-
1
-
-
0033779701
-
Calcineurin: Form and function
-
Rusnak, F., and, Mertz, P., (2000) Calcineurin: form and function. Physiol. Rev. 80, 1483-1521.
-
(2000)
Physiol. Rev.
, vol.80
, pp. 1483-1521
-
-
Rusnak, F.1
Mertz, P.2
-
2
-
-
0036015018
-
Dephosphorylation of tau protein by calcineurin triturated into neural living cells
-
DOI 10.1023/A:1015385527187
-
Wei, Q., Holzer, M., Brueckner, M. K., Liu, Y., and, Arendy, T., (2002) Dephosphorylation of tau protein by calcineurin (PP2B) led to neural living cells. Cell. Mol. Neurobiol. 22, 13-24. (Pubitemid 34579405)
-
(2002)
Cellular and Molecular Neurobiology
, vol.22
, Issue.1
, pp. 13-24
-
-
Wei, Q.1
Holzer, M.2
Brueckner, M.K.3
Liu, Y.4
Arendt, T.5
-
3
-
-
0034008234
-
Modulation of the phosphatase activity of calcineurin by oxidants and antioxidants in vitro
-
DOI 10.1046/j.1432-1327.2000.01240.x
-
Sommer, D., Fakata, K. L., Swanson, S. A., and, Stemmer, P. M., (2000) Modulation of the phosphatise activity of calcineurin by oxidants and antioxidants in vitro. Eur. J. Biochem. 267, 2312-2322. (Pubitemid 30220078)
-
(2000)
European Journal of Biochemistry
, vol.267
, Issue.8
, pp. 2312-2322
-
-
Sommer, D.1
Fakata, K.L.2
Swanson, S.A.3
Stemmer, P.M.4
-
4
-
-
0029759409
-
Superoxide dismutase protects calcineurin from inactivation
-
DOI 10.1038/383434a0
-
Wang, X., Culotta, V. C., and, Klee, C. B., (1996) Superoxide dismutase protects calcineurin from inactivation. Nature 383, 434-437. (Pubitemid 26330831)
-
(1996)
Nature
, vol.383
, Issue.6599
, pp. 434-437
-
-
Wang, X.1
Culotta, V.C.2
Klee, C.B.3
-
5
-
-
0033914937
-
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase
-
DOI 10.1046/j.1471-4159.2000.0750606.x
-
Ferri, A., Gabbianelli, R., Casciati, A., Paolucci, E., Rotilio, G., et al. (2000) Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase. J. Neurochem. 75, 606-613. (Pubitemid 30485441)
-
(2000)
Journal of Neurochemistry
, vol.75
, Issue.2
, pp. 606-613
-
-
Ferri, A.1
Gabbianelli, R.2
Casciati, A.3
Paolucci, E.4
Rotilio, G.5
Carri, M.T.6
-
6
-
-
35248837988
-
Renaming the DSCR1/Adapt78 gene family as RCAN: Regulators of calcineurin
-
DOI 10.1096/fj.06-7246com
-
Davies, K. J. A., Ermak, G., Rothermal, B. A., Pritchard, M., Heitman, J., et al. (2007). Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J. 21, 3023-3028. (Pubitemid 47565558)
-
(2007)
FASEB Journal
, vol.21
, Issue.12
, pp. 3023-3028
-
-
Davies, K.J.A.1
Ermak, G.2
Rothermel, B.A.3
Pritchard, M.4
Heitman, J.5
Ahnn, J.6
Henrique-Silva, F.7
Crawford, D.8
Canaider, S.9
Strippoli, P.10
Carinci, P.11
Min, K.-T.12
Fox, D.S.13
Cunningham, K.W.14
Bassel-Duby, R.15
Olson, E.N.16
Zhang, Z.17
Williams, R.S.18
Gerber, H.-P.19
Perez-Riba, M.20
Seo, H.21
Cao, X.22
Klee, C.B.23
Redondo, J.M.24
Maltais, L.J.25
Bruford, E.A.26
Povey, S.27
Molkentin, J.D.28
McKeon, F.D.29
Duh, E.J.30
Crabtree, G.R.31
Cyert, M.S.32
De La Luna, S.33
Estivill, X.34
more..
