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Volumn 8, Issue 4, 2013, Pages

Local Mechanical Stimuli Regulate Bone Formation and Resorption in Mice at the Tissue Level

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BONE REMODELING; CONTROLLED STUDY; FEMALE; FINITE ELEMENT ANALYSIS; IMAGE ANALYSIS; IN VIVO STUDY; MECHANICAL STIMULATION; MICRO-COMPUTED TOMOGRAPHY; MOLECULAR IMAGING; MOUSE; MUSCULOSKELETAL FUNCTION; MUSCULOSKELETAL SYSTEM PARAMETERS; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OVARIECTOMY;

EID: 84876516474     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062172     Document Type: Article
Times cited : (180)

References (51)
  • 2
    • 0023173665 scopus 로고
    • The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents
    • Frost HM, (1987) The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents. Bone Miner 2: 73-85.
    • (1987) Bone Miner , vol.2 , pp. 73-85
    • Frost, H.M.1
  • 3
    • 0025872871 scopus 로고
    • A noninvasive, in vivo model for studying strain adaptive bone modeling
    • Turner CH, Akhter MP, Raab DM, Kimmel DB, Recker RR, (1991) A noninvasive, in vivo model for studying strain adaptive bone modeling. Bone 12: 73-79.
    • (1991) Bone , vol.12 , pp. 73-79
    • Turner, C.H.1    Akhter, M.P.2    Raab, D.M.3    Kimmel, D.B.4    Recker, R.R.5
  • 5
    • 33748166972 scopus 로고    scopus 로고
    • Biomechanical and molecular regulation of bone remodeling
    • Robling AG, Castillo AB, Turner CH, (2006) Biomechanical and molecular regulation of bone remodeling. Annu Rev Biomed Eng 8: 455-498.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 455-498
    • Robling, A.G.1    Castillo, A.B.2    Turner, C.H.3
  • 8
    • 0015545246 scopus 로고
    • Analysis of surface bone strain in the calcaneus of sheep during normal locomotion. Strain analysis of the calcaneus
    • Lanyon LE, (1973) Analysis of surface bone strain in the calcaneus of sheep during normal locomotion. Strain analysis of the calcaneus. J Biomech 6: 41-49.
    • (1973) J Biomech , vol.6 , pp. 41-49
    • Lanyon, L.E.1
  • 9
    • 0027055120 scopus 로고
    • Control of Bone Architecture by Functional Load Bearing
    • Lanyon LE, (1992) Control of Bone Architecture by Functional Load Bearing. Journal of Bone and Mineral Research 7: S369-S375.
    • (1992) Journal of Bone and Mineral Research , vol.7
    • Lanyon, L.E.1
  • 11
    • 28844442933 scopus 로고    scopus 로고
    • Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element
    • De Souza RL, Matsuura M, Eckstein F, Rawlinson SCF, Lanyon LE, et al. (2005) Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element. Bone 37: 810-818.
    • (2005) Bone , vol.37 , pp. 810-818
    • De Souza, R.L.1    Matsuura, M.2    Eckstein, F.3    Rawlinson, S.C.F.4    Lanyon, L.E.5
  • 12
    • 61549133522 scopus 로고    scopus 로고
    • A novel in vivo mouse model for mechanically stimulated bone adaptation - a combined experimental and computational validation study
    • Webster DJ, Morley PL, van Lenthe GH, Müller R, (2008) A novel in vivo mouse model for mechanically stimulated bone adaptation- a combined experimental and computational validation study. Comput Methods Biomech Biomed Engin 11: 435-441.
    • (2008) Comput Methods Biomech Biomed Engin , vol.11 , pp. 435-441
    • Webster, D.J.1    Morley, P.L.2    van Lenthe, G.H.3    Müller, R.4
  • 13
    • 78649875060 scopus 로고    scopus 로고
    • Mechanical loading of mouse caudal vertebrae increases trabecular and cortical bone mass-dependence on dose and genotype
    • Webster D, Wasserman E, Ehrbar M, Weber F, Bab I, et al. (2010) Mechanical loading of mouse caudal vertebrae increases trabecular and cortical bone mass-dependence on dose and genotype. Biomech Model Mechanobiol 9: 737-747.
