Effects of telmisartan or amlodipine monotherapy versus telmisartan/amlodipine combination therapy on vascular dysfunction and oxidative stress in diabetic rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 5, 2013, Pages 405-419

  Mollnau, Hanke ^a   Oelze, Matthias ^a   Zinßius, Elena ^a   Hausding, Michael ^a   Wu, Zhixiong ^a   Knorr, Maike ^a   Ghaemi Kerahrodi, Jasmin ^a   Kröller Schön, Swenja ^a   Jansen, Thomas ^a   Teutsch, Christine ^b   Foster, Carolyn ^b   Li, Huige ^a   Wenzel, Philip ^a   Schulz, Eberhard ^a   Münzel, Thomas ^a,c   Daiber, Andreas ^a,c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

AT1 receptor blockade; Calcium antagonism; Endothelial dysfunction; Streptozotocin; Type 1 diabetes; Vascular oxidative stress

Indexed keywords

AMLODIPINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TELMISARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENDOTHELIUM CELL; HYPOTENSION; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE; MALE; MONOTHERAPY; NONHUMAN; OXIDATIVE STRESS; RAT; REGULATORY MECHANISM; RESPIRATORY BURST; STAINING; STREPTOZOCIN DIABETES; VASCULAR DISEASE; VASOCONSTRICTION;

AMLODIPINE; ANIMALS; BENZIMIDAZOLES; BENZOATES; DIABETES MELLITUS, EXPERIMENTAL; DRUG COMBINATIONS; ENDOTHELIUM, VASCULAR; MALE; ORGAN CULTURE TECHNIQUES; OXIDATIVE STRESS; RATS; RATS, WISTAR; TREATMENT OUTCOME;

EID: 84876406689     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0842-7     Document Type: Article

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