Slow and sustained release of active cytokines from self-assembling peptide scaffolds

Journal of Controlled Release

Volumn 145, Issue 3, 2010, Pages 231-239

  Gelain, Fabrizio ^a,d   Unsworth, Larry D ^b,c   Zhang, Shuguang ^d  

^a Center for Nanomedicine and Tissue Engineering   (Italy)

^b UNIVERSITY OF ALBERTA   (Canada)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Cytokines; Drug release; Neural stem cells; Self assembling peptides

Indexed keywords

3-D CELL CULTURE; C-TERMINUS; CELLULAR ACTIVITIES; CELLULAR MICROENVIRONMENT; CLINICAL APPLICATION; CYTOKINES; DIFFUSIVE MECHANISMS; DRUG RELEASE; INDUCED INTERACTION; MOLECULAR LEVELS; MOLECULAR RELEASE; NANOSTRUCTURED SYSTEMS; NEGATIVE CHARGE; NEURAL STEM CELL; PROTEIN MOBILITY; REGENERATIVE MEDICINE; SELF-ASSEMBLING PEPTIDES; SUSTAINED RELEASE; WOUND HEALING;

ANIMAL CELL CULTURE; BIOLOGICAL MATERIALS; CELL CULTURE; DRUG PRODUCTS; NANOFIBERS; PEPTIDES; SCAFFOLDS; SELF ASSEMBLY;

STEM CELLS;

CYTOKINE; MOLECULAR SCAFFOLD; PEPTIDE DERIVATIVE; RADA16 DGE PEPTIDE; RADA16 I PEPTIDE; RADA16 PFS PEPTIDE; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR; RECOMBINANT BRAIN DERIVED NEUROTROPHIC FACTOR; RECOMBINANT VASCULOTROPIN; UNCLASSIFIED DRUG; VASCULOTROPIN 121; DELAYED RELEASE FORMULATION; FIBROBLAST GROWTH FACTOR; PEPTIDE;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL ASSAY; CELL CULTURE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NERVE REGENERATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; REGENERATIVE MEDICINE; SLOW DRUG RELEASE; SUSTAINED DRUG RELEASE; WOUND HEALING; ADULT STEM CELL; AMINO ACID SEQUENCE; ANIMAL; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DELAYED RELEASE FORMULATION; DIFFUSION; HUMAN; MOLECULAR GENETICS; TISSUE SCAFFOLD;

ADULT STEM CELLS; AMINO ACID SEQUENCE; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; DELAYED-ACTION PREPARATIONS; DIFFUSION; FIBROBLAST GROWTH FACTORS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; TISSUE SCAFFOLDS;

EID: 77954315817     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.04.026     Document Type: Article

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