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Volumn 296, Issue 3, 2009, Pages

Cerebral adaptations to chronic anemia in a model of erythropoietin- deficient mice exposed to hypoxia

Author keywords

Angiogenesis; Cerebral cortex; Chronic anemia; Erythropoietin; Hypoxia

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NEURONAL NITRIC OXIDE SYNTHASE; STAT5 PROTEIN; VASCULOTROPIN; HEMOGLOBIN; HIF1A PROTEIN, MOUSE; NITRIC OXIDE; RNA; VASCULOTROPIN A;

EID: 64149121692     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00119.2008     Document Type: Article
Times cited : (37)

References (61)
  • 1
    • 0029682870 scopus 로고    scopus 로고
    • Oxidative damage and tyrosine nitration from peroxynitrite
    • Beckman JS. Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol 9: 836-844, 1996.
    • (1996) Chem Res Toxicol , vol.9 , pp. 836-844
    • Beckman, J.S.1
  • 2
    • 4644310308 scopus 로고    scopus 로고
    • Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells
    • DOI 10.1182/blood-2004-02-0744
    • Beleslin-Cokic BB, Cokic VP, Yu X, Weksler BB, Schechter AN, Noguchi CT. Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Blood 104: 2073-2080, 2004. (Pubitemid 39297859)
    • (2004) Blood , vol.104 , Issue.7 , pp. 2073-2080
    • Beleslin-Cokic, B.B.1    Cokic, V.P.2    Yu, X.3    Weksler, B.B.4    Schechter, A.N.5    Noguchi, C.T.6
  • 6
    • 33746137372 scopus 로고    scopus 로고
    • Discovering erythropoietin's extra-hematopoietic functions: Biology and clinical promise
    • DOI 10.1038/sj.ki.5001546, PII 5001546
    • Brines M, Cerami A. Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise. Kidney Int 70: 246-250. 2006. (Pubitemid 44086573)
    • (2006) Kidney International , vol.70 , Issue.2 , pp. 246-250
    • Brines, M.1    Cerami, A.2
  • 7
    • 0033763820 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia
    • Chavez JC, Agani F, Pichiule P, LaManna JC. Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia. J Appl Physiol 89: 1937-1942, 2000.
    • (2000) J Appl Physiol , vol.89 , pp. 1937-1942
    • Chavez, J.C.1    Agani, F.2    Pichiule, P.3    LaManna, J.C.4
  • 9
    • 11144337759 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Regulation by hypoxic and non-hypoxic activators
    • Déry MA, Michaud MD, Richard DE. Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators. Int J Biochem Cell Biol 37: 535-540, 2005.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 535-540
    • Déry, M.A.1    Michaud, M.D.2    Richard, D.E.3
  • 10
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • DOI 10.1038/35088074
    • Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412: 641-647, 2001. (Pubitemid 32772276)
    • (2001) Nature , vol.412 , Issue.6847 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 12
    • 33344461329 scopus 로고    scopus 로고
    • Anti-Epo receptor antibodies do not predict Epo receptor expression
    • DOI 10.1182/blood-2005-10-4066
    • Elliott S, Busse L, Bass MB, Lu H, Sarosi I, Sinclair AM, Spahr C, Um M, Van G, Begley CG. Anti-Epo receptor antibodies do not predict Epo receptor expression. Blood 107: 1892-1895, 2006. (Corrigendum. Blood 107: 3454, 2006). (Pubitemid 43289368)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1892-1895
    • Elliott, S.1    Busse, L.2    Bass, M.B.3    Lu, H.4    Sarosi, I.5    Sinclair, A.M.6    Spahr, C.7    Um, M.8    Van, G.9    Begley, C.G.10
  • 13
    • 27744528319 scopus 로고    scopus 로고
    • JANUS under stress - Role of JAK/STAT signaling pathway in vascular diseases
    • DOI 10.1016/j.vph.2005.08.021, PII S1537189105001904, JAK/STAT Signaling Pathway and the Vasculature
    • Grote K, Luchtefeld M, Schieffer B. JANUS under stress - role of JAK/STAT signaling pathway in vascular diseases. Vascul Pharmacol 43: 357-363, 2005. (Pubitemid 41608760)
    • (2005) Vascular Pharmacology , vol.43 , Issue.5 , pp. 357-363
    • Grote, K.1    Luchtefeld, M.2    Schieffer, B.3
  • 15
    • 4944238852 scopus 로고    scopus 로고
    • Anaemia and the brain
    • Hare GM. Anaemia and the brain. Curr Opin Anaesthesiol 17: 363-369, 2004.
