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Volumn 33, Issue 2, 2010, Pages 185-199

Dendritic cells (DCs) can be successfully generated from leukemic blasts in individual patients with AML or MDS: An evaluation of different methods

Author keywords

Acute myeloid leukaemia; Dendritic cells; Immunotherapy; Myelodysplastic syndromes; Serum free culture

Indexed keywords

CALCIUM IONOPHORE; CYTOKINE; PICIBANIL; POLYINOSINIC POLYCYTIDYLIC ACID;

EID: 77649163905     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e3181b8f4ce     Document Type: Article
Times cited : (59)

References (53)
  • 2
    • 0035101804 scopus 로고    scopus 로고
    • Leukemic dendritic cells generated in the presence of FLT3 ligand have the capacity to stimulate an autologous leukemia-specific cytotoxic T cell response from patients with acute myeloid leukemia
    • Woiciechowsky A, Regn S, Kolb HJ, et al. Leukemic dendritic cells generated in the presence of FLT3 ligand have the capacity to stimulate an autologous leukemia-specific cytotoxic T cell response from patients with acute myeloid leukemia. Leukemia. 2001;15:246-255.
    • (2001) Leukemia , vol.15 , pp. 246-255
    • Woiciechowsky, A.1    Regn, S.2    Kolb, H.J.3
  • 3
    • 0030897009 scopus 로고    scopus 로고
    • International scoring system for evaluating prognosis in myelodysplastic syndromes
    • Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;89:2079-2088.
    • (1997) Blood , vol.89 , pp. 2079-2088
    • Greenberg, P.1    Cox, C.2    Lebeau, M.M.3
  • 4
    • 0038556841 scopus 로고    scopus 로고
    • New approaches in the immunotherapy of haematological malignancies
    • Costello RT, Rey J, Fauriat C, et al. New approaches in the immunotherapy of haematological malignancies. Eur J Hae-matol. 2003;70:333-345.
    • (2003) Eur J Hae-matol , vol.70 , pp. 333-345
    • Costello, R.T.1    Rey, J.2    Fauriat, C.3
  • 5
    • 84925548986 scopus 로고    scopus 로고
    • The instructive role of dendritic cells on T-cell responses
    • Sallusto F, Lanzavecchia A. The instructive role of dendritic cells on T-cell responses. Arthritis Res. 2002;4(suppl 3): S127-S132.
    • (2002) Arthritis Res , vol.4 , Issue.SUPPL. 3
    • Sallusto, F.1    Lanzavecchia, A.2
  • 6
    • 0037137573 scopus 로고    scopus 로고
    • A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: Implications for immunotherapy
    • Lee AW, Truong T, Bickham K, et al. A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: implications for immunotherapy. Vaccine. 2002;20(suppl 4):A8-A22.
    • (2002) Vaccine , vol.20 , Issue.SUPPL. 4
    • Lee, A.W.1    Truong, T.2    Bickham, K.3
  • 7
    • 0037268105 scopus 로고    scopus 로고
    • Rapid generation of antigen-presenting cells from leukaemic blasts in acute myeloid leukaemia
    • Westers TM, Stam AG, Scheper RJ, et al. Rapid generation of antigen-presenting cells from leukaemic blasts in acute myeloid leukaemia. Cancer Immunol Immunother. 2003;52:17-27.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 17-27
    • Westers, T.M.1    Stam, A.G.2    Scheper, R.J.3
  • 8
    • 0037561000 scopus 로고    scopus 로고
    • Serum-free generation of antigen presenting cells from acute myeloid leukaemic blasts for active specific immunisation
    • Houtenbos I, Westers TM, Stam AG, et al. Serum-free generation of antigen presenting cells from acute myeloid leukaemic blasts for active specific immunisation. Cancer Immunol Immunother. 2003;52:455-462.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 455-462
    • Houtenbos, I.1    Westers, T.M.2    Stam, A.G.3
  • 9
    • 2442509079 scopus 로고    scopus 로고
    • Poly (I:C) used for human dendritic cell maturation preserves their ability to secondarily secrete bioactive IL-12
    • Rouas R, Lewalle P, El Ouriaghli F, et al. Poly (I:C) used for human dendritic cell maturation preserves their ability to secondarily secrete bioactive IL-12. Int Immunol. 2004;16: 767-773.
