Linkage-dependent contribution of repeat peptides to self-aggregation of three- or four-repeat microtubule-binding domains in tau protein

FEBS Journal

Volumn 275, Issue 7, 2008, Pages 1529-1539

  Okuyama, Kayoko ^a   Nishiura, Chisato ^a   Mizushima, Fumie ^a   Minoura, Katsuhiko ^a   Sumida, Miho ^b   Taniguchi, Taizo ^b   Tomoo, Koji ^a   Ishida, Toshimasa ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Behavioral and Medical Sciences Research Consortium   (Japan)

Author keywords

Aggregation; CD; Fluorescence; Repeat linkage dependence; Tau microtubule binding domain

Indexed keywords

DIRECT YELLOW 7; PEPTIDE DERIVATIVE; TAU PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; CIRCULAR DICHROISM; ELECTRON MICROSCOPY; FLUORESCENCE; IN VITRO STUDY; MICROTUBULE; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; WILD TYPE;

AMINO ACID SEQUENCE; HEPARIN; HUMANS; MICROFILAMENTS; MICROTUBULES; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; TAU PROTEINS;

EID: 40749131329     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06312.x     Document Type: Article

References (25)

1. Goedert M, Wischik CM, Crowther RA, Walker JE Klug A (1988) Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer's disease: identification as the microtubule-associated protein tau. Proc Natl Acad Sci USA 85, 4051 4055.
2. Lee G, Cowan N Kirschner M (1988) The primary structure and heterogeneity of tau protein from mouse brain. Science 239, 285 288.
3. Goedert M, Spillantini MG, Jakes R, Rutherford D Crowther RA (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3, 519 526.
4. Friedhoff F, Von Bergen M, Mandelkow EM Mandelkow E (1998) A nucleated assembly mechanism of Alzheimer paired helical filaments. Proc Natl Acad Sci USA 95, 15712 15717.
5. Wille H, Drewes G, Biernat J, Mandelkow EM Mandelkow E (1992) Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro. J Cell Biol 118, 573 584.
6. Barghorn S Mandelkow E (2002) Toward a unified scheme for the aggregation of tau into Alzheimer paired helical filament. Biochemistry 41, 14885 14896.
7. Gamblin TC, Berry RW Binder LI (2003) Modeling tau polymerization in vitro: a review and synthesis. Biochemistry 42, 15009 15017.
8. Barghorn S, Davies P Mandelkow E (2004) Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on β-structure in the core domain. Biochemistry 43, 1694 1703.
9. Yao TM, Tomoo K, Ishida T, Hasegawa H, Sasaki M Taniguchi T (2003) Aggregation analysis of the microtubule-binding domain in tau protein by spectroscopic methods. J Biochem 134, 91 99.
10. Perez M, Valpuesta JM, Medina M, Montejo de Garcini E Avila J (1996) Polymerization of τ into filament in the presence of heparin: the minimal sequence required for τ-τ interaction. J Neurochem 67, 1183 1190.
11. 1H NMR spectroscopy. Biochem Biophys Res Commun 294, 210 214.
12. 1H-NMR spectroscopy and molecular modeling calculation. Bull Chem Soc Jpn 76, 1617 1624.
13. Minoura K, Yao TM, Tomoo K, Sumida M, Sasaki M, Taniguchi T Ishida T (2004) Differential associational and conformational behaviours between the second and third repeat fragments in the tau microtubule-binding domain. Eur J Biochem 271, 545 552.
14. Hiraoka S, Yao TM, Minoura K, Tomoo K, Sumida M, Taniguchi T Ishida T (2004) Conformational transition state is responsible for assembly of microtubule-binding domain of tau protein. Biochem Biophys Res Commun 315, 659 663.
15. Minoura K, Mizushima F, Tokimasa M, Hiraoka S, Tomoo K, Sumida M, Taniguchi T Ishida T (2005) Structural evaluation of conformational transition state responsible for self-assembly of tau microtubule-binding domain. Biochem Biophys Res Commun 327, 1100 1104.
16. Tokimasa M, Minoura K, Hiraoka S, Tomoo K, Sumida M, Taniguchi T Ishida T (2005) Importance of local structures of second and third repeat fragments of microtubule-binding domain for tau filament formation. FEBS Lett 579, 3481 3486.
17. Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ Crowther RA (1996) Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulfated glycosaminoglycans. Nature 383, 550 553.
18. Kampers T, Friedhoff P, Biernat J Mandelkow EM (1996) RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments. FEBS Lett 399, 344 349.
19. Friedhoff P, Schneider A, Mandelkow EM Mandelkow M (1998) Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution. Biochemistry 37, 10223 10230.
20. Mizushima F, Minoura K, Tomoo K, Sumida M, Taniguchi T Ishida T (2006) Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain. Biochem Biophys Res Commun 343, 712 718.
21. Tomoo K, Yao TM, Minoura K, Hiraoka S, Sumida M, Taniguchi T Ishida T (2005) Possible role of each repeat structure of the microtubule-binding domain of the tau protein in in vitro aggregation. J Biochem 1348, 413 423.
22. Mizushima F, Minoura K, Tomoo K, Sumida M, Taniguchi T Ishida T (2007) Marked difference between self-aggregations of first and fourth repeat peptides on tau microtubule-binding domain in acidic solution. J Biochem 142, 49 64.
23. 7GTP complex. J Biochem 123, 157 161.
24. Sreerama N Woody RW (2000) Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Anal Biochem 287, 252 260.
25. Sreerama N, Venyaminov SY Woody RW (2001) Analysis of protein circular dichroism spectra based on the tertiary structure classification. Anal Biochem 299, 271 274.