A Panel of Quantitative Calux® Reporter Gene Assays for Reliable High-Throughput Toxicity Screening of Chemicals and Complex Mixtures

High-Throughput Screening Methods in Toxicity Testing

Volumn , Issue , 2013, Pages 519-532

  van der Burg, Bart ^a   van der Linden, Sander ^a   Man, Hai Yen ^a   Winter, Roos ^a   Jonker, Lydia ^a   van Vugt Lussenburg, Barbara ^a   Brouwer, Abraham ^a,b  

^a BIODETECTION SYSTEMS B V   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Chemicals; Environment; Food; High throughput screening; Reporter gene assays; Toxicity

Indexed keywords

EID: 84876322827     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118538203.ch28     Document Type: Chapter

References (35)

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30. Schenk, B., Weimer, M., Bremer, S., van der Burg, B., Cortvrindt, R., Freyberger, A., Lazzari, G., Pellizzer, C., Piersma, A., Scḧafer, W.R., Seiler, A., Witters, H., Schwarz, M. (2010). The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants. Reproductive Toxicology, 30, 200-218.
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34. Van der Linden, S.C., von Bergh A.R.M., Van Vugt-Lussenburg B., Jonker L., Brouwer A., Teunis M., Krul C.A.M., Van der Burg B. Development of a panel of high throughput reporter gene assays to detect genotoxicity and oxidative stress, submitted.
35. Piersma, A.H., Schulpen, S.H.W., Uibel, F., Van Vugt-Lussenburg, B., Bosgra, S., Hermsen, S.A.B., Roelofs, M.J.E., Man, H., Jonker, L., Van der Linden, S., Van Duursen, M.B.M.,Wolterbeek, A.P.M., Schwarz, M., Kroese, E.D., Van der Burg, B. Evaluation of an alternative in vitro test battery for detecting reproductive toxicants, submitted.