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Volumn 12, Issue 5, 2013, Pages 761-774

The transcriptional response of cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary adaptation to the mammalian host

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TRANSCRIPTOME;

EID: 84876835512     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00073-13     Document Type: Article
Times cited : (62)

References (62)
  • 1
    • 0025175621 scopus 로고
    • Ecology, life cycle, and infectious propagule of Cryptococcus neoformans
    • Ellis DH, Pfeiffer TJ. 1990. Ecology, life cycle, and infectious propagule of Cryptococcus neoformans. Lancet 336:923-925.
    • (1990) Lancet , vol.336 , pp. 923-925
    • Ellis, D.H.1    Pfeiffer, T.J.2
  • 3
    • 80052582060 scopus 로고    scopus 로고
    • Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans
    • 9 August. doi:10.1128/mBio.00158-11
    • Alanio A, Desnos-Ollivier M, Dromer F. 9 August 2011. Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans. mBio 2(4):e00158-11. doi:10.1128/mBio.00158-11.
    • (2011) mBio , vol.2 , Issue.4
    • Alanio, A.1    Desnos-Ollivier, M.2    Dromer, F.3
  • 4
    • 23844483451 scopus 로고    scopus 로고
    • Cryptococcus neoformans gene expression during murine macrophage infection
    • Fan W, Kraus PR, Boily MJ, Heitman J. 2005. Cryptococcus neoformans gene expression during murine macrophage infection. Eukaryot. Cell 4:1420-1433.
    • (2005) Eukaryot. Cell , vol.4 , pp. 1420-1433
    • Fan, W.1    Kraus, P.R.2    Boily, M.J.3    Heitman, J.4
  • 6
    • 0033931999 scopus 로고    scopus 로고
    • Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection
    • Feldmesser M, Kress Y, Novikoff P, Casadevall A. 2000. Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection. Infect. Immun. 68:4225-4237.
    • (2000) Infect. Immun. , vol.68 , pp. 4225-4237
    • Feldmesser, M.1    Kress, Y.2    Novikoff, P.3    Casadevall, A.4
  • 8
    • 0035370561 scopus 로고    scopus 로고
    • Intracellular parasitism of macrophages by Cryptococcus neoformans
    • Feldmesser M, Tucker S, Casadevall A. 2001. Intracellular parasitism of macrophages by Cryptococcus neoformans. Trends Microbiol. 9:273-278.
    • (2001) Trends Microbiol. , vol.9 , pp. 273-278
    • Feldmesser, M.1    Tucker, S.2    Casadevall, A.3
  • 9
    • 0036165063 scopus 로고    scopus 로고
    • A phagosome of one's own: A microbial guide to life in the macrophage
    • Amer AO, Swanson MS. 2002. A phagosome of one's own: a microbial guide to life in the macrophage. Curr. Opin. Microbiol. 5:56-61.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 56-61
    • Amer, A.O.1    Swanson, M.S.2
  • 10
    • 0036777063 scopus 로고    scopus 로고
    • Life and death in a macrophage: Role of the glyoxylate cycle in virulence
    • Lorenz MC, Fink GR. 2002. Life and death in a macrophage: role of the glyoxylate cycle in virulence. Eukaryot. Cell 1:657-662.
    • (2002) Eukaryot. Cell , vol.1 , pp. 657-662
    • Lorenz, M.C.1    Fink, G.R.2
  • 11
    • 1542674589 scopus 로고    scopus 로고
    • Immunity to fungal infections
    • Romanini L. 2004. Immunity to fungal infections. Nat. Rev. Immunol. 4:1-23.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 1-23
    • Romanini, L.1
  • 12
    • 0035909926 scopus 로고    scopus 로고
    • Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages
    • Steenbergen JN, Shuman HA, Casadevall A. 2001. Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc. Natl. Acad. Sci. U. S. A. 98:15245-15250.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 15245-15250
    • Steenbergen, J.N.1    Shuman, H.A.2    Casadevall, A.3
  • 13
    • 0038054472 scopus 로고    scopus 로고
    • The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans
    • Steenbergen JN, Casadevall A. 2003. The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans. Microbes Infect. 5:667-675.
