Amelioration of cyclophosphamide-induced hepatotoxicity by the root extract of Decalepis hamiltonii in mice

Food and Chemical Toxicology

Volumn 57, Issue , 2013, Pages 179-184

  Zarei, Mahsa ^a   Shivanandappa, T ^a  

^a UNIVERSITY OF MYSORE   (India)

Author keywords

Antioxidant enzymes; Cyclophosphamide; Decalepis hamiltonii; Hepatotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; CYCLOPHOSPHAMIDE; DECALEPIS HAMILTONII EXTRACT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOCYNACEAE; ARTICLE; CONTROLLED STUDY; DECALEPIS HAMILTONII; DOWN REGULATION; DRUG SAFETY; ENZYME ASSAY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PLANT ROOT; TOXIC HEPATITIS;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; APOCYNACEAE; ASPARTATE AMINOTRANSFERASES; CATALASE; CYCLOPHOSPHAMIDE; ENZYMES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LIPID PEROXIDATION; LIVER; MICE; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT ROOTS; PROTECTIVE AGENTS; SUPEROXIDE DISMUTASE;

DECALEPIS HAMILTONII; MUS;

EID: 84876699989     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.03.028     Document Type: Article

References (56)

1. Aebi, H., 1983. Methods of enzymatic analysis, Verlag Chenie, Weinheim, vol. 2, pp. 674-678.
2. Aguilar-Mahecha A., Hales B.F., Robaire B. Chronic cyclophosphamide treatment alters the expression of stress response genes in rat male germ cells. Biol. Reprod. 2002, 66:1024-1032.
3. Anderstam B., Vaca C., Ringdahl M.H. Lipid peroxide level in a murine adenocarcinoma exposed to hyperthermia: the role of glutathione depletion. Radiat. Res. 1992, 132:296-300.
4. Ansari R.A., Tripathi S.C., Patnaik G.K., Dhawan B.N. Antihepatotoxic properties of picroliv: an active fraction from rhizomes of Picrorhiza kurroa. J. Ethnopharmacol. 1991, 34:61-68.
5. Bacon A.M., Rosenberg S.A. Cyclophosphamide hepatotoxicity in a patient with systemic lupus erythematosus. Ann. Int. Med. 1982, 97:62-63.
6. Bhatia K., Kaur M., Atif F., Ali M., Rehman H., Rahman S., Raisuddin S. Aqueous extract of Trigonella foenum-graecum L. ameliorates additive urotoxicity of buthionine sulfoximine and cyclophosphamide in mice. Food Chem. Toxicol. 2006, 44:1744-1750.
7. Bhatia K., Ahmad F., Rashid H., Raisuddin S. Protective effect of S-allylcysteine against cyclophosphamide-induced bladder hemorrhagic cystitis in mice. Food Chem. Toxicol. 2008, 46:3368-3374.
8. Calberg, I., Mannervik, B., 1985. Glutathione reductase. In: Meister, A. (Ed.). Method Enzymol., p. 113, pp. 484-490.
9. Cathcart S., Schwiers E., Ames B.N. Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal. Biochem. 1983, 134:111-116.
10. Dollery, C., 1999. Cyclophosphamide. In: Dollery, C., (Ed.), Therapeutic drugs. Edinburg' Churchill Livingstone, pp. 349-353.
11. Ellman G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 1959, 82:70-77.
12. Goldberg M.A., Antin J.H., Guinan E.C., Rappeport J.M. Cyclophosphamide cardiotoxicity: an analysis of doing as a risk factor. Blood 1986, 68:1114-1118.
13. Hamilton M.G., Dorandeu F.M., McCaffery M., Lundy M., Sawyer T.W. Modification of cytosolicfree calcium concentration in human keratinocytes after sulfur mustard exposure. Toxicol. In Vitro 1998, 12:365-372.
14. Haque R., Bin-Hafeez B., Ahmad I., Parvez S., Pandey S., Raisuddin S. Protective effects ofEmblica officinalisGaertn. in cyclophosphamide-treated mice. Hum. Exp. Toxicol. 2001, 20:643-650.