    • (2004) Int Immunol , vol.16 , pp. 767-773
    • Rouas, R.1    Lewalle, P.2    El Ouriaghli, F.3
  • 10
    • 0346399560 scopus 로고    scopus 로고
    • Generation of mature dendritic cells fully capable of T helper type 1 polarization using OK-432 combined with prostaglandin e (2)
    • Sato M, Takayama T, Tanaka H, et al. Generation of mature dendritic cells fully capable of T helper type 1 polarization using OK-432 combined with prostaglandin E (2). Cancer Sci. 2003;94:1091-1098.
    • (2003) Cancer Sci , vol.94 , pp. 1091-1098
    • Sato, M.1    Takayama, T.2    Tanaka, H.3
  • 11
    • 23944435482 scopus 로고    scopus 로고
    • Serum-free generation and quantification of functionally active Leukemia-derived DC is possible from malignant blasts in acute myeloid leukemia and myelodysplastic syndromes
    • Kufner S, Fleischer RP, Kroell T, et al. Serum-free generation and quantification of functionally active Leukemia-derived DC is possible from malignant blasts in acute myeloid leukemia and myelodysplastic syndromes. Cancer Immunol Immunother. 2005;54:953-970.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 953-970
    • Kufner, S.1    Fleischer, R.P.2    Kroell, T.3
  • 12
    • 0033936181 scopus 로고    scopus 로고
    • Presence of IgE antibodies to bovine serum albumin in a patient developing anaphylaxis after vaccination with human pep-tide-pulsed dendritic cells
    • Mackensen A, Drager R, Schlesier M, et al. Presence of IgE antibodies to bovine serum albumin in a patient developing anaphylaxis after vaccination with human pep-tide-pulsed dendritic cells. Cancer Immunol Immunother. 2000; 49:152-156.
    • (2000) Cancer Immunol Immunother , vol.49 , pp. 152-156
    • MacKensen, A.1    Drager, R.2    Schlesier, M.3
  • 13
    • 85009914876 scopus 로고    scopus 로고
    • Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1
    • Roddie PH, Horton Y, Turner ML. Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. Leukemia. 2002;16:84-93.
    • (2002) Leukemia , vol.16 , pp. 84-93
    • Roddie, P.H.1    Horton, Y.2    Turner, M.L.3
  • 14
    • 34249752808 scopus 로고    scopus 로고
    • Quantification of ex vivo generated dendritic cells (DC) and leukemia-derived DC contributes to estimate the quality of DC, to detect optimal DC-generating methods or to optimize DC-mediated T-cell-activation-procedures ex vivo or in vivo
    • Schmetzer HM, Kremser A, Loibl J, et al. Quantification of ex vivo generated dendritic cells (DC) and leukemia-derived DC contributes to estimate the quality of DC, to detect optimal DC-generating methods or to optimize DC-mediated T-cell-activation-procedures ex vivo or in vivo. Leukemia. 2007;21: 1338-1341.
    • (2007) Leukemia , vol.21 , pp. 1338-1341
    • Schmetzer, H.M.1    Kremser, A.2    Loibl, J.3
  • 15
    • 29244431621 scopus 로고    scopus 로고
    • The myelodysplastic syndromes: Diagnosis, molecular biology and risk assessment
    • Bennett JM, Komrokji RS. The myelodysplastic syndromes: diagnosis, molecular biology and risk assessment. Hematology. 2005;10(suppl 1):258-269.
