1,25-(OH)2D3 down-regulates expression of Phex, a marker of the mature osteoblast

Endocrinology

Volumn 140, Issue 3, 1999, Pages 1192-1199

  Ecarot, Brigitte ^a   Desbarats, Marguerite ^a  

^a SHRINERS HOSPITAL FOR CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CALCITRIOL;

ANIMAL CELL; ARTICLE; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE DELETION; GENE EXPRESSION REGULATION; HYPOPHOSPHATEMIA; MEMBRANE BINDING; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION;

EID: 0032963140     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.3.6593     Document Type: Article

References (58)

1. 1. Rasmussen H, Tenenhouse HS 1989 Hypophosphatemias. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The Metabolic Basis of Inherited Diseases. McGraw-Hill Information Services, New York, pp 2581-2604
2. 2. Eicher EM, Southard JL, Scriver CR, Glorieux FH 1976 Hypophosphatemia: a mouse model for human familial hypophosphataemic (vitamin D-resistant) rickets. Proc Natl Acad Sci USA 73:4667-4671
3. 3. Tenenhouse HS, Scriver CR, McInnes RR, Glorieux FH 1978 Renal handling of phosphate in vivo and in vitro by the X-linked hypophosphatemic male mouse: evidence for a defect in the brush border membrane. Kidney Int 14:236-244
4. +-phosphate cotransport in murine X-linked hypophosphatemic rickets: molecular characterization. J Clin Invest 93:671-676
5. 5. Meyer Jr RA, Meyer MH, Gray RW 1989 Parabiosis suggests a humoral factor is involved in X-linked hypophosphatemia in mice. J Bone Miner Res 4:493-500
6. 6. Nesbitt T, Coffman TM, Griffiths R, Drezner MK 1992 Cross-transplantation of kidneys in normal and Hyp mice: evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defect. J Clin Invest 89:1453-1459
7. 7. Glorieux FH, Marie PJ, Pettifor J, Delvin EE 1980 Bone response to phosphate salts, ergocalciferol and calcitriol in hypophosphatemic vitamin D-resistant rickets. N Engl J Med 303:1023-1031
8. 8. Harrell RM, Lyles KW, Harrelson JM, Friedman NE, Drezner MK 1985 Healing of bone disease in X-linked hypophosphatemic rickets/osteomalacia. Induction and maintenance with phosphorus and calcitriol. J Clin Invest 75:1858-1868
9. 9. Marie PJ, Travers R, Glorieux FH 1981 Healing of rickets with phosphate supplementation in the hypophosphatemic male mouse. J Clin Invest 67:911-914
10. 3 in the young X-linked hypophosphatemic male mouse. Endocrinology 111:904-911
11. 11. Frost HM 1958 Some observations on bone mineral in a case of vitamin D resistant rickets. Henry Ford Med Bull 6:300-310
12. 12. Marie PJ, Glorieux FH 1983 Relation between hypomineralized periosteocytic lesions and bone mineralization in vitamin-D resistant rickets. Calcif Tissue Int 35:443-448
13. 13. Ecarot-Charrier B, Glorieux FH, Travers R, Desbarats M, Bouchard F, Hinek A 1988 Defective bone formation by transplanted Hyp mouse bone cells into normal mice. Endocrinology 123:768-773
14. 14. Ecarot B, Glorieux FH, Desbarats M, Travers R, Labelle L 1992 Defective bone formation by Hyp mouse bone cells transplanted into normal mice: evidence in favor of an intrinsic osteoblast defect. J Bone Miner Res 7:215-220
15. 15. Ecarot B, Glorieux FH, Desbarats M, Travers R, Labelle L 1992 Effect of dietary phosphate deprivation and supplementation of recipient mice on bone formation by transplanted cells from normal and X-linked hypophosphatemic mice. J Bone Miner Res 7:523-530
16. 3 treatment on bone formation by transplanted cells from normal and X-linked hypophosphatemic mice. J Bone Miner Res 10:424-431
17. 17. The HYP Consortium 1995 A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 11:130-136
