Update information on drug metabolism systems - 2009, Part II. Summary of information on the effects of diseases and environmental factors on human cytochrome P450 (CYP) enzymes and transporters

Current Drug Metabolism

Volumn 11, Issue 1, 2010, Pages 4-84

  Rendic, Slobodan ^a   Guengerich, F Peter ^b  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activity; CYPs; Cytochrome P450s; Demographic factors; Environmental condition; Expression; Illness; Physiological conditions; Transporters

Indexed keywords

ABC TRANSPORTER A1; CAFFEINE; CARRIER PROTEINS AND BINDING PROTEINS; COUMARIN; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A; CYTOCHROME P450 2A6; CYTOCHROME P450 2B; CYTOCHROME P450 2B6; CYTOCHROME P450 2C; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 2J2; CYTOCHROME P450 3A; CYTOCHROME P450 3A4; DOCETAXEL; ERYTHROMYCIN; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; MULTIDRUG RESISTANCE PROTEIN 1; NAVELBINE; THEOPHYLLINE; UMBELLIFERONE; UNINDEXED DRUG;

ALCOHOL LIVER DISEASE; BROCCOLI; CIGARETTE SMOKING; DIETARY INTAKE; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EFFECT; DRUG METABOLISM; DRUG UPTAKE; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KWASHIORKOR; LIVER DISEASE; MALIGNANT NEOPLASTIC DISEASE; OXIDATIVE STRESS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SHEAR STRESS;

BIOTRANSFORMATION; CARRIER PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE; DRUG DESIGN; ENVIRONMENT; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; ISOENZYMES; MALE; METABOLOMICS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PHENOTYPE; POLYMORPHISM, GENETIC; SYSTEMS BIOLOGY; SYSTEMS INTEGRATION;

EID: 77950842489     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920010791110917     Document Type: Review

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