    • (2010) Biomech Model Mechanobiol , vol.9 , pp. 737-747
    • Webster, D.1    Wasserman, E.2    Ehrbar, M.3    Weber, F.4    Bab, I.5
  • 14
    • 23844478669 scopus 로고    scopus 로고
    • The effect of reloading on bone volume, osteoblast number, and osteoprogenitor characteristics: Studies in hind limb unloaded rats
    • Basso N, Jia YH, Bellows CG, Heersche JNM, (2005) The effect of reloading on bone volume, osteoblast number, and osteoprogenitor characteristics: Studies in hind limb unloaded rats. Bone 37: 370-378.
    • (2005) Bone , vol.37 , pp. 370-378
    • Basso, N.1    Jia, Y.H.2    Bellows, C.G.3    Heersche, J.N.M.4
  • 15
    • 20444421878 scopus 로고    scopus 로고
    • Loading induces site-specific increases in mineral content assessed by microcomputed tomography of the mouse tibia
    • Fritton JC, Myers ER, Wright TM, van der Meulen MCH, (2005) Loading induces site-specific increases in mineral content assessed by microcomputed tomography of the mouse tibia. Bone 36: 1030-1038.
    • (2005) Bone , vol.36 , pp. 1030-1038
    • Fritton, J.C.1    Myers, E.R.2    Wright, T.M.3    van der Meulen, M.C.H.4
  • 16
    • 81355127344 scopus 로고    scopus 로고
    • Mouse tail vertebrae adapt to cyclic mechanical loading by increasing bone formation rate and decreasing bone resorption rate as shown by time-lapsed in vivo imaging of dynamic bone morphometry
    • Lambers FM, Schulte FA, Kuhn G, Webster DJ, Müller R, (2011) Mouse tail vertebrae adapt to cyclic mechanical loading by increasing bone formation rate and decreasing bone resorption rate as shown by time-lapsed in vivo imaging of dynamic bone morphometry. Bone 49: 1340-1350.
    • (2011) Bone , vol.49 , pp. 1340-1350
    • Lambers, F.M.1    Schulte, F.A.2    Kuhn, G.3    Webster, D.J.4    Müller, R.5
  • 17
    • 0034621881 scopus 로고    scopus 로고
    • Effects of mechanical forces on maintenance and adaptation of form in trabecular bone
    • Huiskes R, Ruimerman R, van Lenthe GH, Janssen JD, (2000) Effects of mechanical forces on maintenance and adaptation of form in trabecular bone. Nature 405: 704-706.
    • (2000) Nature , vol.405 , pp. 704-706
    • Huiskes, R.1    Ruimerman, R.2    van Lenthe, G.H.3    Janssen, J.D.4
  • 18
    • 0023488581 scopus 로고
    • Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, et al. (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2: 595-610.
    • (1987) J Bone Miner Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5
  • 19
    • 0344011532 scopus 로고    scopus 로고
    • Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment
    • Kim CH, Takai E, Zhou H, von Stechow D, Müller R, et al. (2003) Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment. J Bone Miner Res 18: 2116-2125.
    • (2003) J Bone Miner Res , vol.18 , pp. 2116-2125
    • Kim, C.H.1    Takai, E.2    Zhou, H.3    von Stechow, D.4    Müller, R.5
  • 20
    • 0034785612 scopus 로고    scopus 로고
    • Trabecular surface remodeling simulation for cancellous bone using microstructural voxel finite element models
    • Adachi T, Tsubota K, Tomita Y, Hollister SJ, (2001) Trabecular surface remodeling simulation for cancellous bone using microstructural voxel finite element models. J Biomech Eng 123: 403-409.
    • (2001) J Biomech Eng , vol.123 , pp. 403-409
    • Adachi, T.1    Tsubota, K.2    Tomita, Y.3    Hollister, S.J.4
  • 21
    • 13844274948 scopus 로고    scopus 로고
    • A theoretical framework for strain-related trabecular bone maintenance and adaptation
    • Ruimerman R, Hilbers P, van Rietbergen B, Huiskes R, (2005) A theoretical framework for strain-related trabecular bone maintenance and adaptation. J Biomech 38: 931-941.
