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Volumn 33, Issue 1, 2013, Pages 190-199

Activation of liver X receptors suppresses inflammatory gene expressions and transcriptional corepressor clearance in rheumatoid arthritis fibroblast like synoviocytes

Author keywords

Fibroblast like synoviocyte; GW3965; Liver X receptors; Rheumatoid arthritis; Transcriptional corepressor

Indexed keywords

3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; CASPASE 3; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIVER X RECEPTOR; AUTACOID; ORPHAN NUCLEAR RECEPTOR; REPRESSOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84876424490     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-012-9799-4     Document Type: Article
Times cited : (12)

References (35)
  • 1
    • 0034518420 scopus 로고    scopus 로고
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
    • Repa JJ, Mangelsdorf DJ. The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol. 2000;16:459-81.
    • (2000) Annu Rev Cell Dev Biol. , vol.16 , pp. 459-481
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 3
    • 54049115560 scopus 로고    scopus 로고
    • Activation of Liver X Receptors promotes neuroprotection and reduces brain inflammation in experimental stroke
    • Morales JR, Ballesteros I, Deniz JM, Hurtado O, Vivancos J, Nombela F, et al. Activation of Liver X Receptors promotes neuroprotection and reduces brain inflammation in experimental stroke. Circulation. 2008;118:1450-9.
    • (2008) Circulation. , vol.118 , pp. 1450-1459
    • Morales, J.R.1    Ballesteros, I.2    Deniz, J.M.3    Hurtado, O.4    Vivancos, J.5    Nombela, F.6
  • 4
    • 15944371262 scopus 로고    scopus 로고
    • Liver X receptor agonists inhibit tissue factor expression in macrophages
    • Terasaka N, Hiroshima A, Ariga A, Honzumi S, Koieyama T, Inaba T, et al. Liver X receptor agonists inhibit tissue factor expression in macrophages. FEBS J. 2005;272:1546-56.
    • (2005) FEBS J. , vol.272 , pp. 1546-1556
    • Terasaka, N.1    Hiroshima, A.2    Ariga, A.3    Honzumi, S.4    Koieyama, T.5    Inaba, T.6
  • 5
    • 67349112811 scopus 로고    scopus 로고
    • The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro
    • Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, et al. The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro. Diabetologia. 2009;52:1352-62.
    • (2009) Diabetologia. , vol.52 , pp. 1352-1362
    • Scholz, H.1    Lund, T.2    Dahle, M.K.3    Collins, J.L.4    Korsgren, O.5    Wang, J.E.6
  • 6
    • 0038193542 scopus 로고    scopus 로고
    • Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
    • Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J Biol Chem. 2003;278:10443-9.
    • (2003) J Biol Chem. , vol.278 , pp. 10443-10449
    • Castrillo, A.1    Joseph, S.B.2    Marathe, C.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 7
    • 33646785780 scopus 로고    scopus 로고
    • Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation
    • Wang YY, Dahle MK, Agren J, Myhre AE, Reinholt FP, Foster SJ, et al. Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation. Shock. 2006;25:141-6.
    • (2006) Shock. , vol.25 , pp. 141-146
    • Wang, Y.Y.1    Dahle, M.K.2    Agren, J.3    Myhre, A.E.4    Reinholt, F.P.5    Foster, S.J.6
  • 8
    • 33845970925 scopus 로고    scopus 로고
    • Parallel SUMOylationdependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma
    • Ghisletti S, Huang W, Ogawa S, et al. Parallel SUMOylationdependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell. 2007;25:57-70.
    • (2007) Mol Cell. , vol.25 , pp. 57-70
    • Ghisletti, S.1    Huang, W.2    Ogawa, S.3
  • 9
    • 63049122784 scopus 로고    scopus 로고
    • Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
    • Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, et al. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009;23:681-93.
    • (2009) Genes Dev. , vol.23 , pp. 681-693
    • Ghisletti, S.1    Huang, W.2    Jepsen, K.3    Benner, C.4    Hardiman, G.5    Rosenfeld, M.G.6
  • 10
    • 76749125430 scopus 로고    scopus 로고
    • GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response
    • Venteclef N, Jakobsson T, Ehrlund A, Damdimopoulos A, Mikkonen L, Ellis E, et al. GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Genes Dev. 2010;24:381-95.