-
7
-
-
0035914413
-
Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease
-
Ermak, G., Morgan, T. E., and, Davies, K. J. A., (2001) Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease. J. Biol. Chem. 276, 38787-38794.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38787-38794
-
-
Ermak, G.1
Morgan, T.E.2
Davies, K.J.A.3
-
8
-
-
0031172775
-
Hamster adapt78 mRNA is a Down syndrome critical region homologue that is inducible by oxidative stress
-
DOI 10.1006/abbi.1997.0109
-
Crawford, D. R., Leahy, K. P., Abramova, N., Lan, L., Wang, Y., et al. (1997) Hamster adapt78 mRNA is a Down Syndrome critical region homologue that is inducible by oxidative stress. Arch. Biochem. Biophys. 342, 6-12. (Pubitemid 27217096)
-
(1997)
Archives of Biochemistry and Biophysics
, vol.342
, Issue.1
, pp. 6-12
-
-
Crawford, D.R.1
Leahy, K.P.2
Abramova, N.3
Lan, L.4
Wang, Y.5
Davies, K.J.A.6
-
9
-
-
10744226066
-
Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein
-
DOI 10.1016/S0891-5849(03)00358-7
-
Lin, H. Y., Michtalik, H. J., Zhang, S., Andersen, T. T., Van Riper, D. A., et al. (2003) Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein. Free Radic. Biol. Med. 35, 528-539. (Pubitemid 37289162)
-
(2003)
Free Radical Biology and Medicine
, vol.35
, Issue.5
, pp. 528-539
-
-
Lin, H.Y.1
Michtalik, H.J.2
Zhang, S.3
Andersen, T.T.4
Van Riper, D.A.5
Davies, K.K.J.A.6
Ermak, G.7
Petti, L.M.8
Nachod, S.9
Narayan, A.V.10
Bhatt, N.11
Crawford, D.R.12
-
10
-
-
24944484976
-
Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo
-
DOI 10.1073/pnas.0503846102
-
Chan, B., Greenan, G., McKeon, F., and, Ellenberger, T., (2005) Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo. Proc. Natl. Acad. Sci. 102, 13075-13080. (Pubitemid 41324981)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.37
, pp. 13075-13080
-
-
Chan, B.1
Greenan, G.2
McKeon, F.3
Ellenberger, T.4
-
11
-
-
0034708825
-
A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling
-
DOI 10.1074/jbc.275.12.8719
-
Rothermel, B., Vega, R. B., Yang, J., Wu, H., Bassel-Duby, R., et al. (2000). A protein encoded within the Down Syndrome Critical Region is enriched in striated muscles and inhibits calcineurin signaling. J. Biol. Chem. 275, 8719-8725. (Pubitemid 30180224)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.12
, pp. 8719-8725
-
-
Rothermel, B.1
Vega, R.B.2
Yang, J.3
Wu, H.4
Bassel-Duby, R.5
Williams, R.S.6
-
12
-
-
65549150814
-
The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators
-
Martinez-Martinez, S., Genesca, L., Rodriguez, A., Raya, A., Salichs, E., et al. (2009) The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators. Proc. Natl. Acad. Sci. 106, 6117-6122.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 6117-6122
-
-
Martinez-Martinez, S.1
Genesca, L.2
Rodriguez, A.3
Raya, A.4
Salichs, E.5
-
13
-
-
0347994896
-
The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning: Implications for mental retardation
-
DOI 10.1073/pnas.2536696100
-
Chang, K. T., Shi, Y. J., and, Min, K. T., (2003). The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning: implications for mental retardation. Proc. Natl. Acad. Sci. 100, 15794-15799. (Pubitemid 38021069)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.26