    • (2005) J Biomech , vol.38 , pp. 931-941
    • Ruimerman, R.1    Hilbers, P.2    van Rietbergen, B.3    Huiskes, R.4
  • 23
    • 84870389562 scopus 로고    scopus 로고
    • Strain-adaptive in silico modeling of bone adaptation - A computer simulation validated by in vivo micro-computed tomography data
    • Schulte FA, Zwahlen A, Lambers FM, Kuhn G, Ruffoni D, et al. (2013) Strain-adaptive in silico modeling of bone adaptation- A computer simulation validated by in vivo micro-computed tomography data. Bone 52: 485-492.
    • (2013) Bone , vol.52 , pp. 485-492
    • Schulte, F.A.1    Zwahlen, A.2    Lambers, F.M.3    Kuhn, G.4    Ruffoni, D.5
  • 25
    • 79751536870 scopus 로고    scopus 로고
    • In vivo micro-computed tomography allows direct three-dimensional quantification of both bone formation and bone resorption parameters using time-lapsed imaging
    • Schulte FA, Lambers FM, Kuhn G, Müller R, (2011) In vivo micro-computed tomography allows direct three-dimensional quantification of both bone formation and bone resorption parameters using time-lapsed imaging. Bone 48: 433-442.
    • (2011) Bone , vol.48 , pp. 433-442
    • Schulte, F.A.1    Lambers, F.M.2    Kuhn, G.3    Müller, R.4
  • 27
    • 84857053721 scopus 로고    scopus 로고
    • Longitudinal assessment of in vivo bone dynamics in a mouse tail model of postmenopausal osteoporosis
    • Lambers FM, Kuhn G, Schulte FA, Koch K, Müller R, (2011) Longitudinal assessment of in vivo bone dynamics in a mouse tail model of postmenopausal osteoporosis. Calcif Tissue Int 90: 108-119.
    • (2011) Calcif Tissue Int , vol.90 , pp. 108-119
    • Lambers, F.M.1    Kuhn, G.2    Schulte, F.A.3    Koch, K.4    Müller, R.5
  • 28
    • 0031647592 scopus 로고    scopus 로고
    • A pyramid approach to subpixel registration based on intensity
    • Thevenaz P, Ruttimann UE, Unser M, (1998) A pyramid approach to subpixel registration based on intensity. IEEE Trans Image Process 7: 27-41.
    • (1998) IEEE Trans Image Process , vol.7 , pp. 27-41
    • Thevenaz, P.1    Ruttimann, U.E.2    Unser, M.3
  • 29
    • 77954756294 scopus 로고    scopus 로고
    • Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
    • Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, et al. (2010) Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res 25: 1468-1486.
    • (2010) J Bone Miner Res , vol.25 , pp. 1468-1486
    • Bouxsein, M.L.1    Boyd, S.K.2    Christiansen, B.A.3    Guldberg, R.E.4    Jepsen, K.J.5
  • 31
    • 0033811529 scopus 로고    scopus 로고
    • If bone is the answer, then what is the question?
    • Huiskes R, (2000) If bone is the answer, then what is the question? J Anat 197 (Pt 2): 145-156.
    • (2000) J Anat , vol.197 , Issue.Pt 2 , pp. 145-156
    • Huiskes, R.1
  • 33
    • 0025486317 scopus 로고
    • An approach for time-dependent bone modeling and remodeling-theoretical development
    • Beaupre GS, Orr TE, Carter DR, (1990) An approach for time-dependent bone modeling and remodeling-theoretical development. J Orthop Res 8: 651-661.
    • (1990) J Orthop Res , vol.8 , pp. 651-661
    • Beaupre, G.S.1    Orr, T.E.2    Carter, D.R.3
  • 34
    • 35748932852 scopus 로고    scopus 로고
    • R Development Core Team, Vienna, Austria: R Foundation for Statistical Computing
    • R Development Core Team (2007) R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing.