    • (2010) Genes Dev. , vol.24 , pp. 381-395
    • Venteclef, N.1    Jakobsson, T.2    Ehrlund, A.3    Damdimopoulos, A.4    Mikkonen, L.5    Ellis, E.6
  • 11
    • 33144463109 scopus 로고    scopus 로고
    • Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis
    • Haringman JJ, Smeets TJ, Reinders-Blankert P, Tak PP. Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis. Ann Rheum Dis. 2006;65:294-300.
    • (2006) Ann Rheum Dis. , vol.65 , pp. 294-300
    • Haringman, J.J.1    Smeets, T.J.2    Reinders-Blankert, P.3    Tak, P.P.4
  • 12
    • 50849144863 scopus 로고    scopus 로고
    • Molecular aspects of rheumatoid arthritis: Chemokines in the joints of patients
    • Iwamoto T, Okamoto H, Toyama Y, Momohara S. Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients. FEBS J. 2008;275:4448-55.
    • (2008) FEBS J. , vol.275 , pp. 4448-4455
    • Iwamoto, T.1    Okamoto, H.2    Toyama, Y.3    Momohara, S.4
  • 13
    • 79955528848 scopus 로고    scopus 로고
    • Cell and cytokine imbalances in rheumatoid synovitis
    • Boissier MC. Cell and cytokine imbalances in rheumatoid synovitis. Joint Bone Spine. 2011;78:230-4.
    • (2011) Joint Bone Spine. , vol.78 , pp. 230-234
    • Boissier, M.C.1
  • 15
    • 79952481326 scopus 로고    scopus 로고
    • Liver X receptor agonist prevents the evolution of collagen-induced arthritis in mice
    • Park MC, Kwon YJ, Chung SJ, Park YB, Lee SK. Liver X receptor agonist prevents the evolution of collagen-induced arthritis in mice. Rheumatology. 2010;49:882-90.
    • (2010) Rheumatology. , vol.49 , pp. 882-890
    • Park, M.C.1    Kwon, Y.J.2    Chung, S.J.3    Park, Y.B.4    Lee, S.K.5
  • 17
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315-24.
    • (1988) Arthritis Rheum. , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3    McShane, D.J.4    Fries, J.F.5    Cooper, N.S.6
  • 18
    • 0037046543 scopus 로고    scopus 로고
    • Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines
    • Collins JL, Fivush AM, Watson MA, Galardi CM, Lewis MC, Moore LB, et al. Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines. J Med Chem. 2002;45:1963-6.
    • (2002) J Med Chem. , vol.45 , pp. 1963-1966
    • Collins, J.L.1    Fivush, A.M.2    Watson, M.A.3    Galardi, C.M.4    Lewis, M.C.5    Moore, L.B.6
  • 20
    • 34249682775 scopus 로고    scopus 로고
    • Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: Liver X receptor-mediated lipotoxicity in pancreatic beta-cells
    • Choe SS, Choi AH, Lee JW, Kim KH, Chung JJ, Park J, et al. Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells. Diabetes. 2007;56:1534-43.
    • (2007) Diabetes. , vol.56 , pp. 1534-1543
    • Choe, S.S.1    Choi, A.H.2    Lee, J.W.3    Kim, K.H.4    Chung, J.J.5    Park, J.6
  • 21
    • 57249094223 scopus 로고    scopus 로고
    • Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest
    • Meng ZX, Nie J, Ling JJ, Sun JX, Zhu YX, Gao L, et al. Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest. Diabetologia. 2009;52:125-35.
    • (2009) Diabetologia. , vol.52 , pp. 125-135
    • Meng, Z.X.1    Nie, J.2    Ling, J.J.3    Sun, J.X.4    Zhu, Y.X.5    Gao, L.6
  • 22
    • 80053421469 scopus 로고    scopus 로고
    • ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice
    • Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, et al. ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice. J Clin Invest. 2011;121:4138-49.
    • (2011) J Clin Invest. , vol.121 , pp. 4138-4149
    • Murphy, A.J.1    Akhtari, M.2    Tolani, S.3    Pagler, T.4    Bijl, N.5    Kuo, C.L.6
  • 23
    • 79955030449 scopus 로고    scopus 로고
    • Liver X receptors inhibit macrophage proliferation through downregulation of cyclins D1 and B1 and cyclindependent kinases 2 and 4
    • Pascual-García M, Carbó JM, León T, Matalonga J, Out R, Van Berkel T, et al. Liver X receptors inhibit macrophage proliferation through downregulation of cyclins D1 and B1 and cyclindependent kinases 2 and 4. J Immunol. 2011;186:4656-67.
    • (2011) J Immunol. , vol.186 , pp. 4656-4667
    • Pascual-García, M.1    Carbó, J.M.2    León, T.3    Matalonga, J.4    Out, R.5    Van Berkel, T.6
  • 24
    • 78650043469 scopus 로고    scopus 로고
    • Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity
    • Kim KH, Lee GY, Kim JI, Ham M, Won Lee J, Kim JB. Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity. J Lipid Res. 2010;51:3425-33.