18. 18. Rowe PSN, Oudet CL, Francis F, Sinding C, Pannetier S, Econs MJ, Strom TM, Meltinger T, Garabedian M, David A, Macher MA, Questiaux E, Popowska E, Pronicka E, Read AP, Mokkrzycki A, Glorieux FH, Drezner MK, Hanauer A, Lehrach H, Goulding JN, O'Riordan LH 1997 Distribution of mutations in the PEX gene in families with X-linked hypophosphatemic rickets (HYP). Hum Mol Genet 6:539-549
19. 19. Holm IA, Huang X, Kunkel LM 1997 Mutational analysis of the PEX gene in patients with X-linked hypophosphatemic rickets. Am J Hum Genet 60:790-797
20. 20. Strom TM, Francis F, Lorenz B, Boddrich A, Econs MJ, Lehrach H, Meitenger T 1997 Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia. Hum Mol Genet 6:165-171
21. 21. Beck L, Soumounou Y, Martel J, Krishnamurthy G, Gauthier C, Goodyer CG, Tenenhouse HS 1997 Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice. J Clin Invest 99:1200-1209
22. 22. Turner AJ, Tanzawa K 1997 Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX. FASEB J 11:355-364
23. 23. Roques BP, Noble F, Dauge V, Fournie-Zaluski MC, Beaumont A 1993 Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology. Fharmacol Rev 45:87-146
24. 24. Xu D, Emoto N, Giaid A, Slaughter C, Kaw S, deWit D, Yanagisawa M 1994 ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1. Cell 78:473-485
25. 25. Emoto N, Yanagisawa M 1995 Endothelin-converting enzyme-2 is a membrane bound, phosphoramidon-sensitive, metalloprotease with acidic pH optimum. J Biol Chem 270:15262-15268
26. 26. Du L, Desbarats M, Viel J, Glorieux FH, Cawthorn C, Ecarot B 1996 cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence of expression in bone. Genomics 36:22-28
27. 27. Grieff M, Mumm S, Waeltz P, Mazzarella R, Whyte MP, Thakker RV, Schlessinger D 1997 Expression and cloning of the human X-linked hypophosphatemia gene cDNA. Biochem Biophys Res Commun 231:635-639
28. 28. Ecarot-Charrier B, Glorieux FH, van der Rest M, Pereira G 1983 Osleoblasts isolated from mouse calvaria initiate matrix mineralization in culture. J Cell Biol 96:639-643
29. 29. Smith JH, Denhardt DT 1987 Molecular cloning of a tumor promoter-inducible mRNA found in JB6 mouse epidermal cells: induction is stable at high, but not at low, cell densities. J Cell Biochem 34:13-22
30. 30. Sudo H, Kodama H, Amagai U, Yamamoto S, Kasai S 1983 In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 96:191-198
31. 31. Quarles LD, Yohay AY, Lever LW, Caton R, Wenstrup RJ 1992 Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development. J Bone Miner Res 7:683-692
32. 32. Manduca P, Palermo C, Caruso C, Brizzolara A, Sanguineti C, Filanti C, Zicca A 1997 Rat tibial osteoblasts III: propagation in vitro is accompanied by enhancement of osteoblast phenotype. Bone 21:31-39
33. 33. Lian JB, Shalhoub V, Aslam F, Frenkel B, Green J, Hamrah M, Stein GS, Stein JL 1997 Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression. Endocrinology 138:2117-2127
34. 34. Zhang R, Ducy P, Karsenty G 1997 1,25-dihydroxyvitamin D3 inhibits osteocalcin expression in mouse through an indirect mechanism. J Biol Chem 272:110-116
35. 35. Guo R, Quarles LD 1997 Cloning and sequencing of human PEX from a cDNA library: evidence for its developmental stage-specific regulation in osteoblasts. J Bone Miner Res 12:1009-1017
36. 36. Ecarot-Charrier B, Shepard N, Charette G, Grynpas M, Glorieux FH 1988 Mineralization in osteoblast cultures: a light and electron microscopic study. Bone 9:147-154
37. 37. Lee KL, Aubin JE, Heersche JN 1992 beta-Glycerophosphate-induced mineralization of osteoid does not alter expression of extracellular matrix components in fetal rat calvarial cell cultures. J Bone Miner Res 7:1211-1219