    • (2003) Microbes Infect. , vol.5 , pp. 667-675
    • Steenbergen, J.N.1    Casadevall, A.2
  • 14
    • 0043197395 scopus 로고    scopus 로고
    • 'Ready made' virulence and 'dual use' virulence factors in pathogenic environmental fungi-the Cryptococcus neoformans paradigm
    • Casadevall A, Steenbergen JN, Nosanchuk JD. 2003. 'Ready made' virulence and 'dual use' virulence factors in pathogenic environmental fungi-the Cryptococcus neoformans paradigm. Curr. Opin. Microbiol. 6:332-337.
    • (2003) Curr. Opin. Microbiol. , vol.6 , pp. 332-337
    • Casadevall, A.1    Steenbergen, J.N.2    Nosanchuk, J.D.3
  • 15
    • 0041823555 scopus 로고    scopus 로고
    • Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum
    • Steenbergen JN, Nosanchuk JD, Malliaris SD, Casadevall A. 2003. Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoideum. Infect. Immun. 71:4862-4872.
    • (2003) Infect. Immun. , vol.71 , pp. 4862-4872
    • Steenbergen, J.N.1    Nosanchuk, J.D.2    Malliaris, S.D.3    Casadevall, A.4
  • 16
    • 52949114243 scopus 로고    scopus 로고
    • Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
    • Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, Noble SM. 2008. Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 135:174-188.
    • (2008) Cell , vol.135 , pp. 174-188
    • Liu, O.W.1    Chun, C.D.2    Chow, E.D.3    Chen, C.4    Madhani, H.D.5    Noble, S.M.6
  • 18
    • 70449703215 scopus 로고    scopus 로고
    • An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers
    • Kim MS, Kim SY, Yoon JK, Lee YW, Bahn YS. 2009. An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers. Biochem. Biophys. Res. Commun. 390:983-988.
    • (2009) Biochem. Biophys. Res. Commun. , vol.390 , pp. 983-988
    • Kim, M.S.1    Kim, S.Y.2    Yoon, J.K.3    Lee, Y.W.4    Bahn, Y.S.5
  • 21
    • 0031020229 scopus 로고    scopus 로고
    • Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans
    • Chen SC, Wright LC, Santangelo RT, Muller M, Moran VR, Kuchel PW, Sorrell TC. 1997. Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans. Infect. Immun. 65:405-411.
    • (1997) Infect. Immun. , vol.65 , pp. 405-411
    • Chen, S.C.1    Wright, L.C.2    Santangelo, R.T.3    Muller, M.4    Moran, V.R.5    Kuchel, P.W.6    Sorrell, T.C.7
  • 22
    • 0028040050 scopus 로고
    • Regulation of mannitol biosynthesis and degradation by Cryptococcus neoformans
    • Niehaus WG, Flynn T. 1994. Regulation of mannitol biosynthesis and degradation by Cryptococcus neoformans. J. Bacteriol. 176:651-655.
    • (1994) J. Bacteriol. , vol.176 , pp. 651-655
    • Niehaus, W.G.1    Flynn, T.2
  • 23
    • 0031568071 scopus 로고    scopus 로고
    • Effect of serum IgG1 to Cryptococcus neoformans glucuronoxylomannan on murine pulmonary infection
    • Feldmesser M, Casadevall A. 1997. Effect of serum IgG1 to Cryptococcus neoformans glucuronoxylomannan on murine pulmonary infection. J. Immunol. 158:790-799.
    • (1997) J. Immunol. , vol.158 , pp. 790-799
    • Feldmesser, M.1    Casadevall, A.2
  • 24
    • 84857099099 scopus 로고    scopus 로고
    • Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection
    • doi:10.1371/journal.pone.0024485
    • García-Rodas R, Casadevall A, Rodríguez-Tudela JL, Cuenca-Estrella M, Zaragoza O. 2011. Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection. PLoS One 6:e24485. doi:10.1371/journal.pone.0024485.
    • (2011) PLoS One , vol.6
    • García-Rodas, R.1    Casadevall, A.2    Rodríguez-Tudela, J.L.3    Cuenca-Estrella, M.4    Zaragoza, O.5
  • 25
    • 33750604745 scopus 로고    scopus 로고
    • Expulsion of live pathogenic yeast by macrophages
    • Ma H, Croudace JE, Lammas DA, May RC. 2006. Expulsion of live pathogenic yeast by macrophages. Curr. Biol. 16:2156-2160.