    • (2007) R: A language and environment for statistical computing
  • 35
    • 56749177508 scopus 로고    scopus 로고
    • Postpubertal architectural developmental patterns differ between the L3 vertebra and proximal tibia in three inbred strains of mice
    • Buie HR, Moore CP, Boyd SK, (2008) Postpubertal architectural developmental patterns differ between the L3 vertebra and proximal tibia in three inbred strains of mice. J Bone Miner Res 23: 2048-2059.
    • (2008) J Bone Miner Res , vol.23 , pp. 2048-2059
    • Buie, H.R.1    Moore, C.P.2    Boyd, S.K.3
  • 36
    • 77953198416 scopus 로고    scopus 로고
    • Age-related changes in bone structure and strength in female and male BALB/c mice
    • Willinghamm MD, Brodt MD, Lee KL, Stephens AL, Ye J, et al. (2010) Age-related changes in bone structure and strength in female and male BALB/c mice. Calcif Tissue Int 86: 470-483.
    • (2010) Calcif Tissue Int , vol.86 , pp. 470-483
    • Willinghamm, M.D.1    Brodt, M.D.2    Lee, K.L.3    Stephens, A.L.4    Ye, J.5
  • 37
    • 84890569843 scopus 로고    scopus 로고
    • Bone structure and strength adapt to long-term cyclic overloading in an in vivo mouse model
    • Lambers FM, Koch K, Kuhn G, Weigt C, Schulte F, et al. (2012) Bone structure and strength adapt to long-term cyclic overloading in an in vivo mouse model. J Biomech 45: S89.
    • (2012) J Biomech , vol.45
    • Lambers, F.M.1    Koch, K.2    Kuhn, G.3    Weigt, C.4    Schulte, F.5
  • 38
    • 0036140080 scopus 로고    scopus 로고
    • Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression
    • Parfitt AM, (2002) Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression. Bone 30: 5-7.
    • (2002) Bone , vol.30 , pp. 5-7
    • Parfitt, A.M.1
  • 39
    • 0036179760 scopus 로고    scopus 로고
    • Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction
    • Gross TS, Srinivasan S, Liu CC, Clemens TL, Bain SD, (2002) Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction. J Bone Miner Res 17: 493-501.
    • (2002) J Bone Miner Res , vol.17 , pp. 493-501
    • Gross, T.S.1    Srinivasan, S.2    Liu, C.C.3    Clemens, T.L.4    Bain, S.D.5
  • 40
    • 0021848241 scopus 로고
    • Regulation of bone mass by mechanical strain magnitude
    • Rubin CT, Lanyon LE, (1985) Regulation of bone mass by mechanical strain magnitude. Calcif Tissue Int 37: 411-417.
    • (1985) Calcif Tissue Int , vol.37 , pp. 411-417
    • Rubin, C.T.1    Lanyon, L.E.2
  • 41
    • 0030995311 scopus 로고    scopus 로고
    • Strain gradients correlate with sites of periosteal bone formation
    • Gross TS, Edwards JL, McLeod KJ, Rubin CT, (1997) Strain gradients correlate with sites of periosteal bone formation. J Bone Miner Res 12: 982-988.
    • (1997) J Bone Miner Res , vol.12 , pp. 982-988
    • Gross, T.S.1    Edwards, J.L.2    McLeod, K.J.3    Rubin, C.T.4
  • 42
    • 84864139453 scopus 로고    scopus 로고
    • Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition
    • Sugiyama T, Meakin LB, Browne WJ, Galea GL, Price JS, et al. (2012) Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition. J Bone Miner Res 27: 1784-1793.
    • (2012) J Bone Miner Res , vol.27 , pp. 1784-1793
    • Sugiyama, T.1    Meakin, L.B.2    Browne, W.J.3    Galea, G.L.4    Price, J.S.5
  • 43
    • 84875308404 scopus 로고    scopus 로고
    • Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass
    • Ellman R, Spatz J, Cloutier A, Palme R, Christiansen B, et al. (2012) Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass. J Bone Miner Res.