    • (2004) Curr Opin Anaesthesiol , vol.17 , pp. 363-369
    • Hare, G.M.1
  • 18
    • 33746388438 scopus 로고    scopus 로고
    • Hypoxic damage to the periventricular white matter in neonatal brain: Role of vascular endothelial growth factor, nitric oxide and excitotoxicity
    • DOI 10.1111/j.1471-4159.2006.03964.x
    • Kaur C, Sivakumar V, Ang LS, Sundaresan A. Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity. J Neurochem 98: 1200-1216, 2006. (Pubitemid 44127795)
    • (2006) Journal of Neurochemistry , vol.98 , Issue.4 , pp. 1200-1216
    • Kaur, C.1    Sivakumar, V.2    Ang, L.S.3    Sundaresan, A.4
  • 19
    • 7544221404 scopus 로고    scopus 로고
    • The role of erythropoietin in regulating angiogenesis
    • DOI 10.1016/j.ydbio.2004.08.025, PII S0012160604005780
    • Kertesz N, Wu J, Chen TH, Sucov HM, Wu H. The role of erythropoietin in regulating angiogenesis. Dev Biol 276:101-110, 2004. (Pubitemid 39452849)
    • (2004) Developmental Biology , vol.276 , Issue.1 , pp. 101-110
    • Kertesz, N.1    Wu, J.2    Chen, T.H.-P.3    Sucov, H.M.4    Wu, H.5
  • 20
    • 0032904863 scopus 로고    scopus 로고
    • Prolonged hypoxia increases vascular endothelial growth factor mRNA and protein in adult mouse brain
    • Kuo NT, Benhayon D, Przybylski RJ, Martin RJ, LaManna JC. Prolonged hypoxia increases vascular endothelial growth factor mRNA and protein in adult mouse brain. J Appl Physiol 86: 260-264, 1999. (Pubitemid 29046965)
    • (1999) Journal of Applied Physiology , vol.86 , Issue.1 , pp. 260-264
    • Kuo, N.-T.1    Benhayon, D.2    Przybylski, R.J.3    Martin, R.J.4    Lamanna, J.C.5
  • 21
    • 4644371659 scopus 로고    scopus 로고
    • Structural and functional adaptation to hypoxia in the rat brain
    • DOI 10.1242/jeb.00976
    • LaManna JC, Chavez JC, Pichiule P. Structural and functional adaptation to hypoxia in the rat brain. J Exp Biol 207: 3163-3169, 2004. (Pubitemid 39275291)
    • (2004) Journal of Experimental Biology , vol.207 , Issue.18 , pp. 3163-3169
    • Lamanna, J.C.1    Chavez, J.C.2    Pichiule, P.3
  • 22
    • 0024330873 scopus 로고
    • Changes in regional cerebral blood flow and sucrose space after 3-4 weeks of hypobaric hypoxia (0.5 ATM)
    • LaManna JC, McCracken KA, Strohl KP. Changes in regional cerebral blood flow and sucrose space after 3-4 weeks of hypobaric hypoxia (0.5 ATM). Adv Exp Med Biol 248: 471-477, 1989.
    • (1989) Adv Exp Med Biol , vol.248 , pp. 471-477
    • LaManna, J.C.1    McCracken, K.A.2    Strohl, K.P.3
  • 23
    • 0026636523 scopus 로고
    • Brain adaptation to chronic hypobaric hypoxia in rats
    • LaManna JC, Vendel LM, Farrell RM. Brain adaptation to chronic hypobaric hypoxia in rats. J Appl Physiol 72: 2238-2243, 1992.
    • (1992) J Appl Physiol , vol.72 , pp. 2238-2243
    • LaManna, J.C.1    Vendel, L.M.2    Farrell, R.M.3
  • 24
    • 0030833764 scopus 로고    scopus 로고
    • Adequacy of cerebral vascular remodeling following three weeks of hypobaric hypoxia. Examined by an integrated composite analytical model
    • Lauro KL, LaManna JC. Adequacy of cerebral vascular remodeling following three weeks of hypobaric hypoxia. Examined by an integrated composite analytical model. Adv Exp Med Biol 411: 369-376, 1997.
