메뉴 건너뛰기




Volumn 56, Issue 3, 2013, Pages 315-320

Association of T916C (Y257H) mutation in Candida albicans ERG11 with fluconazole resistance

Author keywords

Candida albicans; Drug resistance; Fluconazole; Lanosterol 14a demethylase

Indexed keywords

FLUCONAZOLE;

EID: 84876324014     PISSN: 09337407     EISSN: 14390507     Source Type: Journal    
DOI: 10.1111/myc.12027     Document Type: Article
Times cited : (10)

References (26)
  • 1
    • 79951603061 scopus 로고    scopus 로고
    • Investigation of mutations in Erg11 gene of fluconazole resistant Candida albicans isolates from Turkish hospitals
    • Manastir L, Ergon MC, Yucesoy M. Investigation of mutations in Erg11 gene of fluconazole resistant Candida albicans isolates from Turkish hospitals. Mycoses 2011; 54: 99-104.
    • (2011) Mycoses , vol.54 , pp. 99-104
    • Manastir, L.1    Ergon, M.C.2    Yucesoy, M.3
  • 2
    • 79959187026 scopus 로고    scopus 로고
    • Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance
    • Alvarez-Rueda N, Fleury A, Morio F et al. Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance. PLoS ONE 2011; 6: e21239.
    • (2011) PLoS ONE , vol.6
    • Alvarez-Rueda, N.1    Fleury, A.2    Morio, F.3
  • 3
    • 41149159789 scopus 로고    scopus 로고
    • Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations
    • Xu Y, Chen L, Li C. Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations. J Antimicrob Chemother 2008; 61: 798-804.
    • (2008) J Antimicrob Chemother , vol.61 , pp. 798-804
    • Xu, Y.1    Chen, L.2    Li, C.3
  • 4
    • 0033986849 scopus 로고    scopus 로고
    • The R467K amino acid substitution in Candida albicans sterol 14α-demethylase causes drug resistance through reduced affinity
    • Lamb DC, Kelly DE, White TC et al. The R467K amino acid substitution in Candida albicans sterol 14α-demethylase causes drug resistance through reduced affinity. Antimicrob Agents Chemother 2000; 44: 63-7.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 63-67
    • Lamb, D.C.1    Kelly, D.E.2    White, T.C.3
  • 5
    • 0031054924 scopus 로고    scopus 로고
    • The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity
    • Lamb DC, Kelly DE, Schunck WH et al. The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity. J Biol Chem 1997; 272: 5682-8.
    • (1997) J Biol Chem , vol.272 , pp. 5682-5688
    • Lamb, D.C.1    Kelly, D.E.2    Schunck, W.H.3
  • 6
    • 6444224766 scopus 로고    scopus 로고
    • Studies on the regulation of the two-component histidine kinase gene CHK1 in Candida albicans using the heterologous lacZ reporter gene
    • Li D, Gurkovska V, Sheridan M et al. Studies on the regulation of the two-component histidine kinase gene CHK1 in Candida albicans using the heterologous lacZ reporter gene. Microbiology 2004; 150: 3305-13.
    • (2004) Microbiology , vol.150 , pp. 3305-3313
    • Li, D.1    Gurkovska, V.2    Sheridan, M.3
  • 7
    • 0028308104 scopus 로고
    • [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae
    • Wickner RB. [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science 1994; 264: 566-9.
    • (1994) Science , vol.264 , pp. 566-569
    • Wickner, R.B.1
  • 8
    • 33750070351 scopus 로고    scopus 로고
    • New pFA-cassettes for PCR-based gene manipulation in Candida albicans
    • Schaub Y, Dunkler A, Walther A et al. New pFA-cassettes for PCR-based gene manipulation in Candida albicans. J Basic Microbiol 2006; 46: 416-29.
    • (2006) J Basic Microbiol , vol.46 , pp. 416-429
    • Schaub, Y.1    Dunkler, A.2    Walther, A.3
  • 9
    • 4644220750 scopus 로고    scopus 로고
    • Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi
    • Yu JH, Hamari Z, Han KH et al. Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi. Fungal Genet Biol 2004; 41: 973-81.
    • (2004) Fungal Genet Biol , vol.41 , pp. 973-981
    • Yu, J.H.1    Hamari, Z.2    Han, K.H.3
  • 10
    • 34347206860 scopus 로고    scopus 로고
    • High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
    • Gietz RD, Schiestl RH. High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2007; 2: 31-4.
    • (2007) Nat Protoc , vol.2 , pp. 31-34
    • Gietz, R.D.1    Schiestl, R.H.2
  • 11
    • 77953721380 scopus 로고    scopus 로고
    • Overexpression of CDR1 and CDR2 genes plays an important role in fluconazole resistance in Candida albicans with G487T and T916C mutations
    • Chen LM, Xu YH, Zhou CL et al. Overexpression of CDR1 and CDR2 genes plays an important role in fluconazole resistance in Candida albicans with G487T and T916C mutations. J Int Med Res 2010; 38: 536-45.
    • (2010) J Int Med Res , vol.38 , pp. 536-545
    • Chen, L.M.1    Xu, Y.H.2    Zhou, C.L.3
  • 13
    • 0031759244 scopus 로고    scopus 로고
    • Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains
    • Franz R, Kelly SL, Lamb DC et al. Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains. Antimicrob Agents Chemother 1998; 42: 3065-72.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3065-3072
    • Franz, R.1    Kelly, S.L.2    Lamb, D.C.3
  • 14
    • 0036093372 scopus 로고    scopus 로고
    • Resistance mechanisms in clinical isolates of Candida albicans
