메뉴 건너뛰기




Volumn 36, Issue 4, 2013, Pages 223-237

Antileukemic T-cell responses can be predicted by the composition of specific regulatory T-cell subpopulations

Author keywords

AML; dendritic cells; immune escape; regulatory T cells

Indexed keywords

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; DONOR LYMPHOCYTE INFUSION; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MALE; MONONUCLEAR CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SCHOOL CHILD; STEM CELL TRANSPLANTATION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 84876786701     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/CJI.0b013e31829180e7     Document Type: Article
Times cited : (18)

References (64)
  • 1
    • 0036716596 scopus 로고    scopus 로고
    • New drugs in acute myeloid leukemia
    • Giles FJ. New drugs in acute myeloid leukemia. Curr Oncol Rep. 2002;5:369-374.
    • (2002) Curr Oncol Rep. , vol.5 , pp. 369-374
    • Giles, F.J.1
  • 3
    • 67650889486 scopus 로고    scopus 로고
    • The role of soluble and cell-surface expressed 4-1BB ligand in patients with malignant hemopoietic disorders
    • Scholl N, Loibl J, Kremser A, et al. The role of soluble and cell-surface expressed 4-1BB ligand in patients with malignant hemopoietic disorders. Leuk Lymphoma. 2009;3:427-436.
    • (2009) Leuk Lymphoma. , vol.3 , pp. 427-436
    • Scholl, N.1    Loibl, J.2    Kremser, A.3
  • 4
    • 0033969037 scopus 로고    scopus 로고
    • HLA class I expression on human cancer cells: Implications for effective immunotherapy
    • DOI 10.1016/S0198-8859(99)00150-0, PII S0198885999001500
    • Tait BD. HLA class I expression on human cancer cells. Implications for effective immunotherapy. Hum Immunol. 2000;2:158-165. (Pubitemid 30075238)
    • (2000) Human Immunology , vol.61 , Issue.2 , pp. 158-165
    • Tait, B.D.1
  • 5
    • 77953442400 scopus 로고    scopus 로고
    • Impaired antigen presentation in Neoplasia: Basic mechanisms and implications for acute myeloid leukemia
    • van Luijn MM, van den Ancker W, Chamuleau ME, et al. Impaired antigen presentation in neoplasia: basic mechanisms and implications for acute myeloid leukemia. Immunotherapy. 2010;1:85-97.
    • (2010) Immunotherapy , vol.1 , pp. 85-97
    • Van Luijn, M.M.1    Van Den Ancker, W.2    Chamuleau, M.E.3
  • 10
    • 12144249838 scopus 로고    scopus 로고
    • + T-cells from patients with type 1 diabetes
    • DOI 10.2337/diabetes.54.1.92
    • Lindley S, Dayan CM, Bishop A, et al. Defective suppressor function in CD4+(+)CD25+(+) T-cells from patients with type 1 diabetes. Diabetes. 2005;1:92-99. (Pubitemid 40105099)
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peatman, M.5    Tree, T.I.M.6
  • 11
    • 0033402324 scopus 로고    scopus 로고
    • Extracorporeal photopheresis induces apoptosis in the lymphocytes of cutaneous T-cell lymphoma and graft-versus-host disease patients
    • Bladon J, Taylor PC. Extracorporeal photopheresis induces apoptosis in the lymphocytes of cutaneous T-cell lymphoma and graft-versus-host disease patients. Br J Haematol. 1999; 4:707-711. (Pubitemid 30020139)
    • (1999) British Journal of Haematology , vol.107 , Issue.4 , pp. 707-711
    • Bladon, J.1    Taylor, P.C.2
  • 12
    • 77953633327 scopus 로고    scopus 로고
    • TGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis
    • Zhang H, Podojil JR, Chang J, et al. TGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis. J Immunol. 2010;12:6629-6636.
    • (2010) J Immunol. , vol.12 , pp. 6629-6636
    • Zhang, H.1    Podojil, J.R.2    Chang, J.3
  • 13
    • 44649144463 scopus 로고    scopus 로고
    • + regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells
    • + regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells. J Immunol. 2007;7:4685-4693.