    • (1997) Adv Exp Med Biol , vol.411 , pp. 369-376
    • Lauro, K.L.1    LaManna, J.C.2
  • 25
    • 1642387020 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1) alpha: Its protein stability and biological functions
    • Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW. Hypoxia-inducible factor (HIF-1) alpha: its protein stability and biological functions. Exp Mol Med 36: 1-12, 2004.
    • (2004) Exp Mol Med , vol.36 , pp. 1-12
    • Lee, J.W.1    Bae, S.H.2    Jeong, J.W.3    Kim, S.H.4    Kim, K.W.5
  • 27
    • 20444430402 scopus 로고    scopus 로고
    • Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin
    • DOI 10.1161/01.STR.0000166180.91042.02
    • Liu J, Narasimhan P, Yu F, Chan PH. Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin. Stroke 36: 1264-1269, 2005. (Pubitemid 40798749)
    • (2005) Stroke , vol.36 , Issue.6 , pp. 1264-1269
    • Liu, J.1    Narasimhan, P.2    Yu, F.3    Chan, P.H.4
  • 28
    • 20744455084 scopus 로고    scopus 로고
    • Evidence of a decrease in nitric oxide-storage molecules following acute hypoxia and/or hypobaria, by means of chemiluminescence analysis
    • DOI 10.1016/j.niox.2005.05.003, PII S1089860305000686
    • López-Ramos, JC, Martínez-Romero R, Molina F, Cañuelo A, Martínez-Lara E, Siles E, Peinado MA. Evidence of a decrease in nitric oxide-storage molecules following acute hypoxia and/or hypobaria, by means of chemiluminescence analysis. Nitric Oxide 13: 62-67, 2005. (Pubitemid 40853970)
    • (2005) Nitric Oxide - Biology and Chemistry , vol.13 , Issue.1 , pp. 62-67
    • Lopez-Ramos, J.C.1    Martinez-Romero, R.2    Molina, F.3    Canuelo, A.4    Martinez-Lara, E.5    Siles, E.6    Peinado, M.A.7
  • 32
    • 4644318784 scopus 로고    scopus 로고
    • Erythropoietin and the hypoxic brain
    • Marti HH. Erythropoietin and the hypoxic brain. J Exp Biol 207: 3233-3242, 2004.
    • (2004) J Exp Biol , vol.207 , pp. 3233-3242
    • Marti, H.H.1
  • 36
    • 38849206183 scopus 로고    scopus 로고
    • Recent trends in erythropoietin-mediated neuroprotection
    • McPherson RJ, Juul SE. Recent trends in erythropoietin-mediated neuroprotection. Int J Dev Neurosci 26: 103-111, 2008.
    • (2008) Int J Dev Neurosci , vol.26 , pp. 103-111
    • McPherson, R.J.1    Juul, S.E.2
  • 37
    • 0025784834 scopus 로고
    • Endogenous nitric oxide: Physiology, pathology and clinical relevance
    • Moncada S, Higgs EA. Endogenous nitric oxide: physiology, pathology and clinical relevance. Eur J Clin Invest 21: 361-374, 1991.
    • (1991) Eur J Clin Invest , vol.21 , pp. 361-374
    • Moncada, S.1    Higgs, E.A.2
  • 38
    • 0028961172 scopus 로고
    • Mechanisms of hypoxic cerebral vasodilatation
    • Pearce WJ. Mechanisms of hypoxic cerebral vasodilatation. Pharmacol Ther 65: 75-91, 1995.
    • (1995) Pharmacol Ther , vol.65 , pp. 75-91
    • Pearce, W.J.1
  • 39
    • 0028868667 scopus 로고
    • Role of nitric oxide, adenosine, N-methyl-D-aspartate receptors, and neuronal activation in hypoxia-induced pial arteriolar dilation in rats
    • Pelligrino DA, Wang Q, Koenig HM, Albrecht RF. Role of nitric oxide, adenosine, N-methyl-D-aspartate receptors, and neuronal activation in hypoxia-induced pial arteriolar dilation in rats. Brain Res 704: 61-70, 1995.
