Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition

Journal of Bone and Mineral Research

Volumn 27, Issue 8, 2012, Pages 1784-1793

  Sugiyama, Toshihiro ^a,b   Meakin, Lee B ^a   Browne, William J ^a   Galea, Gabriel L ^a   Price, Joanna S ^a   Lanyon, Lance E ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

BONE LOADING; LAZY ZONE; MECHANOSTAT; MINIMUM EFFECTIVE STRAIN; STRAIN RELATED ADAPTATION

Indexed keywords

ADAPTIVE BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BIOMECHANICS; BONE; BONE DENSITY; BONE MASS; BONE STRENGTH; BONE STRESS; BONE STRUCTURE; CONTROLLED STUDY; CORTICAL BONE; DYNAMICS; FEMALE; LAMELLAR BODY; LOAD CARRYING CAPACITY; MECHANICAL LOADING; MICRO-COMPUTED TOMOGRAPHY; MOUSE; MULTIPLE REGRESSION; NEURECTOMY; NONHUMAN; REST; SCIATIC NERVE;

ADAPTATION, PHYSIOLOGICAL; AGING; ANIMALS; BIOMECHANICS; FEMALE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MUSCLES; REGRESSION ANALYSIS; SCIATIC NERVE; STRESS, MECHANICAL; TIBIA; WEIGHT-BEARING; X-RAY MICROTOMOGRAPHY;

EID: 84864139453     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1599     Document Type: Article

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