    • White TC, Holleman S, Dy F et al. Resistance mechanisms in clinical isolates of Candida albicans. Antimicrob Agents Chemother 2002; 46: 1704-13.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1704-1713
    • White, T.C.1    Holleman, S.2    Dy, F.3
  • 15
    • 4644248400 scopus 로고    scopus 로고
    • Development and characterization of an in vivo central venous catheter Candida albicans biofilm model
    • Andes D, Nett J, Oschel P et al. Development and characterization of an in vivo central venous catheter Candida albicans biofilm model. Infect Immun 2004; 72: 6023-31.
    • (2004) Infect Immun , vol.72 , pp. 6023-6031
    • Andes, D.1    Nett, J.2    Oschel, P.3
  • 16
    • 0033824935 scopus 로고    scopus 로고
    • Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
    • Baillie GS, Douglas LJ. Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents. J Antimicrob Chemother 2000; 46: 397-403.
    • (2000) J Antimicrob Chemother , vol.46 , pp. 397-403
    • Baillie, G.S.1    Douglas, L.J.2
  • 17
    • 78049243452 scopus 로고    scopus 로고
    • Identification and characterization of four azole-resistant erg3 mutants of Candida albicans
    • Martel CM, Parker JE, Bader O et al. Identification and characterization of four azole-resistant erg3 mutants of Candida albicans. Antimicrob Agents Chemother 2010; 54: 4527-33.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4527-4533
    • Martel, C.M.1    Parker, J.E.2    Bader, O.3
  • 18
    • 84865368550 scopus 로고    scopus 로고
    • Amino acid substitutions in the Candida albicans sterol {Delta}5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence
    • Morio F, Pagniez F, Lacroix C et al. Amino acid substitutions in the Candida albicans sterol {Delta}5, 6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence. J Antimicrob Chemother 2012; 67: 2131-8.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2131-2138
    • Morio, F.1    Pagniez, F.2    Lacroix, C.3
  • 19
    • 77749291956 scopus 로고    scopus 로고
    • Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature
    • Morio F, Loge C, Besse B et al. Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature. Diagn Microbiol Infect Dis 2010; 66: 373-84.
    • (2010) Diagn Microbiol Infect Dis , vol.66 , pp. 373-384
    • Morio, F.1    Loge, C.2    Besse, B.3
  • 20
    • 77949344512 scopus 로고    scopus 로고
    • Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene
    • Feng LJ, Wan Z, Wang XH et al. Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene. Chin Med J (Engl) 2010; 123: 544-8.
    • (2010) Chin Med J (Engl) , vol.123 , pp. 544-548
    • Feng, L.J.1    Wan, Z.2    Wang, X.H.3
  • 21
    • 2542494102 scopus 로고    scopus 로고
    • Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles
    • Chau AS, Mendrick CA, Sabatelli FJ et al. Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles. Antimicrob Agents Chemother 2004; 48: 2124-31.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2124-2131
    • Chau, A.S.1    Mendrick, C.A.2    Sabatelli, F.J.3
  • 22
    • 0346784897 scopus 로고    scopus 로고
    • Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding
    • Xiao L, Madison V, Chau AS et al. Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding. Antimicrob Agents Chemother 2004; 48: 568-74.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 568-574
    • Xiao, L.1    Madison, V.2    Chau, A.S.3
  • 23
    • 33746086078 scopus 로고    scopus 로고
    • Synergistic effect of terbinafine combined with fluconazole or itraconazole on stable fluconazole-resistant Candida albicans induced by fluconazole in vitro
    • Jiang W, Tan S, Jiang G. Synergistic effect of terbinafine combined with fluconazole or itraconazole on stable fluconazole-resistant Candida albicans induced by fluconazole in vitro. Chin J Microbiol Immunol 2006; 26: 360-4.
    • (2006) Chin J Microbiol Immunol , vol.26 , pp. 360-364
    • Jiang, W.1    Tan, S.2    Jiang, G.3
  • 24
    • 4143053761 scopus 로고    scopus 로고
    • Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions
    • Sheng C, Zhang W, Zhang M et al. Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions. J Biomol Struct Dyn 2004; 22: 91-9.
    • (2004) J Biomol Struct Dyn , vol.22 , pp. 91-99
    • Sheng, C.1    Zhang, W.2    Zhang, M.3
  • 25
    • 0033753060 scopus 로고    scopus 로고
    • Genetic analysis of azole resistance in the Darlington strain of Candida albicans
    • Kakeya H, Miyazaki Y, Miyazaki H et al. Genetic analysis of azole resistance in the Darlington strain of Candida albicans. Antimicrob Agents Chemother 2000; 44: 2985-90.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2985-2990
    • Kakeya, H.1    Miyazaki, Y.2    Miyazaki, H.3
  • 26
    • 0031938057 scopus 로고    scopus 로고
    • Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents
    • Sanglard D, Ischer F, Koymans L et al. Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents. Antimicrob Agents Chemother 1998; 42: 241-53.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 241-253
    • Sanglard, D.1    Ischer, F.2    Koymans, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.