    • (1995) Brain Res , vol.704 , pp. 61-70
    • Pelligrino, D.A.1    Wang, Q.2    Koenig, H.M.3    Albrecht, R.F.4
  • 40
    • 1842478183 scopus 로고    scopus 로고
    • Hypoxic Regulation of Angiopoietin-2 Expression in Endothelial Cells
    • DOI 10.1074/jbc.M305146200
    • Pichiule P, Chavez JC, LaManna JC. Hypoxic regulation of angiopoietin-2 expression in endothelial cells. J Biol Chem 279: 12171-12180, 2004. (Pubitemid 38445782)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.13 , pp. 12171-12180
    • Pichiule, P.1    Chavez, J.C.2    Lamanna, J.C.3
  • 42
    • 0036707853 scopus 로고    scopus 로고
    • Angiopoietin-2 and rat brain capillary remodeling during adaptation and deadaptation to prolonged mild hypoxia
    • Pichiule P, LaManna JC. Angiopoietin-2 and rat brain capillary remodeling during adaptation and deadaptation to prolonged mild hypoxia. J Appl Physiol 93: 1131-1139, 2002.
    • (2002) J Appl Physiol , vol.93 , pp. 1131-1139
    • Pichiule, P.1    LaManna, J.C.2
  • 44
    • 0034282388 scopus 로고    scopus 로고
    • Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1 alpha in vascular smooth muscle cells
    • Richard DE, Berra E, Pouyssegur J. Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1 alpha in vascular smooth muscle cells. J Biol Chem 275: 26765-26771, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 26765-26771
    • Richard, D.E.1    Berra, E.2    Pouyssegur, J.3
  • 45
    • 0036846795 scopus 로고    scopus 로고
    • Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain
    • Schoch HJ, Fischer S, Marti HH. Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain. Brain 125: 2549-2557, 2002. (Pubitemid 35303512)
    • (2002) Brain , vol.125 , Issue.11 , pp. 2549-2557
    • Schoch, H.J.1    Fischer, S.2    Marti, H.H.3
  • 46
    • 8344237449 scopus 로고    scopus 로고
    • Hydroxylation of HIF-1: Oxygen sensing at the molecular level
    • Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 19: 176-182, 2004.
    • (2004) Physiology , vol.19 , pp. 176-182
    • Semenza, G.L.1
  • 47
    • 33749254959 scopus 로고    scopus 로고
    • Effects of acute hypobaric hypoxia on the nitric oxide system of the rat cerebral cortex: Protective role of nitric oxide inhibitors
    • DOI 10.1016/j.neuroscience.2006.07.046, PII S0306452206010645
    • Serrano J, Encinas JM, Fernandez AP, Rodrigo J, Martinez A. Effects of acute hypobaric hypoxia on the nitric oxide system of the rat cerebral cortex: Protective role of nitric oxide inhibitors. Neuroscience 142: 799-808, 2006. (Pubitemid 44485925)
    • (2006) Neuroscience , vol.142 , Issue.3 , pp. 799-808
    • Serrano, J.1    Encinas, J.M.2    Fernandez, A.P.3    Rodrigo, J.4    Martinez, A.5
  • 49
    • 34547851589 scopus 로고    scopus 로고
    • Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia
    • DOI 10.1113/jphysiol.2007.133454
    • Soliz J, Gassmann M, Joseph V. Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia. J Physiol 583: 329-336, 2007. (Pubitemid 47244262)
    • (2007) Journal of Physiology , vol.583 , Issue.1 , pp. 329-336
    • Soliz, J.1    Gassmann, M.2    Joseph, V.3
  • 51
    • 4444278918 scopus 로고    scopus 로고
    • Hypoxia-ischemia affects erythropoietin and erythropoietin receptor expression pattern in the neonatal rat brain
    • DOI 10.1016/j.brainres.2004.06.057, PII S000689930401039X
    • Spandou E, Papoutsopoulou S, Soubasi V, Karkavelas G, Simeonidou C, Kremenopoulos G, Guiba-Tziampiri O. Hypoxia-ischemia affects erythropoietin and erythropoietin receptor expression pattern in the neonatal rat brain. Brain Res 1021: 167-172, 2004. (Pubitemid 39165793)
    • (2004) Brain Research , vol.1021 , Issue.2 , pp. 167-172
    • Spandou, E.1    Papoutsopoulou, S.2    Soubasi, V.3    Karkavelas, G.4    Simeonidou, C.5    Kremenopoulos, G.6    Guiba-Tziampiri, O.7
  • 52
    • 0030726018 scopus 로고    scopus 로고
    • Cerebral blood flow during hypoxemia and hemodilution in rabbits: Different roles for nitric oxide?