38. 38. Gerstenfeld LC, Chipman SD, Glowacki J, Lian JB 1987 Expression of differentiated function by mineralizing cultures of chicken osteoblasts. Dev Biol 122:49-60
39. 39. Aronow MA, Gerstenfeld LC, Owen TA, Tassinari MS, Stein GS, Lian JB 1990 Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvarial cells. J Cell Physiol 143:213-221
40. 40. Weinstein RS, Underwood JL, Hutson MS, DeLuca HF 1984 Bone histomorphometry in vitamin D-deficient rats infused with calcium and phosphorus. Am J Physiol 246:E499-E505
41. 41. Meunier PJ, Edouard C, Ailot M, Lejeune E, Alexandre C, Leroy G 1979 Effect of 1,25-dihydroxyvitamin D on bone mineralization, In: MacIntyre I, Szelke M (eds) Molecular Endocrinology. Amsterdam Elsevier/North Holland, pp 283-292
42. 42. Chen TL, Hauschka PV, Cabrales S, Feldman D 1986 The effects of 1,25-dihydroxyvitamin D3 and dexamethasone on rat osteoblast-like primary cell cultures: receptor occupancy and functional expression patterns for three different bioresponses. Endocrinology 118:250-259
43. 43. Franceschi RT, Romano PR, Park KY 1988 Regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D3 in human osteosarcoma cells. J Biol Chem 263:18938-18945
44. 44. Owen TA, Aronow MA, Barone LM, Bettencourt B, Stein GS, Lian JB 1990 Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal level of gene expression, duration of exposure, and bone matrix competency in normal rat osteoblast cultures. Endocrinology 128:1496-1504
45. 45. Kurihara N, Ishizuka S, Kiyoki M, Haketa Y, Ikeda K, Kumegawa M 1986 Effects of 1,25-dihydroxyvitamin D3 on osteoblastic MC3T3-E1 cells. Endocrinology 118:940-947
46. 46. Beresford JN, Gallagher JA, Russell RG 1986 1,25-Dihydroxyvitamin D3 and human bone-derived cells in vitro: effects on alkaline phosphatase, type I collagen and proliferation. Endocrinology 119:1776-1785
47. 47. Manolagas SC, Burton DW, Deftos LJ 1981 1,25-Dihydroxyvitamin D3 stimulates the alkaline phosphatase activity of osteoblast-like cells. J Biol Chem 256:7115-7117
48. 48. Majeska RJ, Rodan GA 1982 The effect of 1,25(OH)2D3 on alkaline phosphatase in osteoblastic osteosarcoma cells. J Biol Chem 257:3362-3365
49. 49. Spiess YH, Price PA, Deftos JL, Manolagas SC 1986 Phenotype-associated changes in the effects of 1,25-dihydroxyvitamin D3 on alkaline phosphatase and bone GLA-protein of rat osteoblastic cells. Endocrinology 118:1340-1346
50. 50. Price PA, Baukol SA 1980 1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells. J Biol Chem 255:11660-11663
51. 3 on collagen type I, osteopontin, and osteocalcin gene expression in chicken osteoblats. J Biol Chem 269:1183-1190
52. 52. Prince CW, Butler WT 1987 1,25-Dihydroxyvitamin D3 regulates the biosynthesis of osteopontin, a bone-derived cell attachment protein, in clonal osteoblast-like osteosarcoma cells. Coll Relat Res 7:305-313
53. 3-induced inhibition of bone nodule formation in long-term cultures of fetal rat calvaria cells. Endocrinology 132:61-66
54. 3 of in vitro mineralization induced by osteoblast-like MC3T3-E1 cells. Bone 12:27-32
55. 55. Koshihara Y, Hoshi K, Ishibashi H, Shiraki M 1996 Vitamin K2 promotes 1alpha,25(OH)2D3-induced mineralization in human periosteal osteoblasts. Calcif Tissue Int 59:466-473
56. 3 on bone matrix and mineral appositional rates in the mouse. Metabolism 34:777-783
57. 57. Wronski TJ, Halloran BP, Bikle DD, Globus RK, Morey-Holton ER 1986 Chronic administration of 1,25-dihydroxyvitamin D3: increased bone but impaired mineralization. Endocrinology 119:2580-2585
58. 3 in long bones. Calcif Tissue Int 28:79-86