    • (2006) Curr. Biol. , vol.16 , pp. 2156-2160
    • Ma, H.1    Croudace, J.E.2    Lammas, D.A.3    May, R.C.4
  • 26
    • 33750606979 scopus 로고    scopus 로고
    • Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages
    • Alvarez M, Casadevall A. 2006. Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages. Curr. Biol. 16:2161-2165.
    • (2006) Curr. Biol. , vol.16 , pp. 2161-2165
    • Alvarez, M.1    Casadevall, A.2
  • 28
    • 84555195193 scopus 로고    scopus 로고
    • Amoeba provides insight into the origin of virulence in pathogenic fungi
    • Casadevall A. 2012. Amoeba provides insight into the origin of virulence in pathogenic fungi. Adv. Exp. Med. Biol. 710:1-10.
    • (2012) Adv. Exp. Med. Biol. , vol.710 , pp. 1-10
    • Casadevall, A.1
  • 29
    • 0018725667 scopus 로고
    • Cryptococcus neoformans: Gastronomic delight of a soil ameba
    • Bunting LA, Neilson JB, Bulmer GS. 1979. Cryptococcus neoformans: gastronomic delight of a soil ameba. Sabouraudia 17:225-232.
    • (1979) Sabouraudia , vol.17 , pp. 225-232
    • Bunting, L.A.1    Neilson, J.B.2    Bulmer, G.S.3
  • 30
    • 84907124026 scopus 로고
    • Control of Cryptococcus neoformans in nature by biotic factors
    • Ruiz A, Neilson JB, Bulmer GS. 1982. Control of Cryptococcus neoformans in nature by biotic factors. Sabouraudia 20:21-29.
    • (1982) Sabouraudia , vol.20 , pp. 21-29
    • Ruiz, A.1    Neilson, J.B.2    Bulmer, G.S.3
  • 31
    • 79958076329 scopus 로고    scopus 로고
    • Phospholipids trigger Cryptococcus neoformans capsular enlargement during interactions with amoebae and macrophages
    • doi:10.1371/journal.ppat.1002047
    • Chrisman CJ, Albuquerque P, Guimaraes AJ, Nieves E, Casadevall A. 2011. Phospholipids trigger Cryptococcus neoformans capsular enlargement during interactions with amoebae and macrophages. PLoS Pathog. 7:e1002047. doi:10.1371/journal.ppat.1002047.
    • (2011) PLoS Pathog. , vol.7
    • Chrisman, C.J.1    Albuquerque, P.2    Guimaraes, A.J.3    Nieves, E.4    Casadevall, A.5
  • 33
    • 0035811478 scopus 로고    scopus 로고
    • The glyoxylate cycle is required for fungal virulence
    • Lorenz MC, Fink GR. 2001. The glyoxylate cycle is required for fungal virulence. Nature 412:83-86.
    • (2001) Nature , vol.412 , pp. 83-86
    • Lorenz, M.C.1    Fink, G.R.2
  • 35
    • 6344285788 scopus 로고    scopus 로고
    • Transcriptional response of Candida albicans upon internalization by macrophages
    • Lorenz MC, Bender JA, Fink GR. 2004. Transcriptional response of Candida albicans upon internalization by macrophages. Eukaryot. Cell 3:1076-1087.
    • (2004) Eukaryot. Cell , vol.3 , pp. 1076-1087
    • Lorenz, M.C.1    Bender, J.A.2    Fink, G.R.3
  • 37
    • 50049125079 scopus 로고    scopus 로고
    • Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection
    • Hu G, Cheng PY, Sham A, Perfect JR, Kronstad JW. 2008. Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection. Mol. Microbiol. 69:1456-1475.
    • (2008) Mol. Microbiol. , vol.69 , pp. 1456-1475
    • Hu, G.1    Cheng, P.Y.2    Sham, A.3    Perfect, J.R.4    Kronstad, J.W.5
  • 38
    • 0014374760 scopus 로고
    • Production of D-mannitol and glycerol by yeasts
    • Onishi H, Suzuki T. 1968. Production of D-mannitol and glycerol by yeasts. Appl. Microbiol. 16:1847-1852.
    • (1968) Appl. Microbiol. , vol.16 , pp. 1847-1852
    • Onishi, H.1    Suzuki, T.2
  • 39
    • 0025290785 scopus 로고
    • Production of the hexitol D-mannitol by Cryptococcus neoformans in vitro and in rabbits with experimental meningitis
    • Wong B, Perfect JR, Beggs S, Wright KA. 1990. Production of the hexitol D-mannitol by Cryptococcus neoformans in vitro and in rabbits with experimental meningitis. Infect. Immun. 58:1664-1670.