    • (2005) Hematology , vol.10 , Issue.SUPPL. 1 , pp. 258-269
    • Bennett, J.M.1    Komrokji, R.S.2
  • 16
    • 0023766241 scopus 로고
    • Classification of acute leukaemias
    • Hayhoe FG. Classification of acute leukaemias. Blood Rev. 1988;2:186-193.
    • (1988) Blood Rev , vol.2 , pp. 186-193
    • Hayhoe, F.G.1
  • 17
    • 0036717446 scopus 로고    scopus 로고
    • Cytogenetics in acute myeloid leukemia
    • Schoch C, Haferlach T. Cytogenetics in acute myeloid leukemia. Curr Oncol Rep. 2002;4:390-397.
    • (2002) Curr Oncol Rep , vol.4 , pp. 390-397
    • Schoch, C.1    Haferlach, T.2
  • 18
    • 0029866409 scopus 로고    scopus 로고
    • The use of 7-amino actinomycin D in identifying apoptosis: Simplicity of use and broad spectrum of application compared with other techniques
    • Philpott NJ, Turner AJ, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood. 1996;87:2244-2251.
    • (1996) Blood , vol.87 , pp. 2244-2251
    • Philpott, N.J.1    Turner, A.J.2    Scopes, J.3
  • 19
    • 0030603986 scopus 로고    scopus 로고
    • Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood
    • DOI 10.1016/0022-1759(96)00079-8
    • Bender A, Sapp M, Schuler G, et al. Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. J Immunol Methods. 1996;196:121-135. (Pubitemid 26306734)
    • (1996) Journal of Immunological Methods , vol.196 , Issue.2 , pp. 121-135
    • Bender, A.1    Sapp, M.2    Schuler, G.3    Steinman, R.M.4    Bhardwaj, N.5
  • 20
    • 33645995745 scopus 로고    scopus 로고
    • The multiple personalities of the chemokine receptor CCR7 in dendritic cells
    • Sanchez-Sanchez N, Riol-Blanco L, Rodriguez-Fernandez JL. The multiple personalities of the chemokine receptor CCR7 in dendritic cells. J Immunol. 2006;176:5153-5159.
    • (2006) J Immunol , vol.176 , pp. 5153-5159
    • Sanchez-Sanchez, N.1    Riol-Blanco, L.2    Rodriguez-Fernandez, J.L.3
  • 21
    • 0037105972 scopus 로고    scopus 로고
    • The fluorolysis assay, a highly sensitive method for measuring the cytolytic activity of T cells at very low numbers
    • Kienzle N, Olver S, Buttigieg K, et al. The fluorolysis assay, a highly sensitive method for measuring the cytolytic activity of T cells at very low numbers. J Immunol Methods. 2002;267: 99-108.
    • (2002) J Immunol Methods , vol.267 , pp. 99-108
    • Kienzle, N.1    Olver, S.2    Buttigieg, K.3
  • 22
    • 33751267902 scopus 로고    scopus 로고
    • Acute myeloid leukaemia
    • Estey E, Dohner H. Acute myeloid leukaemia. Lancet. 2006;368:1894-1907.
    • (2006) Lancet , vol.368 , pp. 1894-1907
    • Estey, E.1    Dohner, H.2
  • 25
    • 2942627704 scopus 로고    scopus 로고
    • Inhibition of acute myeloid leukemia cell growth by mono-specific and bi-specific anti-CD33 x anti-CD64 antibodies
    • Balaian L, Ball ED. Inhibition of acute myeloid leukemia cell growth by mono-specific and bi-specific anti-CD33 x anti-CD64 antibodies. Leuk Res. 2004;28:821-829
    • (2004) Leuk Res , vol.28 , pp. 821-829
    • Balaian, L.1    Ball, E.D.2
  • 26
    • 33751227854 scopus 로고    scopus 로고
    • Cytotoxic activity of gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia correlates with the expression of protein kinase Syk
    • Balaian L, Ball ED. Cytotoxic activity of gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia correlates with the expression of protein kinase Syk. Leukemia. 2006;20: 2093-2101.