    • (2007) J Immunol. , vol.7 , pp. 4685-4693
    • DiPaolo, R.J.1    Brinster, C.2    Davidson, T.S.3
  • 16
    • 70449723156 scopus 로고    scopus 로고
    • Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia
    • Zhou Q, Bucher C, Munger ME, et al. Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia. Blood. 2009;18:3793-3802.
    • (2009) Blood. , vol.18 , pp. 3793-3802
    • Zhou, Q.1    Bucher, C.2    Munger, M.E.3
  • 17
    • 66149179122 scopus 로고    scopus 로고
    • Increased frequency and suppression by regulatory T cells in patients with acute myelogenous leukemia
    • Szczepanski MJ, Szajnik M, Czystowska M, et al. Increased frequency and suppression by regulatory T cells in patients with acute myelogenous leukemia. Clin Cancer Res. 2009; 10:3325-3332.
    • (2009) Clin Cancer Res. , vol.10 , pp. 3325-3332
    • Szczepanski, M.J.1    Szajnik, M.2    Czystowska, M.3
  • 19
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;3:1151-1164.
    • (1995) J Immunol. , vol.3 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 20
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • DOI 10.1126/science.1079490
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;5609:1057-1061. (Pubitemid 36222930)
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 21
    • 0037385330 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1038/ni904
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. 2003;4:330-336. (Pubitemid 36432314)
    • (2003) Nature Immunology , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 22
    • 70049095101 scopus 로고    scopus 로고
    • How do regulatory T cells work?
    • Corthay A. How do regulatory T cells work? Scand J Immunol. 2009;4:326-336.
    • (2009) Scand J Immunol. , vol.4 , pp. 326-336
    • Corthay, A.1
  • 23
    • 34547774699 scopus 로고    scopus 로고
    • + T cell subsets
    • DOI 10.1189/jlb.1006644
    • Pyzik M, Piccirillo CA. TGF-beta1 modulates Foxp3 expression and regulatory activity in distinct CD4+ T cell subsets. J Leukoc Biol. 2007;2:335-346. (Pubitemid 47230645)
    • (2007) Journal of Leukocyte Biology , vol.82 , Issue.2 , pp. 335-346
    • Pyzik, M.1    Piccirillo, C.A.2
  • 24
    • 0035801335 scopus 로고    scopus 로고
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β
    • DOI 10.1084/jem.194.5.629
    • Nakamura K, Kitani A, Strober W. Cell contact-dependent immunosuppression by CD4+(+)CD25+(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med. 2001;5:629-644. (Pubitemid 32844773)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.5 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 25
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perforin pathway to cause autologous target cell death
    • DOI 10.1016/j.immuni.2004.09.002, PII S1074761304002729
    • Grossman WJ, Verbsky JW, Barchet W, et al. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity. 2004;4:589-601. (Pubitemid 39370513)
    • (2004) Immunity , vol.21 , Issue.4 , pp. 589-601
    • Grossman, W.J.1    Verbsky, J.W.2    Barchet, W.3    Colonna, M.4    Atkinson, J.P.5    Ley, T.J.6
  • 29
    • 79960527416 scopus 로고    scopus 로고
    • Antileukemic T-cell-mediated immune reactions: Limitations and perspectives for future therapies
    • Schmetzer HM. Antileukemic T-cell-mediated immune reactions: limitations and perspectives for future therapies. Immunotherapy. 2011;7:809-811.
    • (2011) Immunotherapy , vol.7 , pp. 809-811
    • Schmetzer, H.M.1
  • 30
    • 77953065918 scopus 로고    scopus 로고
    • The quality and quantity of leukemia-derived dendritic cells from patients with acute myeloid leukemia and myelodysplastic syndrome are a predictive factor for the lytic potential of dendritic cells-primed leukemia-specific T cells
    • Grabrucker C, Liepert A, Dreyig J, et al. The quality and quantity of leukemia-derived dendritic cells from patients with acute myeloid leukemia and myelodysplastic syndrome are a predictive factor for the lytic potential of dendritic cells-primed leukemia-specific T cells. J Immunother. 2010;5: 523-537.