    • (2010) J Lipid Res. , vol.51 , pp. 3425-3433
    • Kim, K.H.1    Lee, G.Y.2    Kim, J.I.3    Ham, M.4    Won Lee, J.5    Kim, J.B.6
  • 25
    • 77952242043 scopus 로고    scopus 로고
    • Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells
    • Pommier AJ, Alves G, Viennois E, Bernard S, Communal Y, Sion B, et al. Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells. Oncogene. 2010;29:2712-23.
    • (2010) Oncogene. , vol.29 , pp. 2712-2723
    • Pommier, A.J.1    Alves, G.2    Viennois, E.3    Bernard, S.4    Communal, Y.5    Sion, B.6
  • 26
    • 80053437599 scopus 로고    scopus 로고
    • Survival in the rheumatoid synovium
    • Wachsmann D, Sibilia J. Survival in the rheumatoid synovium. Joint Bone Spine. 2011;78:435-7.
    • (2011) Joint Bone Spine. , vol.78 , pp. 435-437
    • Wachsmann, D.1    Sibilia, J.2
  • 28
    • 0034669025 scopus 로고    scopus 로고
    • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
    • Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev. 2000;14:2819-30.
    • (2000) Genes Dev. , vol.14 , pp. 2819-2830
    • Repa, J.J.1    Liang, G.2    Ou, J.3    Bashmakov, Y.4    Lobaccaro, J.M.5    Shimomura, I.6
  • 29
    • 0037192797 scopus 로고    scopus 로고
    • Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
    • Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, et al. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem. 2002;277:11019-25.
    • (2002) J Biol Chem. , vol.277 , pp. 11019-11025
    • Joseph, S.B.1    Laffitte, B.A.2    Patel, P.H.3    Watson, M.A.4    Matsukuma, K.E.5    Walczak, R.6
  • 30
    • 5144232850 scopus 로고    scopus 로고
    • A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation
    • Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R, et al. A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proc Natl Acad Sci USA. 2004;101:14461-6.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , pp. 14461-14466
    • Ogawa, S.1    Lozach, J.2    Jepsen, K.3    Sawka-Verhelle, D.4    Perissi, V.5    Sasik, R.6
  • 31
    • 79951780039 scopus 로고    scopus 로고
    • Coronin 2A mediates actin-dependent de-repression of inflammatory response genes
    • Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, et al. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011;470:414-8.
    • (2011) Nature. , vol.470 , pp. 414-418
    • Huang, W.1    Ghisletti, S.2    Saijo, K.3    Gandhi, M.4    Aouadi, M.5    Tesz, G.J.6
  • 32
    • 10344255627 scopus 로고    scopus 로고
    • Signal transduction pathways: New targets for treating rheumatoid arthritis
    • Morel J, Berenbaum F. Signal transduction pathways: new targets for treating rheumatoid arthritis. Joint Bone Spine. 2004;71:503-10.
    • (2004) Joint Bone Spine. , vol.71 , pp. 503-510
    • Morel, J.1    Berenbaum, F.2
  • 33
    • 2642517290 scopus 로고    scopus 로고
    • Increased synovial tissue NF-κB1 expression at sites adjacent to the cartilage-pannus junction in rheumatoid arthritis
    • Benito MJ, Murphy E, Murphy EP, Van den Berg WB, FitzGerald O, Bresnihan B. Increased synovial tissue NF-κB1 expression at sites adjacent to the cartilage-pannus junction in rheumatoid arthritis. Arthritis Rheum. 2004;50:1781-7.
    • (2004) Arthritis Rheum. , vol.50 , pp. 1781-1787
    • Benito, M.J.1    Murphy, E.2    Murphy, E.P.3    Van Den Berg, W.B.4    Fitzgerald, O.5    Bresnihan, B.6
  • 34
    • 66849143692 scopus 로고    scopus 로고
    • Pathogenesis of rheumatoid arthritis and c-Fos/AP-1
    • Shiozawa S, Tsumiyama K. Pathogenesis of rheumatoid arthritis and c-Fos/AP-1. Cell Cycle. 2009;8:1539-43.
    • (2009) Cell Cycle. , vol.8 , pp. 1539-1543
    • Shiozawa, S.1    Tsumiyama, K.2
  • 35
    • 0031559597 scopus 로고    scopus 로고
    • The nuclear receptor corepressor SMRT inhibits interstitial collagenase (MMP-1) transcription through an HRE-independent mechanism
    • Schroen DJ, Chen JD, Vincenti MP, Brinckerhoff CE. The nuclear receptor corepressor SMRT inhibits interstitial collagenase (MMP-1) transcription through an HRE-independent mechanism. Biochem Biophys Res Commun. 1997;237:52-8.
    • (1997) Biochem Biophys Res Commun. , vol.237 , pp. 52-58
    • Schroen, D.J.1    Chen, J.D.2    Vincenti, M.P.3    Brinckerhoff, C.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.