15. Haque R., Bin-Hafeez B., Parvez S., Pandey S., Sayeed I., Ali M., Raisuddin S. Aqueous extract of walnut (Juglans regiaL.) protects mice against cyclophosphamide induced biochemical toxicity. Hum. Exp. Toxicol. 2003, 22:473-480.
16. Harish R., Divakar S., Srivastava A., Shivanandappa T. Isolation of antioxidant compounds from the methanolic extract of the roots of Decalepis hamiltonii (Wight and Arn.). J. Agric. Food Chem. 2005, 53:7709-7714.
17. Hayes J.D., Flanagan J.U., Jowsey I.R. Glutathione transferases. Ann. Rev. Pharmacol. Toxicol. 2005, 45:51-88.
18. Jalali A.S., Hasanzadeh S., Malekinejad H. Achillea millefolium inflorescence aqueous extract ameliorates cyclophosphamide-induced toxicity in rat testis: stereological evidences. Chin J. Nat. Med. 2012, 10:247-254.
19. Kern J.C., Kehrer J.P. Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis. Chem. Biol. Interact. 2002, 139:79-95.
20. Kornberg A. Lactic dehydrogenase of muscle. Methods Enzymol. 1955, 1:441-443.
21. Kouidhi S., Rouissi K., Hamrita B., Ouerhani S., Cherif M., Benammar A.E. Therapeutic effects of aloe Vera plant extract against cyclophosphamide and buthionine sulfoximine induced toxicities in the bladder. Biochem. Pharmacol. 2012, 1:1.
22. Kumar K.B.H., Kuttan R. Chemoprotective activity of an extract ofPhyllanthus amarusagainst cyclophosphamide induced toxicity in mice. Phytomedicine 2005, 12:494-500.
23. Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein measurement with Folin-Phenol reagent. J. Biol. Chem. 1951, 193:265-275.
24. Ludeman S.M. The chemistry of the metabolites of cyclophosphamide. Curr. Pharm. Des. 1999, 5:627-643.
25. Manda K., Bhatia A.L. Prophylactic action of melatonin against cyclophosphamide-induced oxidative stress in mice. Cell Biol. Toxicol. 2003, 19:367-372.
26. Mannervik, B., 1985. Glutathione peroxidase. In: A. Miester (Ed.). Methods Enzymol., vol. 113, pp. 490-495.
27. Marklund S., Marklund G. Involvement of the superoxide anion in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Euro. J. Biochem. 1974, 47:469-474.
28. Meister A., Andersen M.E. Glutathione. Ann. Rev. Biochem. 1983, 52:711-760.
29. Nayar R.C., Shetty J.K.P., Mary Z., Yoganarshimhan S.N. Pharmacognostical studies on the root of Decalepis hamiltonii Wt. and Arn. and comparison with Hemidesmus indicus (L.) R. Br. Proc. f Indian Acad Sci. 1978, 87:37-48.
30. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95:351-358.
31. Okado-Matsumoto A., Fridovich I. Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu, Zn-SOD in mitochondria. J. Biol. Chem. 2001, 19:38388-38393.
32. Perini P., Calabrese M., Rinaldi L., Gallo P. The safety profile of cyclophosphamide in multiple sclerosis therapy. Expert Opin. Drug Safety 2007, 6:183-190.
33. Pratheeshkumar P., Kuttan G. Cardiospermum halicacabum inhibits cyclophosphamide induced immunosupression and oxidative stress in mice and also regulates iNOS and COX-2 gene expression in LPS stimulated macrophages. Asian Pac. J. Cancer Prev. 2010, 11:1245-1252.
34. Rajasekaran N.S., Devaraj H., Devaraj S.N. The effect of glutathione monoester (GME) on glutathione (GSH) depleted rat liver. J. Nutr. Biochem. 2002, 13:302-306.
35. Selvakumar E., Prahalathan C., Mythili Y., Varalakshmi P. Mitigation of oxidative stress in cyclophosphamide-challenged hepatic tissue by DL-alpha-lipoic acid. Mol. Cell. Biochem. 2005, 272:179-185.
36. Senthilkumar S., Devaki T., Manohar M.B., Babu M.S. Effect of squalene on cyclophosphamide-induced toxicity. Clin. Chim. Acta 2006, 364:335-342.