    • (1990) Infect. Immun. , vol.58 , pp. 1664-1670
    • Wong, B.1    Perfect, J.R.2    Beggs, S.3    Wright, K.A.4
  • 40
    • 0029988469 scopus 로고    scopus 로고
    • Stress tolerance and pathogenic potential of a mannitol mutant of Cryptococcus neoformans
    • Chaturvedi V, Flynn T, Niehaus WG, Wong B. 1996. Stress tolerance and pathogenic potential of a mannitol mutant of Cryptococcus neoformans. Microbiology 142:937-943.
    • (1996) Microbiology , vol.142 , pp. 937-943
    • Chaturvedi, V.1    Flynn, T.2    Niehaus, W.G.3    Wong, B.4
  • 43
    • 40649109347 scopus 로고    scopus 로고
    • Upregulation of glyoxylate cycle genes upon Paracoccidioides brasiliensis internalization by murine macrophages and in vitro nutritional stress condition
    • Derengowski LS, Tavares AH, Silva S, Procópio LS, Felipe MS, Silva-Pereira I. 2008. Upregulation of glyoxylate cycle genes upon Paracoccidioides brasiliensis internalization by murine macrophages and in vitro nutritional stress condition. Med. Mycol. 46:125-134.
    • (2008) Med. Mycol. , vol.46 , pp. 125-134
    • Derengowski, L.S.1    Tavares, A.H.2    Silva, S.3    Procópio, L.S.4    Felipe, M.S.5    Silva-Pereira, I.6
  • 45
    • 10444242473 scopus 로고    scopus 로고
    • Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans
    • Giles SS, Perfect JR, Cox GM. 2005. Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans. Fungal Genet. Biol. 42:20-29.
    • (2005) Fungal Genet. Biol. , vol.42 , pp. 20-29
    • Giles, S.S.1    Perfect, J.R.2    Cox, G.M.3
  • 46
    • 13844316982 scopus 로고    scopus 로고
    • Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans
    • Missall TA, Lodge JK. 2005. Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans. Eukaryot. Cell 4:487-489.
    • (2005) Eukaryot. Cell , vol.4 , pp. 487-489
    • Missall, T.A.1    Lodge, J.K.2
  • 47
    • 0035831532 scopus 로고    scopus 로고
    • Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast: Evidence for a signaling pathway from the mitochondrial genome to the nucleus
    • Dagsgaard C, Taylor LE, O'Brien KM, Poyton RO. 2001. Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast: evidence for a signaling pathway from the mitochondrial genome to the nucleus. J. Biol. Chem. 276:7593-7601.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7593-7601
    • Dagsgaard, C.1    Taylor, L.E.2    O'Brien, K.M.3    Poyton, R.O.4
  • 48
    • 0038705053 scopus 로고    scopus 로고
    • Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment
    • Toffaletti DL, Del Poeta M, Rude TH, Dietrich F, Perfect JR. 2003. Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment. Microbiology 149:1041-1049.
    • (2003) Microbiology , vol.149 , pp. 1041-1049
    • Toffaletti, D.L.1    Del Poeta, M.2    Rude, T.H.3    Dietrich, F.4    Perfect, J.R.5
  • 49
    • 51149123638 scopus 로고    scopus 로고
    • Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth
    • Li AH, Lam WL, Stokes RW. 2008. Characterization of genes differentially expressed within macrophages by virulent and attenuated Mycobacterium tuberculosis identifies candidate genes involved in intracellular growth. Microbiology 154:2291-2303.
    • (2008) Microbiology , vol.154 , pp. 2291-2303
    • Li, A.H.1    Lam, W.L.2    Stokes, R.W.3
  • 50
    • 0023877466 scopus 로고
    • Influence of oxygen tension on the respiratory activity of Mycobacterium phlei
    • Gillespie J, Barton LL, Rypka EW. 1988. Influence of oxygen tension on the respiratory activity of Mycobacterium phlei. J. Gen. Microbiol. 134: 247-252.
    • (1988) J. Gen. Microbiol. , vol.134 , pp. 247-252
    • Gillespie, J.1    Barton, L.L.2    Rypka, E.W.3
  • 51
    • 0742304300 scopus 로고    scopus 로고
    • The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi
    • Gancedo C, Flores CL. 2004. The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi. FEMS Yeast Res. 4:351-359.