, pp. 15794-15799
-
-
Chang, K.T.1
Shi, Y.-J.2
Min, K.-T.3
-
14
-
-
1642291693
-
Aggregate formation and synaptic abnormality induced by DSCR1
-
Ma, H., Xiong, H., Liu, T., Zhang, L., Godzik, A., et al. (2004) Aggregate formation and synaptic abnormality induced by DSCR1. J. Neurochem. 88, 1485-1496. (Pubitemid 38366925)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.6
, pp. 1485-1496
-
-
Ma, H.1
Xiong, H.2
Liu, T.3
Zhang, L.4
Godzik, A.5
Zhang, Z.6
-
15
-
-
24644499539
-
Expression of calcipressin1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease
-
Cook, C. N., Hejna, M. J., Magnuson, D. J., and, Lee, J. M., (2005) Expression of calcipressin1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease. J. Alzheimers. Dis. 8, 63-73. (Pubitemid 41267325)
-
(2005)
Journal of Alzheimer's Disease
, vol.8
, Issue.1
, pp. 63-73
-
-
Cook, C.N.1
Hejna, M.J.2
Magnuson, D.J.3
Lee, J.M.4
-
16
-
-
41149154002
-
DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: Implications for Down syndrome and Alzheimer's disease
-
DOI 10.1093/hmg/ddm374
-
Keating, D. J., Dubach, D., Zanin, M. P., Yu, Y., Martin, K., et al. (2008) DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease. Hum. Mol. Genet. 17, 1020-1030. (Pubitemid 351426036)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.7
, pp. 1020-1030
-
-
Keating, D.J.1
Dubach, D.2
Zanin, M.P.3
Yu, Y.4
Martin, K.5
Zhao, Y.-F.6
Chen, C.7
Porta, S.8
Arbones, M.L.9
Mittaz, L.10
Pritchard, M.A.11
-
17
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu, J., Farmer, Jr. J. D., Lane, W. S., Friedman, J., Weissman, I., et al. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807-815. (Pubitemid 121001714)
-
(1991)
Cell
, vol.66
, Issue.4
, pp. 807-815
-
-
Liu, J.1
Farmer Jr., J.O.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
18
-
-
0035502342
-
Tissue Distribution of Calcineurin and its Sensitivity to Inhibition by Cyclosporine
-
DOI 10.1034/j.1600-6143.2001.10407.x
-
Kung, L., Batiuk, T. D., Palomo-Pinon, S., Noujaim, J., Helms, L. M. H., et al. (2001) Tissue distribution of calcineurin and its sensitivity to inhibition by cyclosporine. Am. J. Transplant. 1, 325-333. (Pubitemid 33681696)
-
(2001)
American Journal of Transplantation
, vol.1
, Issue.4
, pp. 325-333
-
-
Kung, L.1
Batiuk, T.D.2
Palomo-Pinon, S.3
Noujaim, J.4
Helms, L.M.H.5
Halloren, P.F.6
-
19
-
-
0034717317
-
Kinetic characterization of the nitric oxide toxicity for PC12 cells: Effect of half-life time of NO release
-
DOI 10.1016/S0014-2999(00)00244-2, PII S0014299900002442
-
Yamamoto, T., Yuyama, K., Nakamura, K., Kato, T., and, Yamamoto, H., (2000) Kinetic characterization of the nitric oxide toxicity for PC12 cells: effect of half-life time of no release. Eur. J. Pharmacol. 397, 25-33. (Pubitemid 30323807)
-
(2000)
European Journal of Pharmacology
, vol.397
, Issue.1
, pp. 25-33
-
-
Yamamoto, T.1
Yuyama, K.2
Nakamura, K.3
Kato, T.4
Yamamoto, H.5
-
20
-
-
33745684082
-
Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain
-
DOI 10.1080/15216540600791555, PII QR63518621G7228W
-
Yu, D. Y., Luo, J., Bu, F., Zhang, W., and, Wei, Q., (2006) Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatise activity in mouse brain. IUBMB Life 58: 429-433. (Pubitemid 43995628)
