Epigenetic ThPOK silencing limits the time window to choose CD4+ helper-lineage fate in the thymus

EMBO Journal

Volumn 32, Issue 8, 2013, Pages 1183-1194

  Tanaka, Hirokazu ^a   Naito, Taku ^a,c   Muroi, Sawako ^a   Seo, Wooseok ^a   Chihara, Risa ^a   Miyamoto, Chizuko ^a   Kominami, Ryo ^b   Taniuchi, Ichiro ^a  

^a Institute of Physical and Chemical Research   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^c TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

cell fate; epigenetics; gene silencing; T cell development; ThPOK

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FATE; CELL LINEAGE; CHROMATIN STRUCTURE; CONTROLLED STUDY; COPY NUMBER VARIATION; CYTOTOXICITY; EPIGENETICS; GENE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; MICE; MICE, TRANSGENIC; THYMUS GLAND; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84876419847     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.47     Document Type: Article

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