    • (2010) J Immunother. , vol.5 , pp. 523-537
    • Grabrucker, C.1    Liepert, A.2    Dreyig, J.3
  • 31
    • 77956173577 scopus 로고    scopus 로고
    • Quality of T-cells after stimulation with leukemia-derived dendritic cells (DC) from patients with acute myeloid leukemia (AML) or myeloid dysplastic syndrome (MDS) is predictive for their leukemia cytotoxic potential
    • Liepert A, Grabrucker C, Kremser A, et al. Quality of T-cells after stimulation with leukemia-derived dendritic cells (DC) from patients with acute myeloid leukemia (AML) or myeloid dysplastic syndrome (MDS) is predictive for their leukemia cytotoxic potential. Cell Immunol. 2010;1:23-30.
    • (2010) Cell Immunol. , vol.1 , pp. 23-30
    • Liepert, A.1    Grabrucker, C.2    Kremser, A.3
  • 32
    • 77649163905 scopus 로고    scopus 로고
    • Dendritic cells (DCs) can be successfully generated from leukemic blasts in individual patients with AML or MDS: An evaluation of different methods
    • Kremser A, Dressig J, Grabrucker C, et al. Dendritic cells (DCs) can be successfully generated from leukemic blasts in individual patients with AML or MDS: an evaluation of different methods. J Immunother. 2010;2:185-199.
    • (2010) J Immunother. , vol.2 , pp. 185-199
    • Kremser, A.1    Dressig, J.2    Grabrucker, C.3
  • 33
    • 80053035393 scopus 로고    scopus 로고
    • Various "dendritic cell antigens" are already expressed on uncultured blasts in acute myeloid leukemia and myelodysplastic syndromes
    • Dreyssig J, Kremser A, Liepert A, et al. Various "dendritic cell antigens" are already expressed on uncultured blasts in acute myeloid leukemia and myelodysplastic syndromes. Immuno-therapy. 2011;9:1113-1124.
    • (2011) Immuno-therapy , vol.9 , pp. 1113-1124
    • Dreyssig, J.1    Kremser, A.2    Liepert, A.3
  • 34
    • 34249752808 scopus 로고    scopus 로고
    • Quantification of ex vivo generated dendritic cells (DC) and leukemia-derived DC contributes to estimate the quality of DC, to detect optimal DC-generating methods or to optimize DC-mediated T-cell-activation-procedures ex vivo or in vivo [16]
    • DOI 10.1038/sj.leu.2404639, PII 2404639
    • Schmetzer HM, Kremser A, Loibl J, et al. Quantification of ex vivo generated dendritic cells (DC) and leukemia-derived DC contributes to estimate the quality of DC, to detect optimal DC-generating methods or to optimize DC-mediated T-cell-activation-procedures ex vivo or in vivo. Leukemia. 2007;6: 1338-1341. (Pubitemid 46831833)
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1338-1341
    • Schmetzer, H.M.1    Kremser, A.2    Loibl, J.3    Kroell, T.4    Kolb, H.-J.5
  • 35
    • 0037093217 scopus 로고    scopus 로고
    • + immune regulatory cells inhibits graft-versus-host disease lethality
    • DOI 10.1182/blood.V99.10.3493
    • Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4+(+)CD25+(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood. 2002; 10:3493-3499. (Pubitemid 34534513)
    • (2002) Blood , vol.99 , Issue.10 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 36
    • 0141461418 scopus 로고    scopus 로고
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • DOI 10.1038/nm915
    • Edinger M, Hoffmann P, Ermann J, et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med. 2003;9:1144-1150. (Pubitemid 37173698)
    • (2003) Nature Medicine , vol.9 , Issue.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3    Drago, K.4    Garrison Fathman, C.5    Strober, S.6    Negrin, R.S.7
  • 37
    • 0037025943 scopus 로고    scopus 로고
    • + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • DOI 10.1084/jem.20020399
    • Hoffmann P, Ermann J, Edinger M, et al. Donor-type CD4+(+)CD25+(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002;3:389-399. (Pubitemid 34875667)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.3 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Garrison Fathman, C.4    Strober, S.5
  • 38
    • 0242557055 scopus 로고    scopus 로고
    • + T cells to allow an effective graft-versus-leukemia response
    • DOI 10.1053/bbmt.2003.50027, PII S1083879103000636
