Estrogenic and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses

Chemosphere

Volumn 65, Issue 11, 2006, Pages 2244-2252

  Houtman, Corine J ^a   Booij, Petra ^a   Jover, Eric ^b,c   Pascual del Rio, David ^a   Swart, Kees ^a   van Velzen, Martin ^a   Vreuls, Rene ^c   Legler, Juliette ^a   Brouwer, Abraham ^a   Lamoree, Marja H ^a  

^a INSTITUTE FOR ENVIRONMENTAL STUDIES   (Netherlands)

^b DEPARTMENT OF ENVIRONMENTAL CHEMISTRY   (Spain)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Bioassay directed fractionation; Hormones; Polycylic aromatic hydrocarbons; Sediment; Toxicity identification and evaluation

Indexed keywords

BIOASSAY; FRACTIONATION; GAS CHROMATOGRAPHY; HORMONES; MASS SPECTROMETRY;

ESTROGENIC ACTIVITIES; TOXICITY EVALUATION; TOXICITY IDENTIFICATION;

SEDIMENTS;

DIOXIN; ESTRADIOL; ESTROGEN; ESTRONE; POLYCYCLIC AROMATIC HYDROCARBON;

BIOASSAY; FRACTIONATION; GAS CHROMATOGRAPHY; HORMONES; MASS SPECTROMETRY; SEDIMENTS;

BIOASSAY; DIOXIN; ESTROGENIC COMPOUND; FRACTIONATION; GAS CHROMATOGRAPHY; HARBOR; IDENTIFICATION METHOD; SEDIMENT CHEMISTRY; SEDIMENT POLLUTION; TOXICITY;

ANALYTIC METHOD; ARTICLE; BIOASSAY; CHEMICAL ANALYSIS; ESTROGEN ACTIVITY; FRACTIONATION; GAS CHROMATOGRAPHY; GEOGRAPHIC DISTRIBUTION; ION TRAP MASS SPECTROMETRY; NETHERLANDS; REPORTER GENE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEDIMENT; TIME OF FLIGHT MASS SPECTROMETRY;

BENELUX; EURASIA; EUROPE; NETHERLANDS; WESTERN EUROPE; ZEELAND; ZIERIKZEE;

EID: 33750966478     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2006.05.043     Document Type: Article

References (32)

