An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice

Journal of Biological Chemistry

Volumn 288, Issue 17, 2013, Pages 11865-11876

  Daubeuf, François ^a   Hachet Haas, Muriel ^a   Gizzi, Patrick ^a   Gasparik, Vincent ^a   Bonnet, Dominique ^a   Utard, Valérie ^a   Hibert, Marcel ^a   Frossard, Nelly ^a   Galzi, Jean Luc ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC ASTHMA; CHEMOKINE RECEPTOR CXCR4; INFLAMMATORY CELLS; INTRAPERITONEAL ROUTE; KNOEVENAGEL REACTION; RAPID DEGRADATION; SMALL MOLECULES; SYSTEMIC CIRCULATION;

MOLECULES; TISSUE;

MAMMALS;

CHALCONE 4; CHALCONE DERIVATIVE; CYTOCHROME C OXIDASE; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DOSE RESPONSE; DRUG DEGRADATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG POTENCY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; EMBRYO; EOSINOPHIL; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMALS; ANTI-ASTHMATIC AGENTS; ASTHMA; CHALCONES; CHEMOKINE CXCL12; DRUG EVALUATION, PRECLINICAL; EOSINOPHILS; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED BALB C; RECEPTORS, CXCR4;

MUS;

EID: 84876943805     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.449348     Document Type: Article

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