    • Jones SC, Murphy GF, Korngold R. Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia response. Biol Blood Marrow Transplant. 2003; 4:243-256. (Pubitemid 40045611)
    • (2003) Biology of Blood and Marrow Transplantation , vol.9 , Issue.4 , pp. 243-256
    • Jones, S.C.1    Murphy, G.F.2    Korngold, R.3
  • 39
    • 0346690399 scopus 로고    scopus 로고
    • + regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
    • DOI 10.1172/JCI200317702
    • Trenado A, Charlotte F, Fisson S, et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J Clin Invest. 2003;11:1688-1696. (Pubitemid 38063726)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.11 , pp. 1688-1696
    • Trenado, A.1    Charlotte, F.2    Fisson, S.3    Yagello, M.4    Klatzmann, D.5    Salomon, B.L.6    Cohen, J.L.7
  • 40
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • DOI 10.1182/blood-2006-02-002774
    • Beyer M, Schultze JL. Regulatory T cells in cancer. Blood. 2006;3:804-811. (Pubitemid 44154611)
    • (2006) Blood , vol.108 , Issue.3 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 41
    • 14644387445 scopus 로고    scopus 로고
    • CD69 is an immunoregulatory molecule induced following activation
    • DOI 10.1016/j.it.2004.12.006
    • Sancho D, Gomez M, Sanchez-Madrid F. CD69 is an immunoregulatory molecule induced following activation. Trends Immunol. 2005;3:136-140. (Pubitemid 40312520)
    • (2005) Trends in Immunology , vol.26 , Issue.3 , pp. 136-140
    • Sancho, D.1    Gomez, M.2    Sanchez-Madrid, F.3
  • 44
    • 0026528868 scopus 로고
    • Activation induced changes in expression and structure of the IL-7 receptor on human T cells
    • Foxwell BM, Taylor-Fishwick DA, Simon JL, et al. Activation induced changes in expression and structure of the IL-7 receptor on human T cells. Int Immunol. 1992;2:277-282.
    • (1992) Int Immunol. , vol.2 , pp. 277-282
    • Foxwell, B.M.1    Taylor-Fishwick, D.A.2    Simon, J.L.3
  • 45
    • 77954141914 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells in the human immune system
    • Sakaguchi S, Miyara M, Costantino CM, et al. FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol. 2010;7:490-500.
    • (2010) Nat Rev Immunol. , vol.7 , pp. 490-500
    • Sakaguchi, S.1    Miyara, M.2    Costantino, C.M.3
  • 46
    • 66949171924 scopus 로고    scopus 로고
    • Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
    • Miyara M, Yoshioka Y, Kitoh A, et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity. 2009;6: 899-911.
    • (2009) Immunity , vol.6 , pp. 899-911
    • Miyara, M.1    Yoshioka, Y.2    Kitoh, A.3
  • 49
    • 33846283803 scopus 로고    scopus 로고
    • Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells
    • DOI 10.1016/j.jim.2006.10.008, PII S0022175906002997
    • Hartigan-O'Connor DJ, Poon C, Sinclair E, et al. Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells. J Immunol Methods. 2007;1-2:41-52. (Pubitemid 46110995)
    • (2007) Journal of Immunological Methods , vol.319 , Issue.1-2 , pp. 41-52
    • Hartigan-O'Connor, D.J.1    Poon, C.2    Sinclair, E.3    McCune, J.M.4
  • 50
    • 28044434385 scopus 로고    scopus 로고
    • high regulatory T cells with their higher apoptotic and proliferating status in peripheral blood of acute myeloid leukemia patients
    • DOI 10.1111/j.1600-0609.2005.00537.x
    • Wang X, Zheng J, Liu J, et al. Increased population of CD4+(+)CD25(high), regulatory T cells with their higher apoptotic and proliferating status in peripheral blood of acute myeloid leukemia patients. Eur J Haematol. 2005;6:468-476. (Pubitemid 41687780)
    • (2005) European Journal of Haematology , vol.75 , Issue.6 , pp. 468-476
    • Wang, X.1    Zheng, J.2    Liu, J.3    Yao, J.4    He, Y.5    Li, X.6    Yu, J.7    Yang, J.8    Liu, Z.9    Huang, S.10
  • 51
    • 79960898228 scopus 로고    scopus 로고
    • Elevated frequencies of CD4 CD25 CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia
    • Shenghui Z, Yixiang H, Jianbo W, et al. Elevated frequencies of CD4 CD25 CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia. Int J Cancer. 2010;6:1373-1381.
