Cyclooxygenase-2 inhibits T helper cell type 9 differentiation during allergic lung inflammation via down-regulation of IL-17RB

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 8, 2013, Pages 812-822

  Li, Hong ^a   Edin, Matthew L ^a   Bradbury, J Alyce ^a   Graves, Joan P ^a   DeGraff, Laura M ^a   Gruzdev, Artiom ^a   Cheng, Jennifer ^a   Dackor, Ryan T ^a   Wang, Ping Ming ^b   Bortner, Carl D ^a,b   Garantziotis, Stavros ^a   Jetten, Anton M ^a   Zeldin, Darryl C ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Asthma; Cyclooxygenase 2; IL 17RB; Prostaglandins; T helper cell type 9 cells

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ICOSANOID; INTERLEUKIN 10; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR B; INTERLEUKIN 4; INTERLEUKIN 9; PROSTAGLANDIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RESPONSE; FLOW CYTOMETRY; GENE SILENCING; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LUNG LAVAGE; LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; ASTHMA; CYCLOOXYGENASE 2 INHIBITORS; CYTOKINES; EICOSANOIDS; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; INFLAMMATION; LUNG; MALE; MICE; MICROSCOPY, CONFOCAL; MODELS, ANIMAL; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-17; T-LYMPHOCYTE SUBSETS;

EID: 84876836406     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201211-2073OC     Document Type: Article

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