37. Sharma N., Trikha P., Athar M., Raisuddin S. Inhibitory effect ofEmblica officinalison thein vivoclastogenicity of benzo[a]pyrene and cyclophosphamide in mice. Hum. Exp. Toxicol. 2000, 19:377-384.
38. Sheeja K., Kuttan G. Ameliorating effects of Andrographis Paniculata extract against cyclophosphamide-induced toxicity in mice. Asian Pac. J. Cancer Prev. 2006, 7:609-614.
39. Shulman H.M., McDonald G.B., Matthews D., Doney K.C. An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation. Gastroenterology 1980, 79:1178-1191.
40. Sladek N. Metabolism of cyclophosphamide by rat hepatic microsomes. Cancer Res. 1971, 1:901-908.
41. Snover D.C., Weisdorf S., Bloomer J., McGlave P., Weisdorf D. Nodular regenerative hyperplasia of the liver following bone marrow transplantation. Hepatology 1989, 9:443-448.
42. Srivastava A., Shivanandappa T. Hepatoprotective effect of the aqueous extract of the roots of Decalepis hamiltonii against ethanol-induced oxidative stress in rats. Hepatol. Res. 2006, 35:267-275.
43. Srivastava A., Shivanandappa T. Decalepis hamiltonii roots boost antioxidant status of rat liver and brain. J. Sci. Food Agric. 2009, 14:2461-2466.
44. Srivastava A., Shivanandappa T. Neuroprotective effect of Decalepis hamiltonii roots against ethanol-induced oxidative stress. Food Chem. 2010, 119:626-629.
45. Srivastava A., Shivanandappa T. Hepatoprotective effect of the root extract of Decalepis hamiltonii against carbon tetrachloride-induced oxidative stress in rats. Food Chem. 2010, 118:411-417.
46. Srivastava A., Harish R., Shivanandappa T. Novel antioxidant compounds from the aqueous extract of the roots of Decalepis hamiltonii (Wight and Arn.) and their inhibitory effect on low-density lipoprotein oxidation. J. Agric. Food Chem. 2006, 54:790-795.
47. Srivastava A., Harish Shereen R., Shivanandappa T. Antioxidant activity of the roots of Decalepis hamiltonii (Wight and Arn.). LWT-Food. Sci. Technol. 2006, 39:1059-1065.
48. Srivastava A., Rao L.J.M., Shivanandappa T. Isolation of ellagic acid from the aqueous extract of the roots of Decalepis hamiltonii: antioxidant activity and cytoprotective effect. Food Chem. 2007, 103:224-233.
49. Stankiewicz A., Skrzydlewska E., Makiela M. Effects of amifostine on liver oxidative stress caused by cyclophosphamide administration to rats. Drug Metab. Drug Interact. 2002, 19:67-82.
50. Sudharsan P.T., Mythili Y., Selvakumar E., Varalakshmi P. Cardioprotective effect of pentacyclic triterpene, lupeol and its ester on cyclophosphamide-induced oxidative stress. Hum. Exp. Toxicol. 2005, 24:313-318.
51. Tripathi D.N., Jena G.B. Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat: role of Nrf2, p53, p38 and phase-II enzymes. Mutat. Res. 2010, 696:69-80.
52. Warholm M., Guthenberg C., Bahr C.V., Mannervik B. Glutathione transferase from human liver. Methods Enzymol. 1985, 113:499-504.
53. Wasserman W.W., Fahl W.E. Functional antioxidant responsive elements. Proc. National Acad. Sci. USA 1997, 94:5361-5366.
54. Weijl N.I., Cleton F.J., Osanto S. Free radicals and antioxidants in chemotherapy-induced toxicity. Cancer Treat. Rev. 1997, 23:209-240.
55. Yousefipour Z., Ranganna K., Newaz M.A., Milton S.G. Mechanism of acrolein-induced vascular toxicity. J. Physiol. Pharmacol. 2005, 56:337-353.
56. Yuan M., Smith P.B., Brundrett R.B., Colvin M., Fenselau C. Glutathione conjugation with phosphoramide mustard and cyclophosphamide. A mechanistic study using tandem mass spectrometry. Drug Metab. Dispos. 1991, 19:625-629.