    • (2006) Leukemia , vol.20 , pp. 2093-2101
    • Balaian, L.1    Ball, E.D.2
  • 27
    • 34249817898 scopus 로고    scopus 로고
    • WT1 peptide cancer vaccine for patients with hematopoietic malignancies and solid cancers
    • Oka Y, Tsuboi A, Elisseeva OA, et al. WT1 peptide cancer vaccine for patients with hematopoietic malignancies and solid cancers. Scientific World Journal. 2007;7:649-665.
    • (2007) Scientific World Journal , vol.7 , pp. 649-665
    • Oka, Y.1    Tsuboi, A.2    Elisseeva, O.A.3
  • 28
    • 0037615112 scopus 로고    scopus 로고
    • Monoclonal antibody drug immunoconjugates for targeted treatment of cancer
    • Trail PA, King HD, Dubowchik GM. Monoclonal antibody drug immunoconjugates for targeted treatment of cancer. Cancer Immunol Immunother. 2003;52:328-337.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 328-337
    • Trail, P.A.1    King, H.D.2    Dubowchik, G.M.3
  • 29
    • 0035725104 scopus 로고    scopus 로고
    • Expression of co-stimulatory and adhesion molecules and chemokine or apoptosis receptors on acute myeloid leukaemia: High CD40 and CD11a expression correlates with poor prognosis
    • Brouwer RE, Hoefnagel J, Borger van Der BB et al. Expression of co-stimulatory and adhesion molecules and chemokine or apoptosis receptors on acute myeloid leukaemia: high CD40 and CD11a expression correlates with poor prognosis. Br J Haematol. 2001;115:298-308.
    • (2001) Br J Haematol , vol.115 , pp. 298-308
    • Brouwer, R.E.1    Hoefnagel, J.2    Van Der, B.3
  • 30
    • 0036738149 scopus 로고    scopus 로고
    • Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins
    • Konopleva M, Konoplev S, Hu W, et al. Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins. Leukemia. 2002;16:1713-1724.
    • (2002) Leukemia , vol.16 , pp. 1713-1724
    • Konopleva, M.1    Konoplev, S.2    Hu, W.3
  • 31
    • 0037356948 scopus 로고    scopus 로고
    • Expression of human leucocyte antigens and co-stimulatory molecules on blasts of patients with acute myeloid leukaemia
    • Vollmer M, Li L, Schmitt A, et al. Expression of human leucocyte antigens and co-stimulatory molecules on blasts of patients with acute myeloid leukaemia. Br J Haematol. 2003; 120:1000-1008.
    • (2003) Br J Haematol , vol.120 , pp. 1000-1008
    • Vollmer, M.1    Li, L.2    Schmitt, A.3
  • 32
    • 0029100438 scopus 로고
    • Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients
    • Kolb HJ, Schattenberg A, Goldman JM, et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood. 1995;86:2041-2050.
    • (1995) Blood , vol.86 , pp. 2041-2050
    • Kolb, H.J.1    Schattenberg, A.2    Goldman, J.M.3
  • 33
    • 0242268023 scopus 로고    scopus 로고
    • Adoptive immunotherapy in chimeras with donor lymphocytes
    • Kolb HJ, Schmid C, Chen X, et al. Adoptive immunotherapy in chimeras with donor lymphocytes. Acta Haematol. 2003;110: 110-120.
    • (2003) Acta Haematol , vol.110 , pp. 110-120
    • Kolb, H.J.1    Schmid, C.2    Chen, X.3
  • 34
    • 33746607667 scopus 로고    scopus 로고
    • Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation
    • Schmid C, Schleuning M, Schwerdtfeger R, et al. Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation. Blood. 2006;108: 1092-1099.
