Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral-nerve injury: An advantageous alternative to ES and iPS cells

Journal of Cellular Biochemistry

Volumn 107, Issue 5, 2009, Pages 1016-1020

  Amoh, Yasuyuki ^a   Kanoh, Maho ^a   Niiyama, Shiro ^a   Hamada, Yuko ^a   Kawahara, Katsumasa ^a   Sato, Yuichi ^b   Hoffman, Robert M ^c,d   Katsuoka, Kensei ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c ANTICANCER INC   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Hair follicle; Nestin; Peripheral nerve; Pluripotency; Regeneration; Regenerative medicine; Stem cells; Transplantation

Indexed keywords

CYTOKERATIN 15; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ELECTROSTIMULATION; GLIA CELL; HAIR FOLLICLE; HAIR FOLLICLE PLURIPOTENT STEM CELL; HISTOPATHOLOGY; KERATINOCYTE; MELANOCYTE; MOUSE; NERVE CELL; NERVE REGENERATION; NONHUMAN; NUDE MOUSE; PERIPHERAL NERVE INJURY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SCHWANN CELL; SCIATIC NERVE; SMOOTH MUSCLE FIBER; STEM CELL TRANSPLANTATION;

ANIMALS; CELL PROLIFERATION; EMBRYONIC STEM CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HAIR FOLLICLE; HUMANS; MICE; NERVE REGENERATION; PLURIPOTENT STEM CELLS; SCIATIC NERVE;

IPS;

EID: 67749137298     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22204     Document Type: Article

References (15)

1. Amoh Y, Li L, Katsuoka K, Penman S, Hoffman RM. 2005a. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons. Proc Natl Acad Sci USA 102: 5530-5534.
2. Amoh Y, Li L, Campillo R, Kawahara K, Katsuoka K, Penman S, Hoffman RM. 2005b. Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves. Proc Natl Acad Sci USA 102:17734-17738.
3. Amoh Y, Li L, Katsuoka K, Hoffman RM. 2008. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function. Cell Cycle 7:1865-1869.
4. Amoh Y, Kanoh M, Niiyama S, Kawahara K, Sato Y, Katsuoka K, Hoffman RM. 2009. Human and mouse hair follicles contain both multipotent and monopotent stem cells. Cell Cycle 8: 176-177.
5. Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K. 2009. Virusfree induction of pluripotency and subsequent excision of reprogramming factors. Nature 458: 771-775.
6. Li L, Mignone J, Yang M, Matic M, Penman S, Enikolopov G, Hoffman RM. 2003. Nestin expression in hair follicle sheath progenitor cells. Proc Natl Acad Sci USA 100:9958-9961.
7. Mignone JL, Kukekov V, Chiang AS, Steindler D, Enikolopov G. 2004. Neural stem and progenitor cells in nestin-GFP transgenic mice. J Comp Neurol 469:311-324.
8. Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N, Yamanaka S. 2008. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26:101-106.
9. Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S. 2008. Generation of mouse induced pluripotent stem cells without viral vectors. Science 322: 949-953.
10. Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A, Yamaguchi M, Mori K, Goldman SA, Itakura T, Okano H. 2001. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci 21:3895-3903.
11. Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R. 2009. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136:964-977.
12. Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
13. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282:1145-1147.
14. Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hamalainen R, Cowling R, Wang W, Liu P, Gertsenstein M, Kaji K, Sung H-K, Nagy A. 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458: 766-770.
15. Yu H, Fang D, Kumar SM, Li L, Nguyen TK, Acs G, Herlyn M, Xu X. 2006. Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am J Pathol 168: 1879-1888.