-
(2006)
IUBMB Life
, vol.58
, Issue.7
, pp. 429-433
-
-
Yu, D.-Y.1
Luo, J.2
Bu, F.3
Zhang, W.4
Wei, Q.5
-
21
-
-
35748960863
-
Brain expression of the calcineurin inhibitor RCAN1 (Adapt78)
-
DOI 10.1016/j.abb.2007.08.030, PII S0003986107004407
-
Mitchell, A. N., Jayakumar, L., Koleilat, I., Qian, J., Sheehan, C., et al. (2007) Brain expression of the calcineurin inhibitor RCAN1 (Adapt78). Arch. Biochem. Biophys. 467, 185-192. (Pubitemid 350050896)
-
(2007)
Archives of Biochemistry and Biophysics
, vol.467
, Issue.2
, pp. 185-192
-
-
Mitchell, A.N.1
Jayakumar, L.2
Koleilat, I.3
Qian, J.4
Sheehan, C.5
Bhoiwala, D.6
Hushmendy, S.F.7
Heuring, J.M.8
Crawford, D.R.9
-
22
-
-
0034881393
-
Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain
-
Serkova, N., Jacobsen, W., Niemann, C. U., Litt, L., Benet, L. Z., et al. (2001). Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain. Br. J. Pharmacol. 133, 875-885. (Pubitemid 32751797)
-
(2001)
British Journal of Pharmacology
, vol.133
, Issue.6
, pp. 875-885
-
-
Serkova, N.1
Jacobsen, W.2
Niemann, C.U.3
Litt, L.4
Benet, L.Z.5
Leibfritz, D.6
Christians, U.7
-
23
-
-
77955773133
-
Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function
-
Dohgu, S., Sumi, N., Nishioku, T., Takata, F., Watanabe, T., et al. (2010) Cyclosporin A induces hyperpermeability of the blood-brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function. Eur. J. Pharmacol. 644, 1-3.
-
(2010)
Eur. J. Pharmacol.
, vol.644
, pp. 1-3
-
-
Dohgu, S.1
Sumi, N.2
Nishioku, T.3
Takata, F.4
Watanabe, T.5
-
24
-
-
0025892034
-
Concentrations of cyclosporin A and its metabolites in human tissues postmortem
-
Lensmeyer, G. L., Wiebe, D. A., Carlson, I. H., and, Subramanian, R., (1991). Concentrations of cyclosporin A and its metabolites in human tissues postmortem. J. Anal. Toxicol. 15, 110-115.
-
(1991)
J. Anal. Toxicol.
, vol.15
, pp. 110-115
-
-
Lensmeyer, G.L.1
Wiebe, D.A.2
Carlson, I.H.3
Subramanian, R.4
-
25
-
-
0028856422
-
A new human gene from the Down Syndrome Critical Region encodes a proline-rich protein highly expressed in fetal brain and heart
-
Fuentes, J. J., Pritchard, M. A., Planas, A. M., Bosch, A., Ferrer, I., et al. (1995) A new human gene from the Down Syndrome Critical Region encodes a proline-rich protein highly expressed in fetal brain and heart. Hum. Mol. Genet. 4, 1935-1944.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1935-1944
-
-
Fuentes, J.J.1
Pritchard, M.A.2
Planas, A.M.3
Bosch, A.4
Ferrer, I.5
-
26
-
-
0033557724
-
Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway
-
Furuke, K., Shiraishi, M., Mostowski, H. S., and, Bloom, E. T., (1999) Fas ligand induction in human NK cells is regulated by redox through a calcineurin-nuclear factors of activated T cell-dependent pathway. J. Immunol. 162, 1988-1993. (Pubitemid 29288816)
-
(1999)
Journal of Immunology
, vol.162
, Issue.4
, pp. 1988-1993
-
-
Furuke, K.1
Shiraishi, M.2
Mostowski, H.S.3
Bloom, E.T.4
-
28
-
-
0030989834
-
Cyclosporine A-induced oxidative stress in rat hepatocytes
-
Wolf, A., Trendelenburg, C. F., Diez-Fernandez, C., Prieto, P., Houy, S., et al. (1997) Cyclosporine A-induced oxidative stress in rat hepatocytes. J. Pharmacol. Exp. Ther. 280, 1328-1334. (Pubitemid 27166730)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.280