    • (2004) FEMS Yeast Res. , vol.4 , pp. 351-359
    • Gancedo, C.1    Flores, C.L.2
  • 52
    • 0036267206 scopus 로고    scopus 로고
    • Disruption in Candida albicans of the TPS2 gene encoding trehalose-6-phosphate phosphatase affects cell integrity and decreases infectivity
    • Zaragoza O, de Virgilio C, Pontón J, Gancedo C. 2002. Disruption in Candida albicans of the TPS2 gene encoding trehalose-6-phosphate phosphatase affects cell integrity and decreases infectivity. Microbiology 148: 1281-1290.
    • (2002) Microbiology , vol.148 , pp. 1281-1290
    • Zaragoza, O.1    de Virgilio, C.2    Pontón, J.3    Gancedo, C.4
  • 53
    • 33749254466 scopus 로고    scopus 로고
    • Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans
    • Petzold EW, Himmelreich U, Mylonakis E, Rude T, Toffaletti D, Cox GM, Miller JL, Perfect JR. 2006. Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans. Infect. Immun. 74:5877-5887.
    • (2006) Infect. Immun. , vol.74 , pp. 5877-5887
    • Petzold, E.W.1    Himmelreich, U.2    Mylonakis, E.3    Rude, T.4    Toffaletti, D.5    Cox, G.M.6    Miller, J.L.7    Perfect, J.R.8
  • 55
    • 0023649963 scopus 로고
    • Rapid changes of heat and desiccation tolerance correlated with changes of trehalose content in Saccharomyces cerevisiae cells subjected to temperature shifts
    • Hottiger T, Boller T, Wiemken A. 1987. Rapid changes of heat and desiccation tolerance correlated with changes of trehalose content in Saccharomyces cerevisiae cells subjected to temperature shifts. FEBS Lett. 220: 113-115.
    • (1987) FEBS Lett. , vol.220 , pp. 113-115
    • Hottiger, T.1    Boller, T.2    Wiemken, A.3
  • 56
    • 4644236078 scopus 로고    scopus 로고
    • Role of trehalose phosphate synthase and trehalose during hypoxia: From flies to mammals
    • Chen Q, Haddad GG. 2004. Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals. J. Exp. Biol. 207:3125-3129.
    • (2004) J. Exp. Biol. , vol.207 , pp. 3125-3129
    • Chen, Q.1    Haddad, G.G.2
  • 57
    • 0142248154 scopus 로고    scopus 로고
    • Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae
    • Rosenfeld E, Beauvoit B. 2003. Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae. Yeast 20: 1115-1144.
    • (2003) Yeast , vol.20 , pp. 1115-1144
    • Rosenfeld, E.1    Beauvoit, B.2
  • 59
    • 33749242244 scopus 로고    scopus 로고
    • The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system
    • Shea JM, Kechichian TB, Luberto C, Del Poeta M. 2006. The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system. Infect. Immun. 74:5977-5988.
    • (2006) Infect. Immun. , vol.74 , pp. 5977-5988
    • Shea, J.M.1    Kechichian, T.B.2    Luberto, C.3    Del Poeta, M.4
  • 60
    • 0036008405 scopus 로고    scopus 로고
    • Complementation of a capsule deficient Cryptococcus neoformans with CAP64 restores virulence in a murine lung infection
    • Wilder JA, Olson GK, Chang YC, Kwon-Chung KJ, Lipscomb MF. 2002. Complementation of a capsule deficient Cryptococcus neoformans with CAP64 restores virulence in a murine lung infection. Am. J. Respir. Cell Mol. Biol. 26:306-314.
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.26 , pp. 306-314
    • Wilder, J.A.1    Olson, G.K.2    Chang, Y.C.3    Kwon-Chung, K.J.4    Lipscomb, M.F.5
  • 61
    • 0029886340 scopus 로고    scopus 로고
    • The second capsule gene of Cryptococcus neoformans, CAP64, is essential for virulence
    • Chang YC, Penoyer LA, Kwon-Chung KJ. 1996. The second capsule gene of Cryptococcus neoformans, CAP64, is essential for virulence. Infect. Immun. 64:1977-1983.
    • (1996) Infect. Immun. , vol.64 , pp. 1977-1983
    • Chang, Y.C.1    Penoyer, L.A.2    Kwon-Chung, K.J.3


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