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Volumn 392, Issue 2, 2010, Pages 124-128

Repressive BMP2 gene regulatory elements near the BMP2 promoter

Author keywords

Bone morphogenetic protein 2 (BMP2); Enhancer; Fibroblast growth factor (FGF2); Gene regulation; Osteoblast; Transgenic mice

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; FIBROBLAST GROWTH FACTOR 2;

EID: 75749108893     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.12.157     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 12344291865 scopus 로고    scopus 로고
    • Bone morphogenetic proteins
    • Chen D., Zhao M., and Mundy G.R. Bone morphogenetic proteins. Growth Factors 22 (2004) 233-241
    • (2004) Growth Factors , vol.22 , pp. 233-241
    • Chen, D.1    Zhao, M.2    Mundy, G.R.3
  • 2
    • 0025672641 scopus 로고
    • Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone
    • Celeste A.J., Iannazi J.A., Taylor R.C., Hewick R.M., Rosen V., Wang E.A., and Wozney J.M. Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc. Natl. Acad. Sci. USA 87 (1990) 9843-9847
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Iannazi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5    Wang, E.A.6    Wozney, J.M.7
  • 3
    • 34250019537 scopus 로고
    • Bone: formation by autoinduction
    • Urist M. Bone: formation by autoinduction. Science 150 (1965) 893-899
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.1
  • 5
    • 0024761677 scopus 로고
    • Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-β-like genes coordinately regulate aspects of embryonic development
    • Lyons K., Pelton R., and Hogan B. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-β-like genes coordinately regulate aspects of embryonic development. Genes Dev. 3 (1989) 1657-1668
    • (1989) Genes Dev. , vol.3 , pp. 1657-1668
    • Lyons, K.1    Pelton, R.2    Hogan, B.3
  • 6
    • 0024991197 scopus 로고
    • Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)
    • Lyons K.M., Pelton R.W., and Hogan B.L.M. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A). Development 109 (1990) 833-844
    • (1990) Development , vol.109 , pp. 833-844
    • Lyons, K.M.1    Pelton, R.W.2    Hogan, B.L.M.3
  • 7
    • 0037376627 scopus 로고    scopus 로고
    • Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation
    • Gerstenfeld L.C., Cullinane D.M., Barnes G.L., Graves D.T., and Einhorn T.A. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J. Cell. Biochem. 88 (2003) 873-884
    • (2003) J. Cell. Biochem. , vol.88 , pp. 873-884
    • Gerstenfeld, L.C.1    Cullinane, D.M.2    Barnes, G.L.3    Graves, D.T.4    Einhorn, T.A.5
  • 9
    • 0029850112 scopus 로고    scopus 로고
    • Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
    • Zhang H., and Bradley A. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122 (1996) 2977-2986
    • (1996) Development , vol.122 , pp. 2977-2986
    • Zhang, H.1    Bradley, A.2
  • 10
    • 0034999789 scopus 로고    scopus 로고
    • Identification of new bone morphogenetic protein-related members in invertebrates
    • Lelong C., Mathieu M., and Favrel P. Identification of new bone morphogenetic protein-related members in invertebrates. Biochimie 83 (2001) 423-426
    • (2001) Biochimie , vol.83 , pp. 423-426
    • Lelong, C.1    Mathieu, M.2    Favrel, P.3
  • 11
    • 0027161383 scopus 로고
    • Drosophila transforming growth factor b superfamily proteins induce endochondral bone formation in mammals
    • Sampath T.K., Rashka K.E., Doctor J.S., Tucker R.F., and Hoffmann F.M. Drosophila transforming growth factor b superfamily proteins induce endochondral bone formation in mammals. Proc. Natl. Acad. Sci. USA 90 (1993) 6004-6008
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6004-6008
    • Sampath, T.K.1    Rashka, K.E.2    Doctor, J.S.3    Tucker, R.F.4    Hoffmann, F.M.5
  • 12
    • 0029034915 scopus 로고
    • Upside-down ideas vindicated
    • Hogan B. Upside-down ideas vindicated. Nature 376 (1995) 210-211
    • (1995) Nature , vol.376 , pp. 210-211
    • Hogan, B.1
  • 13
    • 0027081776 scopus 로고
    • Bone morphogenetic proteins-2 and 4 are involved in the retinoic acid-induced differentiation of embryonal carcinoma cells
    • Rogers M.B., Rosen V., Wozney J.M., and Gudas L.J. Bone morphogenetic proteins-2 and 4 are involved in the retinoic acid-induced differentiation of embryonal carcinoma cells. Mol. Biol. Cell 3 (1992) 189-196
    • (1992) Mol. Biol. Cell , vol.3 , pp. 189-196
    • Rogers, M.B.1    Rosen, V.2    Wozney, J.M.3    Gudas, L.J.4
