A human Dravet syndrome model from patient induced pluripotent stem cells

Molecular Brain

Volumn 6, Issue 1, 2013, Pages

  Higurashi, Norimichi ^a,b   Uchida, Taku ^a   Lossin, Christoph ^c   Misumi, Yoshio ^d   Okada, Yohei ^e   Akamatsu, Wado ^e   Imaizumi, Yoichi ^e   Zhang, Bo ^d   Nabeshima, Kazuki ^d   Mori, Masayuki X ^d   Katsurabayashi, Shutaro ^a   Shirasaka, Yukiyoshi ^f   Okano, Hideyuki ^e   Hirose, Shinichi ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f Shirasaka Clinic   (Japan)

Author keywords

Action potential; Disease modeling; Dravet syndrome; Epileptogenesis; Gamma aminobutyric acid; Induced pluripotent stem cells; Nav1.1; SCN1A

Indexed keywords

CYSTEINE; SODIUM CHANNEL NAV1.1; THREONINE;

ARTICLE; DEPOLARIZATION; FEMALE; GABAERGIC SYSTEM; GLUTAMATERGIC NERVE CELL; HUMAN; HUMAN TISSUE; NERVE CELL; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEWBORN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; SEVERE MYOCLONIC EPILEPSY IN INFANCY; SUBSTITUTION REACTION;

ACTION POTENTIALS; ADULT; CELL DIFFERENTIATION; EPILEPSIES, MYOCLONIC; FEMALE; GENES, REPORTER; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFANT; LENTIVIRUS; MODELS, BIOLOGICAL; NAV1.1 VOLTAGE-GATED SODIUM CHANNEL; NEURONS; PARVALBUMINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; YOUNG ADULT;

MURINAE;

EID: 84876839257     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-6-19     Document Type: Article

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