Preclinical characterization of primary porcine hepatocytes in a clinically relevant flat membrane bioreactor

Biomaterials

Volumn 31, Issue 1, 2010, Pages 156-172

  Maringka, Michael ^b   Giri, Shibashish ^a   Bader, Augustinus ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b Diakoniekrankenhaus Henriettenstiftung ^*  (Germany)

Author keywords

Bioartificial liver; Bioreactor; Cell morphology; Hepatocyte; Oxygenation; Plasma

Indexed keywords

ALBUMIN SECRETION; BIOARTIFICIAL LIVER; BIOREACTOR DESIGN; BLOOD PLASMA; CELL MORPHOLOGY; CLINICAL SITUATIONS; CULTURE MEDIUM; DIRECT CONTACT; FLAT MEMBRANE; FOCUS POINTS; GENERATION TIME; GLUTAMIC-OXALOACETIC TRANSAMINASE; GLUTAMIC-PYRUVIC TRANSAMINASE; HEPATOCYTE; HEPATOCYTES; HIGH-DENSITY CULTURES; HUMAN PATIENTS; HUMAN PLASMAS; IN-VITRO; IN-VIVO; INTACT CELLS; LACTATE DEHYDROGENASE; LITTLE RESEARCH; LIVER FAILURE; LIVER-SPECIFIC FUNCTIONS; LONG TERM STABILITY; LONG-TERM CULTURE; NUTRIENT SUPPLY; PLASMA EXPOSURE; SERUM-FREE MEDIA; SERUM-FREE MEDIUM; UREA SYNTHESIS;

BIOCONVERSION; BIOREACTORS; BLOOD; CELL CULTURE; CELL MEMBRANES; DETOXIFICATION; GELATION; GELS; LIVER; MORPHOLOGY; OXYGEN SUPPLY; OXYGENATION; OXYGENATORS; PLASMA (HUMAN); PLASMAS; UREA;

PLASMA STABILITY;

ALANINE AMINOTRANSFERASE; ALBUMIN; AMMONIA; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOREACTOR DESIGN; CELL CULTURE MONITORING; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DETOXIFICATION; ENZYME ACTIVITY; ENZYME RELEASE; FEMALE; FLAT MEMBRANE BIOREACTOR; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; LIVER CELL; LIVER FUNCTION; LIVER STRUCTURE; LIVER SUPPORT; MALE; MEMBRANE STABILIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SWINE; UREA CYCLE;

ADULT; ANIMALS; BIOREACTORS; FEMALE; HEPATOCYTES; HUMANS; MALE; MEMBRANES, ARTIFICIAL; SWINE;

SUS;

EID: 70350553820     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.09.020     Document Type: Article

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