    • (2012) J Bone Miner Res
    • Ellman, R.1    Spatz, J.2    Cloutier, A.3    Palme, R.4    Christiansen, B.5
  • 44
    • 0036889272 scopus 로고    scopus 로고
    • Functional adaptation of cancellous bone in human proximal femur predicted by trabecular surface remodeling simulation toward uniform stress state
    • Tsubota K, Adachi T, Tomita Y, (2002) Functional adaptation of cancellous bone in human proximal femur predicted by trabecular surface remodeling simulation toward uniform stress state. J Biomech 35: 1541-1551.
    • (2002) J Biomech , vol.35 , pp. 1541-1551
    • Tsubota, K.1    Adachi, T.2    Tomita, Y.3
  • 46
    • 0028066776 scopus 로고
    • Mechanical loading thresholds for lamellar and woven bone formation
    • Turner CH, Forwood MR, Rho JY, Yoshikawa T, (1994) Mechanical loading thresholds for lamellar and woven bone formation. J Bone Miner Res 9: 87-97.
    • (1994) J Bone Miner Res , vol.9 , pp. 87-97
    • Turner, C.H.1    Forwood, M.R.2    Rho, J.Y.3    Yoshikawa, T.4
  • 47
    • 0035192335 scopus 로고    scopus 로고
    • Mechanical loading of diaphyseal bone in vivo: the strain threshold for an osteogenic response varies with location
    • Hsieh YF, Robling AG, Ambrosius WT, Burr DB, Turner CH, (2001) Mechanical loading of diaphyseal bone in vivo: the strain threshold for an osteogenic response varies with location. J Bone Miner Res 16: 2291-2297.
    • (2001) J Bone Miner Res , vol.16 , pp. 2291-2297
    • Hsieh, Y.F.1    Robling, A.G.2    Ambrosius, W.T.3    Burr, D.B.4    Turner, C.H.5
  • 48
    • 0033949624 scopus 로고    scopus 로고
    • Time course for bone formation with long-term external mechanical loading
    • Cullen DM, Smith RT, Akhter MP, (2000) Time course for bone formation with long-term external mechanical loading. J Appl Physiol 88: 1943-1948.
    • (2000) J Appl Physiol , vol.88 , pp. 1943-1948
    • Cullen, D.M.1    Smith, R.T.2    Akhter, M.P.3
  • 49
    • 0036721591 scopus 로고    scopus 로고
    • Estrogen receptor-related receptor alpha impinges on the estrogen axis in bone: potential function in osteoporosis
    • Bonnelye E, Kung V, Laplace C, Galson DL, Aubin JE, (2002) Estrogen receptor-related receptor alpha impinges on the estrogen axis in bone: potential function in osteoporosis. Endocrinology 143: 3658-3670.
    • (2002) Endocrinology , vol.143 , pp. 3658-3670
    • Bonnelye, E.1    Kung, V.2    Laplace, C.3    Galson, D.L.4    Aubin, J.E.5
  • 50
    • 33746451702 scopus 로고    scopus 로고
    • Osteocytes use estrogen receptor alpha to respond to strain but their ERalpha content is regulated by estrogen
    • Zaman G, Jessop HL, Muzylak M, De Souza RL, Pitsillides AA, et al. (2006) Osteocytes use estrogen receptor alpha to respond to strain but their ERalpha content is regulated by estrogen. J Bone Miner Res 21: 1297-1306.
    • (2006) J Bone Miner Res , vol.21 , pp. 1297-1306
    • Zaman, G.1    Jessop, H.L.2    Muzylak, M.3    De Souza, R.L.4    Pitsillides, A.A.5
  • 51
    • 84872477285 scopus 로고    scopus 로고
    • Estrogen receptor-alpha is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2
    • Windahl SH, Saxon L, Borjesson AE, Lagerquist MK, Frenkel B, et al. (2013) Estrogen receptor-alpha is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2. J Bone Miner Res 28: 291-301.
    • (2013) J Bone Miner Res , vol.28 , pp. 291-301
    • Windahl, S.H.1    Saxon, L.2    Borjesson, A.E.3    Lagerquist, M.K.4    Frenkel, B.5


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