    • Todd MM, Farrell S, Wu B. Cerebral blood flow during hypoxemia and hemodilution in rabbits: different roles for nitric oxide? J Cereb Blood Flow Metab 17: 1319-1325, 1997. (Pubitemid 27520123)
    • (1997) Journal of Cerebral Blood Flow and Metabolism , vol.17 , Issue.12 , pp. 1319-1325
    • Todd, M.M.1    Farrell, S.2    Wu, B.3
  • 53
    • 40049108004 scopus 로고    scopus 로고
    • HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam
    • Trollmann R, Schneider J, Keller S, Strasser K, Wenzel D, Rascher W, Ogunshola OO, Gassmann M. HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam. Brain Res 1199: 27-36, 2008.
    • (2008) Brain Res , vol.1199 , pp. 27-36
    • Trollmann, R.1    Schneider, J.2    Keller, S.3    Strasser, K.4    Wenzel, D.5    Rascher, W.6    Ogunshola, O.O.7    Gassmann, M.8
  • 55
    • 34247893743 scopus 로고    scopus 로고
    • Cerebral angiogenic factors, angiogenesis, and physiological response to chronic hypoxia differ among four commonly used mouse strains
    • DOI 10.1152/japplphysiol.00909.2006
    • Ward NL, Moore E, Noon K, Spassil N, Keenan E, Ivanco TL, LaManna JC. Cerebral angiogenic factors, angiogenesis, and physiological response to chronic hypoxia differ among four commonly used mouse strains. J Appl Physiol 102: 1927-1935, 2007. (Pubitemid 46701964)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.5 , pp. 1927-1935
    • Ward, N.L.1    Moore, E.2    Noon, K.3    Spassil, N.4    Keenan, E.5    Ivanco, T.L.6    Lamanna, J.C.7
  • 56
    • 33646346397 scopus 로고    scopus 로고
    • Chronic hypoxia and the cerebral circulation
    • DOI 10.1152/japplphysiol.00940.2005
    • Xu K, Lamanna JC. Chronic hypoxia and the cerebral circulation. J Appl Physiol 100: 725-730, 2006. (Pubitemid 43671631)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.2 , pp. 725-730
    • Xu, K.1    Lamanna, J.C.2
  • 59
    • 21544484345 scopus 로고    scopus 로고
    • Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells
    • DOI 10.1016/j.brainres.2005.05.037, PII S0006899305007225
    • Yamasaki M, Mishima HK, Yamashita H, Kashiwagi K, Murata K, Minamoto A, Inaba T. Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells. Brain Res 1050: 15-26, 2005. (Pubitemid 40922713)
    • (2005) Brain Research , vol.1050 , Issue.1-2 , pp. 15-26
    • Yamasaki, M.1    Mishima, H.K.2    Yamashita, H.3    Kashiwagi, K.4    Murata, K.5    Minamoto, A.6    Inaba, T.7
  • 60
    • 0032566597 scopus 로고    scopus 로고
    • Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis
    • DOI 10.1074/jbc.273.39.25381
    • Yasuda Y, Masuda S, Chikuma M, Inoue K, Nagao M, Sasaki R. Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis. J Biol Chem 273: 25381-25387, 1998. (Pubitemid 28443305)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.39 , pp. 25381-25387
    • Yasuda, Y.1    Masuda, S.2    Chikuma, M.3    Inoue, K.4    Nagao, M.5    Sasaki, R.6
  • 61
    • 0034627231 scopus 로고    scopus 로고
    • iNOS expression inhibits hypoxia-inducible factor-1 activity
    • Yin JH, Yang DI, Ku G, Hsu CY. iNOS expression inhibits hypoxia-inducible factor-1 activity. Biochem Biophys Res Commun 279: 30-34, 2000.
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 30-34
    • Yin, J.H.1    Yang, D.I.2    Ku, G.3    Hsu, C.Y.4


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