et al. Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years. Curr Med Res Opin 2008; 24: 275-286.
    • (2008) Curr Med Res Opin , vol.24 , pp. 275-286
    • Klonoff, D.C.1    Buse, J.B.2    Nielsen, L.L.3    Guan, X.4    Bowlus, C.L.5    Holcombe, J.H.6
  • 13
    • 0022538479 scopus 로고
    • An opioid antagonist, naltrexone, reduces preference for sucrose in humans
    • Fantino M, Hosotte J, Apfelbaum M. An opioid antagonist, naltrexone, reduces preference for sucrose in humans. Am J Physiol 1986; 251: R91-R96.
    • (1986) Am J Physiol , vol.251
    • Fantino, M.1    Hosotte, J.2    Apfelbaum, M.3
  • 15
    • 0030220787 scopus 로고    scopus 로고
    • Selective effects of naltrexone on food pleasantness and intake
    • Yeomans MR, Gray RW. Selective effects of naltrexone on food pleasantness and intake. Physiol Behav 1996; 60: 439-446.
    • (1996) Physiol Behav , vol.60 , pp. 439-446
    • Yeomans, M.R.1    Gray, R.W.2
  • 16
    • 0026606177 scopus 로고
    • Naltrexone-induced aversions: Assessment by place conditioning, taste reactivity, and taste avoidance paradigms
    • Parker LA, Rennie M. Naltrexone-induced aversions: assessment by place conditioning, taste reactivity, and taste avoidance paradigms. Pharmacol Biochem Behav 1992; 41: 559-565.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 559-565
    • Parker, L.A.1    Rennie, M.2
  • 17
    • 20044378930 scopus 로고    scopus 로고
    • Naltrexone for the treatment of alcoholism: A meta-analysis of randomized controlled trials
    • Srisurapanont M, Jarusuraisin N. Naltrexone for the treatment of alcoholism: a meta-analysis of randomized controlled trials. Int J Neuropsychopharmacol 2005; 8: 267-280.
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 267-280
    • Srisurapanont, M.1    Jarusuraisin, N.2
  • 19
    • 33644827166 scopus 로고    scopus 로고
    • Central gustatory lesions and learned taste aversions: Unconditioned stimuli
    • Mungarndee SS, Lundy Jr RF, Norgren R. Central gustatory lesions and learned taste aversions: unconditioned stimuli. Physiol Behav 2006; 87: 542-551.
    • (2006) Physiol Behav , vol.87 , pp. 542-551
    • Mungarndee, S.S.1    Lundy Jr., R.F.2    Norgren, R.3
  • 20
    • 0343035630 scopus 로고    scopus 로고
    • Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area
    • Scalera G, Grigson PS, Norgren R. Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area. Behav Neurosci 1997; 111: 633-645.
    • (1997) Behav Neurosci , vol.111 , pp. 633-645
    • Scalera, G.1    Grigson, P.S.2    Norgren, R.3
  • 21
    • 77956699440 scopus 로고    scopus 로고
    • Dose combinations of exendin-4 and salmon calcitonin produce additive and synergistic reductions in food intake in nonhuman primates
    • Bello NT, Kemm MH, Ofeldt EM, Moran TH. Dose combinations of exendin-4 and salmon calcitonin produce additive and synergistic reductions in food intake in nonhuman primates. Am J Physiol Regul Integr Comp Physiol 2010; 299: R945-R952.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Bello, N.T.1    Kemm, M.H.2    Ofeldt, E.M.3    Moran, T.H.4
  • 23
    • 77956176469 scopus 로고    scopus 로고
    • 'Weighing in' on synergy: Preclinical research on neurohormonal anti-obesity combinations
    • Roth JD, Trevaskis JL, Turek VF, Parkes DG. 'Weighing in' on synergy: preclinical research on neurohormonal anti-obesity combinations. Brain Res 2010; 1350: 86-94.
    • (2010) Brain Res , vol.1350 , pp. 86-94
    • Roth, J.D.1    Trevaskis, J.L.2    Turek, V.F.3    Parkes, D.G.4
  • 24
    • 54349121294 scopus 로고    scopus 로고
    • Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: Magnitude and mechanisms
    • Trevaskis JL, Coffey T, Cole R, Lei C, Wittmer C, Walsh B et al. Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms. Endocrinology 2008; 149: 5679-5687.
    • (2008) Endocrinology , vol.149 , pp. 5679-5687
    • Trevaskis, J.L.1    Coffey, T.2    Cole, R.3    Lei, C.4    Wittmer, C.5    Walsh, B.6
  • 25
    • 36348948599 scopus 로고    scopus 로고
    • Combination therapy with amylin and peptide YY[3-36] in obese rodents: Anorexigenic synergy and weight loss additivity
    • Roth JD, Coffey T, Jodka CM, Maier H, Athanacio JR, Mack CM et al. Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivity. Endocrinology 2007; 148: 6054-6061.