    • (2006) Blood , vol.108 , pp. 1092-1099
    • Schmid, C.1    Schleuning, M.2    Schwerdtfeger, R.3
  • 36
    • 0032950187 scopus 로고    scopus 로고
    • Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous, antileukemic T-cell responses
    • Choudhury BA, Liang JC, Thomas EK, et al. Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous, antileukemic T-cell responses. Blood. 1999;93:780-786.
    • (1999) Blood , vol.93 , pp. 780-786
    • Choudhury, B.A.1    Liang, J.C.2    Thomas, E.K.3
  • 37
    • 34248204110 scopus 로고    scopus 로고
    • DC-based cancer vaccines
    • Gilboa E. DC-based cancer vaccines. J Clin Invest. 2007;117: 1195-1203.
    • (2007) J Clin Invest , vol.117 , pp. 1195-1203
    • Gilboa, E.1
  • 38
    • 33746034563 scopus 로고    scopus 로고
    • RNA loading of leukemic antigens into cord blood-derived dendritic cells for immuno-therapy
    • Hsu AK, Kerr BM, Jones KL, et al. RNA loading of leukemic antigens into cord blood-derived dendritic cells for immuno-therapy. Biol Blood Marrow Transplant. 2006;12:855-867.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 855-867
    • Hsu, A.K.1    Kerr, B.M.2    Jones, K.L.3
  • 40
    • 0033844404 scopus 로고    scopus 로고
    • Calcium ionophore activation of chronic myelogenous leukemia progenitor cells into dendritic cells is mediated by calcineurin phosphatase
    • Engels FH, Kreisel D, Faries MB, et al. Calcium ionophore activation of chronic myelogenous leukemia progenitor cells into dendritic cells is mediated by calcineurin phosphatase. Leuk Res. 2000;24:795-804.
    • (2000) Leuk Res , vol.24 , pp. 795-804
    • Engels, F.H.1    Kreisel, D.2    Faries, M.B.3
  • 41
    • 33645718864 scopus 로고    scopus 로고
    • In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycy-tidylic acid induces interferon-alpha in human plasmacytoid dendritic cells
    • Loseke S, Grage-Griebenow E, Heine H, et al. In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycy-tidylic acid induces interferon-alpha in human plasmacytoid dendritic cells. Scand J Immunol. 2006;63:264-274.
    • (2006) Scand J Immunol , vol.63 , pp. 264-274
    • Loseke, S.1    Grage-Griebenow, E.2    Heine, H.3
  • 42
    • 21244433908 scopus 로고    scopus 로고
    • Dendritic cells generated from acute myeloid leukemia (AML) blasts maintain the expression of immunogenic leukemia associated antigens
    • Li L, Reinhardt P, Schmitt A, et al. Dendritic cells generated from acute myeloid leukemia (AML) blasts maintain the expression of immunogenic leukemia associated antigens. Cancer Immunol Immunother. 2005;54:685-693.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 685-693
    • Li, L.1    Reinhardt, P.2    Schmitt, A.3
  • 43
    • 33645082656 scopus 로고    scopus 로고
    • Phase I/II study of vaccination with dendritic-like leukaemia cells for the im-munotherapy of acute myeloid leukaemia
    • Roddie H, Klammer M, Thomas C, et al. Phase I/II study of vaccination with dendritic-like leukaemia cells for the im-munotherapy of acute myeloid leukaemia. Br J Haematol. 2006;133:152-157.
    • (2006) Br J Haematol , vol.133 , pp. 152-157
    • Roddie, H.1    Klammer, M.2    Thomas, C.3
  • 44
    • 0034041375 scopus 로고    scopus 로고
    • The generation of dendritic-like cells with increased allostimulatory function from acute myeloid leukemia cells of various FAB subclasses
    • Brouwer RE, van der HM, Kluin-Nelemans HC, et al. The generation of dendritic-like cells with increased allostimulatory function from acute myeloid leukemia cells of various FAB subclasses. Hum Immunol. 2000;61:565-574.