    • (2010) Int J Cancer , vol.6 , pp. 1373-1381
    • Shenghui, Z.1    Yixiang, H.2    Jianbo, W.3
  • 52
    • 45549107134 scopus 로고    scopus 로고
    • Revival of CD8+ treg-mediated suppression
    • Smith TR, Kumar V. Revival of CD8+ Treg-mediated suppression. Trends Immunol. 2008;7:337-342.
    • (2008) Trends Immunol. , vol.7 , pp. 337-342
    • Smith, T.R.1    Kumar, V.2
  • 53
    • 57649101649 scopus 로고    scopus 로고
    • CD8+ regulatory T cells, their suppressive mechanisms, and regulation in cancer
    • Wang RF. CD8+ regulatory T cells, their suppressive mechanisms, and regulation in cancer. Hum Immunol. 2008; 11:811-814.
    • (2008) Hum Immunol. , vol.11 , pp. 811-814
    • Wang, R.F.1
  • 56
    • 63849224217 scopus 로고    scopus 로고
    • Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue
    • Chaput N, Louafi S, Bardier A, et al. Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue. Gut. 2009;4:520-529.
    • (2009) Gut. , vol.4 , pp. 520-529
    • Chaput, N.1    Louafi, S.2    Bardier, A.3
  • 58
    • 33645510596 scopus 로고    scopus 로고
    • Persistence of naive CD45RA+ regulatory T cells in adult life
    • Seddiki N, Santner-Nanan B, Tangye SG, et al. Persistence of naive CD45RA+ regulatory T cells in adult life. Blood. 2006;7:2830-2838.
    • (2006) Blood. , vol.7 , pp. 2830-2838
    • Seddiki, N.1    Santner-Nanan, B.2    Tangye, S.G.3
  • 60
    • 51049101334 scopus 로고    scopus 로고
    • Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
    • Hasko G, Linden J, Cronstein B, et al. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov. 2008;9:759-770.
    • (2008) Nat Rev Drug Discov. , vol.9 , pp. 759-770
    • Hasko, G.1    Linden, J.2    Cronstein, B.3
  • 61
    • 65649133976 scopus 로고    scopus 로고
    • Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: Immunopathogenesis and therapeutic implications
    • Andre S, Tough DF, Lacroix-Desmazes S, et al. Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications. Am J Pathol. 2009;5:1575-1587.
    • (2009) Am J Pathol. , vol.5 , pp. 1575-1587
    • Andre, S.1    Tough, D.F.2    Lacroix-Desmazes, S.3
  • 63
    • 33746328653 scopus 로고    scopus 로고
    • + regulatory T cells including suppressors of alloreactivity
    • DOI 10.1111/j.0105-2896.2006.00422.x
    • Yamazaki S, Inaba K, Tarbell KV, et al. Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. Immunol Rev. 2006;314-329. (Pubitemid 44116717)
    • (2006) Immunological Reviews , vol.212 , pp. 314-329
    • Yamazaki, S.1    Inaba, K.2    Tarbell, K.V.3    Steinman, R.M.4
  • 64
    • 43649096023 scopus 로고    scopus 로고
    • Generation of highly suppressive adaptive CD8+(+)CD25+(+)FOXP3+(+) regulatory T cells by continuous antigen stimulation
    • Mahic M, Henjum K, Yaqub S, et al. Generation of highly suppressive adaptive CD8+(+)CD25+(+)FOXP3+(+) regulatory T cells by continuous antigen stimulation. Eur J Immunol. 2008;3:640-646.
    • (2008) Eur J Immunol. , vol.3 , pp. 640-646
    • Mahic, M.1    Henjum, K.2    Yaqub, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.