    • (2007) Endocrinology , vol.148 , pp. 6054-6061
    • Roth, J.D.1    Coffey, T.2    Jodka, C.M.3    Maier, H.4    Athanacio, J.R.5    MacK, C.M.6
  • 26
    • 77954216658 scopus 로고    scopus 로고
    • The application of drug dose equivalence in the quantitative analysis of receptor occupation and drug combinations
    • Tallarida RJ, Raffa RB. The application of drug dose equivalence in the quantitative analysis of receptor occupation and drug combinations. Pharmacol Ther 2010; 127: 165-174.
    • (2010) Pharmacol Ther , vol.127 , pp. 165-174
    • Tallarida, R.J.1    Raffa, R.B.2
  • 28
    • 77953728041 scopus 로고    scopus 로고
    • Preference or fat? Revisiting opioid effects on food intake
    • Taha SA. Preference or fat? Revisiting opioid effects on food intake. Physiol Behav 2010; 100: 429-437.
    • (2010) Physiol Behav , vol.100 , pp. 429-437
    • Taha, S.A.1
  • 29
    • 0033869532 scopus 로고    scopus 로고
    • Naltrexone administered to central nucleus of amygdala or PVN: Neural dissociation of diet and energy
    • Glass MJ, Billington CJ, Levine AS. Naltrexone administered to central nucleus of amygdala or PVN: neural dissociation of diet and energy. Am J Physiol Regul Integr Comp Physiol 2000; 279: R86-R92.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Glass, M.J.1    Billington, C.J.2    Levine, A.S.3
  • 32
    • 84856102513 scopus 로고    scopus 로고
    • GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake
    • Alhadeff AL, Rupprecht LE, Hayes MR. GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake. Endocrinology 2012; 153: 647-658.
    • (2012) Endocrinology , vol.153 , pp. 647-658
    • Alhadeff, A.L.1    Rupprecht, L.E.2    Hayes, M.R.3
  • 33
    • 80054035293 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake
    • Dossat AM, Lilly N, Kay K, Williams DL. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. J Neurosci 2011; 31: 14453-14457.
    • (2011) J Neurosci , vol.31 , pp. 14453-14457
    • Dossat, A.M.1    Lilly, N.2    Kay, K.3    Williams, D.L.4
  • 34
    • 79958267473 scopus 로고    scopus 로고
    • Optimizing outcomes for GLP-1 agonists
    • Freeman JS. Optimizing outcomes for GLP-1 agonists. J Am Osteopath Assoc 2011; 111: eS15-eS20.
    • (2011) J Am Osteopath Assoc , vol.111
    • Freeman, J.S.1
  • 35
    • 0022509255 scopus 로고
    • Cellular localization of proglucagon/glucagon-like peptide i messenger RNAs in rat brain
    • Han VK, Hynes MA, Jin C, Towle AC, Lauder JM, Lund PK. Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain. J Neurosci Res 1986; 16: 97-107.
    • (1986) J Neurosci Res , vol.16 , pp. 97-107
    • Han, V.K.1    Hynes, M.A.2    Jin, C.3    Towle, A.C.4    Lauder, J.M.5    Lund, P.K.6
  • 36
    • 0023266561 scopus 로고
    • Identification and localization of glucagonlike peptide-1 and its receptor in rat brain
    • Shimizu I, Hirota M, Ohboshi C, Shima K. Identification and localization of glucagonlike peptide-1 and its receptor in rat brain. Endocrinology 1987; 121: 1076-1082.
    • (1987) Endocrinology , vol.121 , pp. 1076-1082
    • Shimizu, I.1    Hirota, M.2    Ohboshi, C.3    Shima, K.4
  • 37
    • 0026521197 scopus 로고
    • Autoradiographic localization of receptors for glucagon-like peptide-1 7-36 amide in rat brain
    • Uttenthal LO, Toledano A, Blazquez E. Autoradiographic localization of receptors for glucagon-like peptide-1 (7-36) amide in rat brain. Neuropeptides 1992; 21: 143-146.
    • (1992) Neuropeptides , vol.21 , pp. 143-146
    • Uttenthal, L.O.1    Toledano, A.2    Blazquez, E.3
  • 38
    • 0042379840 scopus 로고    scopus 로고
    • Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus
    • Sarkar S, Fekete C, Legradi G, Lechan RM. Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Brain Res 2003; 985: 163-168.
    • (2003) Brain Res , vol.985 , pp. 163-168
    • Sarkar, S.1    Fekete, C.2    Legradi, G.3    Lechan, R.M.4
  • 39
    • 0036896243 scopus 로고    scopus 로고
    • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness
    • Kinzig KP, D'Alessio DA, Seeley RJ. The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 2002; 22: 10470-10476.
    • (2002) J Neurosci , vol.22 , pp. 10470-10476
    • Kinzig, K.P.1    D'Alessio, D.A.2    Seeley, R.J.3
  • 41
    • 0034652302 scopus 로고    scopus 로고
    • The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride
    • Seeley RJ, Blake K, Rushing PA, Benoit S, Eng J, Woods SC et al. The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride. J Neurosci 2000; 20: 1616-1621.