    • (2000) Hum Immunol , vol.61 , pp. 565-574
    • Brouwer, R.E.1    Van Der, H.2    Kluin-Nelemans, H.C.3
  • 45
    • 23244437976 scopus 로고    scopus 로고
    • High expression of costimulatory molecules correlates with low relapse-free survival probability in acute myeloid leukemia (AML)
    • Graf M, Reif S, Hecht K, et al. High expression of costimulatory molecules correlates with low relapse-free survival probability in acute myeloid leukemia (AML). Ann Hematol. 2005;84:287-297.
    • (2005) Ann Hematol , vol.84 , pp. 287-297
    • Graf, M.1    Reif, S.2    Hecht, K.3
  • 47
    • 33746098952 scopus 로고    scopus 로고
    • Flt-3 internal tandem duplication hampers differentiation of AML blasts towards leukemic dendritic cells
    • Houtenbos I, Westers TM, Hess CJ, et al. Flt-3 internal tandem duplication hampers differentiation of AML blasts towards leukemic dendritic cells. Leukemia. 2006;20: 1892-1895.
    • (2006) Leukemia , vol.20 , pp. 1892-1895
    • Houtenbos, I.1    Westers, T.M.2    Hess, C.J.3
  • 48
    • 21744443113 scopus 로고    scopus 로고
    • Leukemia-derived dendritic cells in acute myeloid leukemia exhibit potent migratory capacity
    • Westers TM, Houtenbos I, Snoijs NC, et al. Leukemia-derived dendritic cells in acute myeloid leukemia exhibit potent migratory capacity. Leukemia. 2005;19:1270-1272.
    • (2005) Leukemia , vol.19 , pp. 1270-1272
    • Westers, T.M.1    Houtenbos, I.2    Snoijs, N.C.3
  • 49
    • 0031712324 scopus 로고    scopus 로고
    • Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
    • Sallusto F, Schaerli P, Loetscher P, et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur J Immunol. 1998;28:2760-2769.
    • (1998) Eur J Immunol , vol.28 , pp. 2760-2769
    • Sallusto, F.1    Schaerli, P.2    Loetscher, P.3
  • 51
    • 22644439034 scopus 로고    scopus 로고
    • Employing the immunological synapse in AML: Development of leukemic dendritic cells for active specific immunization
    • Houtenbos I, Westers TM, Ossenkoppele GJ, et al. Employing the immunological synapse in AML: development of leukemic dendritic cells for active specific immunization. Immunobiology. 2005;210:249-257.
    • (2005) Immunobiology , vol.210 , pp. 249-257
    • Houtenbos, I.1    Westers, T.M.2    Ossenkoppele, G.J.3
  • 52
    • 33645451900 scopus 로고    scopus 로고
    • Leukemia-derived dendritic cells: Towards clinical vaccination protocols in acute myeloid leukemia
    • Houtenbos I, Westers TM, Ossenkoppele GJ, et al. Leukemia-derived dendritic cells: towards clinical vaccination protocols in acute myeloid leukemia. Haematologica. 2006;91: 348-355.
    • (2006) Haematologica , vol.91 , pp. 348-355
    • Houtenbos, I.1    Westers, T.M.2    Ossenkoppele, G.J.3
  • 53
    • 33746074415 scopus 로고    scopus 로고
    • Leukaemic dendritic cell vaccination for patients with acute myeloid leukaemia [1]
    • DOI 10.1111/j.1365-2141.2006.06196.x
    • Houtenbos I, Westers TM, Ossenkoppele GJ, et al. Leukaemic dendritic cell vaccination for patients with acute myeloid leukaemia. Br J Haematol. 2006;134:445-446. (Pubitemid 44079559)
    • (2006) British Journal of Haematology , vol.134 , Issue.4 , pp. 445-446
    • Houtenbos, I.1    Westers, T.M.2    Ossenkoppele, G.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.