GABA A agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic

Biochemical Pharmacology

Volumn 68, Issue 8, 2004, Pages 1573-1580

  Krogsgaard Larsen, Povl ^a,c   Frølund, Bente ^a   Liljefors, Tommy ^a   Ebert, Bjarke ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

^c 35 HC Andersens Boulevard   (Denmark)

Author keywords

4 PIOL; Agonist; Clinical studies; Functional selectivity; GABA A receptor; Muscimol; Non opioid analgesia; Novel hypnotic effects; Partial agonist; THIP (Gaboxadol)

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; ANALGESIC AGENT; ARECAIDINE; BENZODIAZEPINE; GABOXADOL; HYPNOTIC AGENT; MUSCIMOL;

ANALGESIA; ANXIETY DISORDER; ARTICLE; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; EUPHORIA; HUMAN; NAUSEA; NONHUMAN; PAIN; PRIORITY JOURNAL; SEDATION;

ANALGESICS, NON-NARCOTIC; ANXIETY; GABA AGONISTS; GABA ANTAGONISTS; HUMANS; HYPNOTICS AND SEDATIVES; ISOXAZOLES; PIPERIDINES; RECEPTORS, GABA-A; SLEEP DISORDERS;

EID: 4644268516     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.06.040     Document Type: Article

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