    • (2000) J Neurosci , vol.20 , pp. 1616-1621
    • Seeley, R.J.1    Blake, K.2    Rushing, P.A.3    Benoit, S.4    Eng, J.5    Woods, S.C.6
  • 42
    • 0032830989 scopus 로고    scopus 로고
    • Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus
    • Rinaman L. Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus. Am J Physiol 1999; 277: R582-R590.
    • (1999) Am J Physiol , vol.277
    • Rinaman, L.1
  • 43
    • 79960741385 scopus 로고    scopus 로고
    • Peripheral and central GLP-1 receptor populations mediate the anorectic effects of Peripherally administered GLP-1 receptor Agonists, liraglutide and exendin-4
    • Kanoski SE, Fortin SM, Arnold M, Grill HJ, Hayes MR. Peripheral and central GLP-1 receptor populations mediate the anorectic effects of Peripherally administered GLP-1 receptor Agonists, liraglutide and exendin-4. Endocrinology 2011; 152: 3103-3112.
    • (2011) Endocrinology , vol.152 , pp. 3103-3112
    • Kanoski, S.E.1    Fortin, S.M.2    Arnold, M.3    Grill, H.J.4    Hayes, M.R.5
  • 44
    • 63849248275 scopus 로고    scopus 로고
    • Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
    • Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009; 150: 1680-1687.
    • (2009) Endocrinology , vol.150 , pp. 1680-1687
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 45
    • 0028867442 scopus 로고
    • Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
    • Goke R, Larsen PJ, Mikkelsen JD, Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 1995; 7: 2294-2300.
    • (1995) Eur J Neurosci , vol.7 , pp. 2294-2300
    • Goke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 46
    • 0037349072 scopus 로고    scopus 로고
    • Entry of exendin-4 into brain is rapid but may be limited at high doses
    • Kastin AJ, Akerstrom V. Entry of exendin-4 into brain is rapid but may be limited at high doses. Int J Obes Relat Metab Disord 2003; 27: 313-318.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 313-318
    • Kastin, A.J.1    Akerstrom, V.2
  • 47
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • Hayes MR, Bradley L, Grill HJ. Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology 2009; 150: 2654-2659.
    • (2009) Endocrinology , vol.150 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 48
    • 62749153239 scopus 로고    scopus 로고
    • Pica as an adaptive response: Kaolin consumption helps rats recover from chemotherapy-induced illness
    • De Jonghe BC, Lawler MP, Horn CC, Tordoff MG. Pica as an adaptive response: Kaolin consumption helps rats recover from chemotherapy-induced illness. Physiol Behav 2009; 97: 87-90.
    • (2009) Physiol Behav , vol.97 , pp. 87-90
    • De Jonghe, B.C.1    Lawler, M.P.2    Horn, C.C.3    Tordoff, M.G.4
  • 49
    • 70449623336 scopus 로고    scopus 로고
    • Chemotherapy-induced kaolin intake is increased by lesion of the lateral parabrachial nucleus of the rat
    • Horn CC, De Jonghe BC, Matyas K, Norgren R. Chemotherapy-induced kaolin intake is increased by lesion of the lateral parabrachial nucleus of the rat. Am J Physiol Regul Integr Comp Physiol 2009; 297: R1375-R1382.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297
    • Horn, C.C.1    De Jonghe, B.C.2    Matyas, K.3    Norgren, R.4
  • 50
    • 33748118597 scopus 로고    scopus 로고
    • Antiobesity action of peripheral exenatide (exendin-4) in rodents: Effects on food intake, body weight, metabolic status and side-effect measures
    • Mack CM, Moore CX, Jodka CM, Bhavsar S, Wilson JK, Hoyt JA et al. Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures. Int J Obes (Lond) 2006; 30: 1332-1340.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1332-1340
    • MacK, C.M.1    Moore, C.X.2    Jodka, C.M.3    Bhavsar, S.4    Wilson, J.K.5    Hoyt, J.A.6
  • 52
    • 84873732811 scopus 로고    scopus 로고
    • The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
    • e-pub ahead of print 28 December 2011
    • Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR. The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide. Neuropharmacology 2011; e-pub ahead of print 28 December 2011.
    • (2011) Neuropharmacology
    • Kanoski, S.E.1    Rupprecht, L.E.2    Fortin, S.M.3    De Jonghe, B.C.4    Hayes, M.R.5
  • 53
    • 23844554610 scopus 로고    scopus 로고
    • Peripheral exendin-4 and peptide YY (3-36) synergistically reduce food intake through different mechanisms in mice
    • Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL. Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 2005; 146: 3748-3756.
    • (2005) Endocrinology , vol.146 , pp. 3748-3756
    • Talsania, T.1    Anini, Y.2    Siu, S.3    Drucker, D.J.4    Brubaker, P.L.5
  • 54
    • 34548390977 scopus 로고    scopus 로고
    • The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
    • Scott KA, Moran TH. The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size. Am J Physiol Regul Integr Comp Physiol 2007; 293: R983-R987.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Scott, K.A.1    Moran, T.H.2
  • 55
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2628-2635.
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6


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