A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lungs

Journal of Pharmacology and Experimental Therapeutics

Volumn 345, Issue 2, 2013, Pages 284-296

  Lee, Intae ^a   Dodia, Chandra ^a   Chatterjee, Shampa ^a   Zagorski, John ^a   Mesaros, Clementina ^b   Blair, Ian A ^b   Feinstein, Sheldon I ^a   Jain, Mahendra ^c,d   Fisher, Aron B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Center for Cancer Pharmacology and Excellence in Environmental Toxicology   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 HEXADECYL 3 TRIFLUOROETHYLGLYCERO SN 2 PHOSPHOMETHANOL; CYTOSOLIC PHOSPHOLIPASE A2; ENZYME INHIBITOR; LIPOSOME; MJ 33; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; HEMATOCRIT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; KIDNEY; LIPID OXIDATION; LIQUID CHROMATOGRAPHY; LIVER; LUNG; MASS SPECTROMETRY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; REPERFUSION INJURY; SYMPTOMATOLOGY; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; CELL PROLIFERATION; CELL SEPARATION; CELL SURVIVAL; CELLS, CULTURED; ENZYME INHIBITORS; GLYCEROPHOSPHATES; HEMATOCRIT; INJECTIONS, INTRAVENOUS; INJECTIONS, SPINAL; LIPOSOMES; LUNG; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH OXIDASE; OXIDATIVE STRESS; PHOSPHOLIPASES A2; REACTIVE OXYGEN SPECIES;

EID: 84876574086     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.201079     Document Type: Article

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