Treatment with a highly selective β1 antagonist causes dose-dependent impairment of cerebral perfusion after hemodilution in rats

Anesthesia and Analgesia

Volumn 116, Issue 3, 2013, Pages 649-662

  Hu, Tina ^a   Beattie, W Scott ^b   Mazer, C David ^a   Leong Poi, Howard ^a   Fujii, Hiroko ^a   Wilson, David F ^c   Tsui, Albert K Y ^a   Liu, Elaine ^a   Muhammad, Maimoona ^a   Baker, Andrew J ^a   Hare, Gregory M T ^a  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NEBIVOLOL;

ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; BRAIN HYPOXIA; BRAIN PERFUSION; CONTROLLED STUDY; DRUG MEGADOSE; HEART OUTPUT; HEART RATE; HEMODILUTION; HEMOGLOBIN DETERMINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; BENZOPYRANS; CEREBROVASCULAR CIRCULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOLAMINES; HEMODILUTION; MALE; MICE; MICE, INBRED C57BL; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TREATMENT OUTCOME;

EID: 84876687125     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0b013e318280e26d     Document Type: Article

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