  • 14
    • 0030060642 scopus 로고    scopus 로고
    • Receptor-selective retinoids implicate RAR alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells
    • Rogers M. Receptor-selective retinoids implicate RAR alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells. Cell Growth Differ. 7 (1996) 115-122
    • (1996) Cell Growth Differ. , vol.7 , pp. 115-122
    • Rogers, M.1
  • 15
    • 0034601692 scopus 로고    scopus 로고
    • Regulation of the promoters for the human bone morphogenetic protein 2 and 4 genes
    • Helvering L.M., Sharp R.L., Ou X., and Geiser A.G. Regulation of the promoters for the human bone morphogenetic protein 2 and 4 genes. Gene 256 (2000) 123-138
    • (2000) Gene , vol.256 , pp. 123-138
    • Helvering, L.M.1    Sharp, R.L.2    Ou, X.3    Geiser, A.G.4
  • 16
    • 0028137737 scopus 로고
    • Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb
    • Francis P.H., Richardson M.K., Brickell P.M., and Tickle C. Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development 120 (1994) 209-218
    • (1994) Development , vol.120 , pp. 209-218
    • Francis, P.H.1    Richardson, M.K.2    Brickell, P.M.3    Tickle, C.4
  • 18
    • 1942533514 scopus 로고    scopus 로고
    • Pre-B cell leukemia transcription factor (PBX) proteins are important mediators for retinoic acid-dependent endodermal and neuronal differentiation of mouse embryonal carcinoma P19 cells
    • Qin P., Haberbusch J.M., Zhang Z., Soprano K.J., and Soprano D.R. Pre-B cell leukemia transcription factor (PBX) proteins are important mediators for retinoic acid-dependent endodermal and neuronal differentiation of mouse embryonal carcinoma P19 cells. J. Biol. Chem. 279 (2004) 16263-16271
    • (2004) J. Biol. Chem. , vol.279 , pp. 16263-16271
    • Qin, P.1    Haberbusch, J.M.2    Zhang, Z.3    Soprano, K.J.4    Soprano, D.R.5
  • 19
    • 43449124709 scopus 로고    scopus 로고
    • Mycoplasma infection transforms normal lung cells and induces bone morphogenetic protein 2 expression by post-transcriptional mechanisms
    • Jiang S., Zhang S., Langenfeld J., Lo S.C., and Rogers M.B. Mycoplasma infection transforms normal lung cells and induces bone morphogenetic protein 2 expression by post-transcriptional mechanisms. J. Cell. Biochem. 104 (2007) 580-594
    • (2007) J. Cell. Biochem. , vol.104 , pp. 580-594
    • Jiang, S.1    Zhang, S.2    Langenfeld, J.3    Lo, S.C.4    Rogers, M.B.5
  • 23
    • 0043237419 scopus 로고    scopus 로고
    • NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro
    • Feng J.Q., Xing L., Zhang J.H., Zhao M., Horn D., Chan J., Boyce B.F., Harris S.E., Mundy G.R., and Chen D. NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro. J. Biol. Chem. 278 (2003) 29130-29135
    • (2003) J. Biol. Chem. , vol.278 , pp. 29130-29135
    • Feng, J.Q.1    Xing, L.2    Zhang, J.H.3    Zhao, M.4    Horn, D.5    Chan, J.6    Boyce, B.F.7    Harris, S.E.8    Mundy, G.R.9    Chen, D.10
  • 24
    • 0043136513 scopus 로고    scopus 로고
    • Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes
    • Fukui N., Zhu Y., Maloney W.J., Clohisy J., and Sandell L.J. Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes. J. Bone Joint Surg. Am. 85-A Suppl. 3 (2003) 59-66
    • (2003) J. Bone Joint Surg. Am. , vol.85 -A , Issue.SUPPL. 3 , pp. 59-66
    • Fukui, N.1    Zhu, Y.2    Maloney, W.J.3    Clohisy, J.4    Sandell, L.J.5
  • 25
    • 0142072322 scopus 로고    scopus 로고
    • Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis
    • Lories R.J., Derese I., Ceuppens J.L., and Luyten F.P. Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. Arthritis Rheum. 48 (2003) 2807-2818
    • (2003) Arthritis Rheum. , vol.48 , pp. 2807-2818
    • Lories, R.J.1    Derese, I.2    Ceuppens, J.L.3    Luyten, F.P.4
  • 27
    • 14144251710 scopus 로고    scopus 로고
    • Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential
    • Fakhry A., Ratisoontorn C., Vedhachalam C., Salhab I., Koyama E., Leboy P., Pacifici M., Kirschner R.E., and Nah H.D. Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential. Bone 36 (2005) 254-266
    • (2005) Bone , vol.36 , pp. 254-266
    • Fakhry, A.1    Ratisoontorn, C.2    Vedhachalam, C.3    Salhab, I.4    Koyama, E.5    Leboy, P.6    Pacifici, M.7    Kirschner, R.E.8    Nah, H.D.9
  • 30
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonists, and the skeleton
    • Canalis E., Economides A.N., and Gazzerro E. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr. Rev. 24 (2003) 218-235
    • (2003) Endocr. Rev. , vol.24 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 31