, Issue.3
, pp. 1328-1334
-
-
Wolf, A.1
Trendelenburg, C.-F.2
Diez-Fernandez, C.3
Prieto, P.4
Houy, S.5
Trommer, W.E.6
Corder, A.7
-
29
-
-
33845946806
-
Black grape and garlic extracts protect against cyclosporine a nephrotoxicity
-
DOI 10.1080/08820130600745927, PII W60T0371N1162J27
-
Durak, I., Cetin, R., Candir, O., Devrim, E., Kilicoglu, B., et al. (2007) Black grape and garlic extracts protect against cyclosporine a nephrotoxicity. Immunol. Invest. 36, 105-114. (Pubitemid 46028422)
-
(2007)
Immunological Investigations
, vol.36
, Issue.1
, pp. 105-114
-
-
Durak, I.1
Cetin, R.2
Candir, O.3
Devrim, E.4
Kilicoglu, B.5
Avci, A.6
-
30
-
-
34447306022
-
RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: A potential pathogenic process in neurodegeneration
-
DOI 10.1093/hmg/ddm049
-
Porta, S., Serra, S. A., Huch, M., Valverde, M. A., Lloren, F., et al. (2007) RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration. Hum. Mol. Genet. 16, 1039-1050. (Pubitemid 47062725)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.9
, pp. 1039-1050
-
-
Porta, S.1
Serra, S.A.2
Huch, M.3
Valverde, M.A.4
Llorens, F.5
Estivill, X.6
Arbones, M.L.7
Marti, E.8
-
31
-
-
70349666552
-
Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways
-
Liu, H., Wang, P., Song, W. H., and, Sun, X. L., (2009). Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways. FASEB J. 23, 3383-3392.
-
(2009)
FASEB J.
, vol.23
, pp. 3383-3392
-
-
Liu, H.1
Wang, P.2
Song, W.H.3
Sun, X.L.4
-
32
-
-
41449086815
-
Calcineurin regulation in fungi and beyond
-
DOI 10.1128/EC.00326-07
-
Stie, J., and, Fox, D., (2008) Calcineurin regulation in fungi and beyond. Eukaryot. Cell 7, 177-186. (Pubitemid 351959685)
-
(2008)
Eukaryotic Cell
, vol.7
, Issue.2
, pp. 177-186
-
-
Stie, J.1
Fox, D.2
-
33
-
-
0031024092
-
The synergistic effects of cyclosporine and sirolimus
-
Kahan, B. D., (1997) The synergistic effects of cyclosporine and sirolimus. Transplantation 63, 170.
-
(1997)
Transplantation
, vol.63
, pp. 170
-
-
Kahan, B.D.1
-
34
-
-
52049122868
-
Kaempferol: A new immunosuppressant of calcineurin
-
Wang, H., Zhou, C. L., Lei, H., Zhang, S. D., Zheng, J. Q., et al. (2008) Kaempferol: a new immunosuppressant of calcineurin. IUBMB Life 60, 549-554.
-
(2008)
IUBMB Life
, vol.60
, pp. 549-554
-
-
Wang, H.1
Zhou, C.L.2
Lei, H.3
Zhang, S.D.4
Zheng, J.Q.5
-
35
-
-
0038007940
-
A compartmental pharmacokinetic model of cyclosporin and its predictive performance after Bayesian estimation in kidney and simultaneous pancreas-kidney transplant recipients
-
DOI 10.1093/ndt/gfg065
-
Cremers, S., Scholten, E. M., Schoemaker, R. C., Lentjes, E., Vermeij, P., et al. (2003) A compartmental pharmacokinetic model of cyclosporin and its predictive performance after Bayesian estimation in kidney and simultaneous pancreas-kidney transplant recipients. Nephrol. Dial. Transplant. 18, 1201-1208. (Pubitemid 36722525)
-
(2003)
Nephrology Dialysis Transplantation
, vol.18
, Issue.6
, pp. 1201-1208
-
-
Cremers, S.C.L.M.1
Scholten, E.M.2
Schoemaker, R.C.3
Lentjes, E.G.W.M.4
Vermeij, P.5
Paul, L.C.6
Den Hartigh, J.7
De Fijter, J.W.8
|