Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology

Acta Neuropathologica

Volumn 125, Issue 4, 2013, Pages 565-579

  Hara, Makoto ^a,b   Hirokawa, Katsuiku ^c   Kamei, Satoshi ^b   Uchihara, Toshiki ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Nakano General Hospital   (Japan)

Author keywords

AD pathology; Human brain; Isoform; Neuronal morphology; Tau expression

Indexed keywords

ISOPROTEIN; PROTEIN ANTIBODY; TAU PROTEIN;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; BRAIN REGION; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; DENDRITE; DENTATE HILUS; DISEASE ACTIVITY; ENTORHINAL CORTEX; FEMALE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SOMATIC CELL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; DISEASE PROGRESSION; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MIDDLE AGED; NEUROFIBRILLARY TANGLES; NEURONS; PROTEIN ISOFORMS; TAU PROTEINS;

EID: 84876674149     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-013-1097-6     Document Type: Article

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