Nanostructured self-assembling peptides as a defined extracellular matrix for long-term functional maintenance of primary hepatocytes in a bioartificial liver modular device

International Journal of Nanomedicine

Volumn 8, Issue , 2013, Pages 1525-1539

  Giri, Shibashish ^a   Braumann, Ulf Dietrich ^a   Giri, Priya ^a   Acikgöz, Ali ^a,b   Scheibe, Patrick ^a,c   Nieber, Karen ^a   Bader, Augustinus ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b Klinikum St Georg   (Germany)

^c Translational Centre for Regenerative Medicine (TRM Leipzig)   (Germany)

Author keywords

3D visualization; Bioreactor; FDA guidelines; Hepatotoxicity; Image analysis; Primary hepatocytes

Indexed keywords

ALBUMIN; CYTOKINE; GLUTATHIONE TRANSFERASE; GROWTH FACTOR; LACTATE DEHYDROGENASE; NANOMATERIAL; PEPTIDE; UREA;

ALGORITHM; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; ARTIFICIAL LIVER; BIOPHYSICS; CELL MEMBRANE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FOOD AND DRUG ADMINISTRATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER CELL DAMAGE; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; MEDICAL DEVICE; NONHUMAN; PRACTICE GUIDELINE; PREDICTION; PROTEIN SECRETION; RAT; SENSITIVITY AND SPECIFICITY; STEADY STATE;

3D VISUALIZATION; BIOREACTOR; FDA GUIDELINES; HEPATOTOXICITY; IMAGE ANALYSIS; PRIMARY HEPATOCYTES;

ALBUMINS; ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL GROWTH PROCESSES; CELL MEMBRANE; CELLULAR MICROENVIRONMENT; CYTOCHROME P-450 CYP3A; EXTRACELLULAR MATRIX; HEPATOCYTES; LIVER, ARTIFICIAL; MALE; MITOCHONDRIA; MODELS, BIOLOGICAL; NANOSTRUCTURES; NANOTECHNOLOGY; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; TISSUE SCAFFOLDS; UREA;

ANIMALIA;

EID: 84876498293     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S33589     Document Type: Article

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