1. Brack W. Effect-directed analysis: a promising tool for the identification of organic toxicants in complex mixtures?. Analytical and Bioanalytical Chemistry 377 (2003) 397-407
2. Brack W., Schirmer K., Kind T., Schrader S., and Schuurmann G. Effect-directed fractionation and identification of cytochrome P4501A-inducing halogenated aromatic hydrocarbons in a contaminated sediment. Environmental Toxicology and Chemistry 21 (2002) 2654-2662
3. Cespedes R., Petrovic M., Raldua D., Saura U., Pina B., Lacorte S., Viana P., and Barcelo D. Integrated procedure for determination of endocrine-disrupting activity in surface waters and sediments by use of the biological technique recombinant yeast assay and chemical analysis by LC-ESI-MS. Analytical and Bioanalytical Chemistry 378 (2004) 697-708
4. Cheung Y.L., Gray T.J.B., and Ioannides C. Mutagenicity of chrysene, its methyl and benzo derivatives, and their interactions with Cytochromes-P-450 and the Ah-receptor-relevance to their carcinogenic potency. Toxicology 81 (1993) 69-86
5. Desbrow C., Routledge E.J., Brighty G.C., Sumpter J.P., and Waldock M. Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening. Environmental Science & Technology 32 (1998) 1549-1558
6. Fernandez P., and Bayona J.M. Use of off-line gelpermeation chromatography normal-phase liquid chromatography for the determination of polycyclic aromatic compounds in environmental samples and standard reference materials (air particulate matter and marine sediment). Journal of Chromatography 625 (1992) 141-149
7. Gibson R., Smith M.D., Spary C.J., Tyler C.R., and Hill E.M. Mixtures of estrogenic contaminants in bile of fish exposed to wastewater treatment works effluents. Environmental Science & Technology 39 (2005) 2461-2471
8. Hansch C., Leo A., and Hoekman D. Exploring QSAR (1995), American Chemical Society, Washington, DC
9. Houtman C.J., Cenijn P.H., Hamers T., Lamoree M.H., Legler J., Murk A.J., and Brouwer A. Toxicological profiling of sediments with in vitro bioassays with emphasis on endocrine disruption. Environmental Toxicology and Chemistry 23 (2004) 32-40
10. Houtman C.J., van Oostveen A.M., Brouwer A., Lamoree M.H., and Legler J. Identification of estrogenic compounds in fish bile using bioassay directed fractionation. Environmental Science & Technology 38 (2004) 6415-6423
11. Houtman C.J., Swart C.P., Lamoree M.H., Legler J., and Brouwer A. DR- and ER-CALUX assays as tools to direct toxicity identification and evaluation of endocrine disrupting chemicals. Organohalogen Compounds 58 (2002) 349-352
12. Houtman C.J., van Houten Y.K., Leonards P.E.G., Brouwer A., Lamoree M.H., and Legler J. Biological validation of a sample preparation method for ER-CALUX bioanalysis of estrogenic activity in sediment using mixtures of (xeno-)estrogens. Environmental Science & Technology 40 (2006) 2455-2461
13. Khim J.S., Villeneuve D.L., Kannan K., Koh C.H., and Giesy J.P. Characterization and distribution of trace organic contaminants in sediment from Masan Bay, Korea. 2. in vitro gene expression assays. Environmental Science & Technology 33 (1999) 4206-4211
14. Khim J.S., Lee K.T., Villeneuve D.L., Kannan K., Giesy J.P., and Koh C.H. In vitro bioassay determination of dioxin-like and estrogenic activity in sediment and water from Ulsan Bay and its vicinity, Korea. Archives of Environmental Contamination and Toxicology 40 (2001) 151-160
15. Klamer H.J.C., Leonards P.E.G., Lamoree M.H., Villerius L.A., Akerman J.E., and Bakker J.F. A chemical and toxicological profile of Dutch North Sea surface sediments. Chemosphere 58 (2005) 1579-1587
16. Legler J., van den Brink C.E., Brouwer A., Murk A.J., van der Saag P.T., Vethaak A.D., and van der Burg B. Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. Toxicological Sciences 48 (1999) 55-66
17. Legler J., Dennekamp M., Vethaak A.D., Brouwer A., Koeman J.H., van der Burg B., and Murk A.J. Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays. The Science of the Total Environment 293 (2002) 69-83
18. Legler J., Leonards P., Spenkelink A., and Murk A.J. In vitro biomonitoring in polar extracts of solid phase matrices reveals the presence of unknown compounds with estrogenic activity. Ecotoxicology 12 (2003) 239-249
19. Loewe S., and Muischnek H. Über Kombinationswirkungen. 1. Mitteilung: Hilfsmittel der Fragestellung. Naunyn-Schmiedelbergs. Arch Exp Pathol Pharmakol 114 (1926) 313-326
20. Machala M., Vondracek J., Blaha L., Ciganek M., and Neca J. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay. Mutation Research-Genetic Toxicology and Environmental Mutagenesis 497 (2001) 49-62
21. Mills L.J., and Chichester C. Review of evidence: are endocrine-disrupting chemicals in the aquatic environment impacting fish populations?. Science of the Total Environment 343 (2005) 1-34
22. Murk A.J., Legler J., Denison M.S., Giesy J.P., van de Guchte C., and Brouwer A. Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water. Fundamental and Applied Toxicology 33 (1996) 149-160
23. Peck M., Gibson R.W., Kortenkamp A., and Hill E.M. Sediments are major sinks of steroidal estrogens in two United Kingdom rivers. Environmental Toxicology and Chemistry 23 (2004) 945-952
24. Reddy S., and Brownawell B.J. Analysis of estrogens in sediment from a sewage-impacted urban estuary using high-performance liquid chromatography/time-of-flight mass spectrometry. Environmental Toxicology and Chemistry 24 (2005) 1041-1047
25. Snyder S.A., Villeneuve D.L., Snyder E.M., and Giesy J.P. Identification and quantification of estrogen receptor agonists in wastewater effluents. Environmental Science & Technology 35 (2001) 3620-3625
26. Thomas K.V., Hurst M.R., Matthiesen P., and Waldock M. Characterization of estrogenic compounds in water samples collected from United Kingdom estuaries. Environmental Toxicology and Chemistry 20 (2001) 2165-2170
27. Thomas K.V., Balaam J., Hurst M., Nedyalkova Z., and Mekenyan O. Potency and characterization of estrogen-receptor agonists in united kingdom estuarine sediments. Environmental Toxicology and Chemistry 23 (2004) 471-479
28. Thomas K.V., Balaam J., Hurst M.R., and Thain J.E. Identification of in vitro estrogen and androgen receptor agonists in North Sea offshore produced water discharges. Environmental Toxicology and Chemistry 23 (2004) 1156-1163
29. Verbruggen E.M.J., Klamer J.C., Villerius L., Brinkman U.A.Th., and Hermens J.L.M. Gradient elution reversed-phase high-performance liquid chromatography for fractionation of complex mixtures of organic micropollutants according to hydrophobicity using isocratic retention parameters. Journal of Chromatography A 835 (1999) 19-27
30. Vondrácek J., Machala M., Minksová K., Bláha M., Murk A.J., Kozubík A., Hofmanová J., Hilscherová K., Ulrich R., Ciganek M., Neca J., Svrcková D., and Holoubek I. Monitoring sediments contaminated predominantly with polyaromatic hydrocarbons by chemical and in vitro bioassay techniques. Environmental Toxicology and Chemistry 20 (2001) 1499-1506
31. Vos J.G., Dybing E., Greim H.A., Ladefoged O., Lambré C., Tarazona J.V., Brandt I., and Vethaak A.D. Health effects of endocrine disrupting chemicals on wildlife, with special reference to the European situation. Critical Reviews in Toxicology 30 (2000) 71-133
32. Wong H.L., Giesy J.P., Siu W.H.L., and Lam P.K.S. Estrogenic and dioxin-like activities and cytotoxicity of sediments and biota from Hong Kong mudflats. Archives of Environmental Contamination and Toxicology 48 (2005) 575-586