    • 21344437987 scopus 로고    scopus 로고
    • BMP antagonists: their roles in development and involvement in pathophysiology
    • Yanagita M. BMP antagonists: their roles in development and involvement in pathophysiology. Cytokine Growth Factor Rev. 16 (2005) 309-317
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 309-317
    • Yanagita, M.1
  • 32
    • 33645500812 scopus 로고    scopus 로고
    • Turning off Smads: identification of a Smad phosphatase
    • Hill C.S. Turning off Smads: identification of a Smad phosphatase. Dev. Cell 10 (2006) 412-413
    • (2006) Dev. Cell , vol.10 , pp. 412-413
    • Hill, C.S.1
  • 33
  • 35
    • 33748754439 scopus 로고    scopus 로고
    • Pro-inflammatory cytokine tumor necrosis factor-alpha induces bone morphogenetic protein-2 in chondrocytes via mRNA stabilization and transcriptional up-regulation
    • Fukui N., Ikeda Y., Ohnuki T., Hikita A., Tanaka S., Yamane S., Suzuki R., Sandell L.J., and Ochi T. Pro-inflammatory cytokine tumor necrosis factor-alpha induces bone morphogenetic protein-2 in chondrocytes via mRNA stabilization and transcriptional up-regulation. J. Biol. Chem. 281 (2006) 27229-27241
    • (2006) J. Biol. Chem. , vol.281 , pp. 27229-27241
    • Fukui, N.1    Ikeda, Y.2    Ohnuki, T.3    Hikita, A.4    Tanaka, S.5    Yamane, S.6    Suzuki, R.7    Sandell, L.J.8    Ochi, T.9
  • 37
    • 33947621669 scopus 로고    scopus 로고
    • Modulation of bone morphogenetic protein (BMP) 2 gene expression by Sp1 transcription factors
    • Xu J., and Rogers M.B. Modulation of bone morphogenetic protein (BMP) 2 gene expression by Sp1 transcription factors. Gene 392 (2007) 221-229
    • (2007) Gene , vol.392 , pp. 221-229
    • Xu, J.1    Rogers, M.B.2
  • 38
    • 0035154902 scopus 로고    scopus 로고
    • Regulation of gene expression by GC-rich DNA cis-elements
    • Hapgood J.P., Riedemann J., and Scherer S.D. Regulation of gene expression by GC-rich DNA cis-elements. Cell Biol. Int. 25 (2001) 17-31
    • (2001) Cell Biol. Int. , vol.25 , pp. 17-31
    • Hapgood, J.P.1    Riedemann, J.2    Scherer, S.D.3
  • 40
    • 0033555544 scopus 로고    scopus 로고
    • Transcriptional regulation of the Bmp2 gene: retinoic acid induction in F9 embryonal carcinoma cells and Saccharomyces cerevisiae
    • Heller L.C., Li Y., Abrams K.A., and Rogers M.B. Transcriptional regulation of the Bmp2 gene: retinoic acid induction in F9 embryonal carcinoma cells and Saccharomyces cerevisiae. J. Biol. Chem. 274 (1999) 1394-1400
    • (1999) J. Biol. Chem. , vol.274 , pp. 1394-1400
    • Heller, L.C.1    Li, Y.2    Abrams, K.A.3    Rogers, M.B.4
  • 41
    • 0031029768 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5′ non-coding region arising from a distal promoter
    • Feng J.Q., Chen D., Ghosh-Choudhury N., Esparza J., Mundy G.R., and Harris S.E. Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5′ non-coding region arising from a distal promoter. Biochim. Biophys. Acta 1350 (1997) 47-52
    • (1997) Biochim. Biophys. Acta , vol.1350 , pp. 47-52
    • Feng, J.Q.1    Chen, D.2    Ghosh-Choudhury, N.3    Esparza, J.4    Mundy, G.R.5    Harris, S.E.6
  • 42
    • 34147205885 scopus 로고    scopus 로고
    • Bmp2 transcription in osteoblast progenitors is regulated by a distant 3′ enhancer located 156.3 kilobases from the promoter
    • Chandler R.L., Chandler K.J., McFarland K.A., and Mortlock D.P. Bmp2 transcription in osteoblast progenitors is regulated by a distant 3′ enhancer located 156.3 kilobases from the promoter. Mol. Cell. Biol. 27 (2007) 2934-2951
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 2934-2951
    • Chandler, R.L.1    Chandler, K.J.2    McFarland, K.A.3    Mortlock, D.P.4
  • 43
    • 0037380723 scopus 로고    scopus 로고
    • Comparative genomics: genome-wide analysis in metazoan eukaryotes
    • Ureta-Vidal A., Ettwiller L., and Birney E. Comparative genomics: genome-wide analysis in metazoan eukaryotes. Nat. Rev. Genet. 4 (2003) 251-262
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 251-262
    • Ureta-Vidal, A.1    Ettwiller, L.2    Birney, E.3
  • 44
    • 0345293157 scopus 로고    scopus 로고
    • Gradients and thresholds: BMP response gradients unveiled in Drosophila embryos
    • Raftery L.A., and Sutherland D.J. Gradients and thresholds: BMP response gradients unveiled in Drosophila embryos. Trends Genet. 19 (2003) 701-708
    • (2003) Trends Genet. , vol.19 , pp. 701-708
    • Raftery, L.A.1    Sutherland, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.