Aberrant schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy

Neuron

Volumn 77, Issue 5, 2013, Pages 886-898

  Viader, Andreu ^a   Sasaki, Yo ^a   Kim, Sungsu ^a   Strickland, Amy ^a   Workman, Cayce S ^a   Yang, Kui ^a   Gross, Richard W ^a   Milbrandt, Jeffrey ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; HEME REGULATED INHIBITOR KINASE; LIPID; MYELIN; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; ANILINE DERIVATIVE; CARNITINE; DRUG DERIVATIVE; EIF2ALPHA KINASE, MOUSE; FATTY ACID; FLUO 4; FLUORESCENT DYE; PROTEIN SERINE THREONINE KINASE; XANTHENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CELL ACTIVATION; CELL DISRUPTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; FEMALE; INTEGRATED STRESS RESPONSE; LIPID COMPOSITION; LIPID METABOLISM; LIPID STORAGE; MALE; MOUSE; NERVE FIBER DEGENERATION; NONHUMAN; PATHOLOGY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN DEPLETION; SCHWANN CELL; STRESS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; MICROARRAY ANALYSIS; MITOCHONDRIAL ENCEPHALOMYOPATHY; MOUSE MUTANT; NERVE DEGENERATION; NERVE FIBER; PHYSIOLOGY; SPINAL GANGLION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANILINE COMPOUNDS; ANIMALS; AXONS; BLOTTING, WESTERN; CARNITINE; CELLS, CULTURED; FATTY ACIDS; FLUORESCENT DYES; GANGLIA, SPINAL; LIPID METABOLISM; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROARRAY ANALYSIS; MITOCHONDRIAL ENCEPHALOMYOPATHIES; NERVE DEGENERATION; PERIPHERAL NERVOUS SYSTEM DISEASES; PROTEIN-SERINE-THREONINE KINASES; SCHWANN CELLS; XANTHENES;

MLCS; MLOWN;

EID: 84876428871     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2013.01.012     Document Type: Article

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