Cardiac Na+-Ca2+ exchanger: Dynamics of Ca2+-dependent activation and deactivation in intact myocytes

Journal of Physiology

Volumn 591, Issue 8, 2013, Pages 2067-2086

  Ginsburg, Kenneth S ^a   Weber, Christopher R ^b   Bers, Donald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; SODIUM CALCIUM EXCHANGE PROTEIN; CALCIUM; SODIUM;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; ELECTROSTIMULATION; EXCITATION CONTRACTION COUPLING; HEART MUSCLE CELL; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; RABBIT; SARCOPLASMIC RETICULUM; SODIUM TRANSPORT; ANIMAL; BIOLOGICAL MODEL; IN VITRO STUDY; PHYSIOLOGY;

ANIMALS; CALCIUM; MICE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; RABBITS; SARCOPLASMIC RETICULUM; SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 84876316104     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.252080     Document Type: Article

References (88)

1. 2+ exchange currents. J Physiol 589, 2569-2583.
2. 2+-exchanger in rat ventricular myocytes. J Mol Cell Cardiol 30, 2437-2447.
3. +"fuzzy space": does it exist, and is it important in ischemic injury J Cardiovasc Electrophysiol 17(Suppl 1), S43-S46.
4. Bassani JWM, Bassani RA & Bers DM (1994). Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms. J Physiol 476, 279-293.
5. Bassani RA, Bassani JW, Lipsius SL & Bers DM (1997). Diastolic SR Ca efflux in atrial pacemaker cells and Ca-overloaded myocytes. Am J Physiol Heart Circ Physiol 273, H886-H892.
6. Bassani RA & Bers DM (1994). Na-Ca exchange is required for rest-decay but not for rest-potentiation of twitches in rabbit and rat ventricular myocytes. J Mol Cell Cardiol 26, 1335-1347.
7. Bers DM (1987). Mechanisms contributing to the cardiac inotropic effect of Na pump inhibition and reduction of extracellular Na. J Gen Physiol 90, 479-504.
8. Bers DM & Ellis D (1982). Intracellular calcium and sodium activity in sheep heart Purkinje fibres. Effect of changes of external sodium and intracellular pH. Pflugers Arch 393, 171-178.
9. Bers DM & Ginsburg KS (2007). Na:Ca stoichiometry and cytosolic Ca-dependent activation of NCX in intact cardiomyocytes. Ann N Y Acad Sci 1099, 326-338.
10. 2+ exchanger is essential for regulation: crystal structures and mutational analysis. Proc Natl Acad Sci U S A 104, 18467-18472.
11. 2+ exchanger. J Biol Chem 286, 28811-28820.
12. Boyman L, Mikhasenko H, Hiller R & Khananshvili D (2009). Kinetic and equilibrium properties of regulatory calcium sensors of NCX1 protein. J Biol Chem 284, 6185-6193.
13. 2+-pumping system in dog heart sarcolemma. Nature 283, 765-767.
14. 2+-pumping ATPase of heart sarcolemma by a phosphorylation-dephosphorylation process. J Biol Chem 256, 9371-9373.
15. Chernaya G, Vázquez M & Reeves JP (1996). Sodium-calcium exchange and store-dependent calcium influx in transfected Chinese hamster ovary cells expressing the bovine cardiac sodium-calcium exchanger. Acceleration of exchange activity in thapsigargin-treated cells. J Biol Chem 271, 5378-5385.
16. Chernysh O, Condrescu M & Reeves JP (2004). Calcium-dependent regulation of calcium efflux by the cardiac sodium/calcium exchanger. Am J Physiol Cell Physiol 287, C797-C806.
17. 2+-ATPase in the regulation of resting calcium concentration in rat ventricular myocytes. J Physiol 515, 109-118.
18. Choi HS, Trafford AW & Eisner DA (2000). Measurement of calcium entry and exit in quiescent rat ventricular myocytes. Pflugers Arch 440, 600-608.
19. 2+ exchange current by MgATP. J Physiol 454, 27-57.
20. Condrescu M, Chernaya G, Kalaria V & Reeves JP (1997). Barium influx mediated by the cardiac sodium-calcium exchanger in transfected Chinese hamster ovary cells. J Gen Physiol 109, 41-51.
21. 2+ exchanger and ryanodine receptor during development. Biophys J 93, 2504-2518.
22. i depletion and Na buffering. Biophys J 84, 4157-4166.
23. + concentration is elevated in heart failure but Na/K pump function is unchanged. Circulation 105, 2543-2548.
24. DiPolo R (1979). Calcium influx in internally dialyzed squid giant axons. J Gen Physiol 73, 91-113.
25. DiPolo R & Beaugé L (2006). Sodium/calcium exchanger: influence of metabolic regulation on ion carrier interactions. Physiol Rev 86, 155-203.
26. Eisner DA, Lederer WJ & Vaughan-Jones RD (1984). The quantitative relationship between twitch tension and intracellular sodium activity in sheep cardiac Purkinje fibres. J Physiol 355, 251-266.
27. Eisner DA, Trafford AW, Díaz ME, Overend CL & O'Neill SC (1998). The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation. Cardiovasc Res 38, 589-604.
28. 2+ in transfected Chinese hamster ovary cells. Am J Physiol Cell Physiol 275, C50-C55.
29. 2+ exchange current in guinea-pig ventricular myocytes. J Physiol 529, 611-623.
30. i in a restricted space of guinea-pig ventricular cells. J Physiol 509, 457-470.
31. Ginsburg KS & Bers DM (2010). Cytosolic Ca-dependent Na/Ca exchange regulation in intact cardiomyocytes: role of cytosolic Na. Biophys J 98(Supp1), 21a-22a.
32. Goldhaber JI, Lamp ST, Walter DO, Garfinkel A, Fukumoto GH & Weiss JN (1999). Local regulation of the threshold for calcium sparks in rat ventricular myocytes: role of sodium-calcium exchange. J Physiol 520, 431-438.
33. Grandi E, Puglisi JL, Wagner S, Maier LS, Severi S & Bers DM (2007). Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials. Biophys J 93, 3835-3847.
34. Haworth RA & Goknur AB (1991). Control of the Na-Ca exchanger in isolated heart cells. II. Beat-dependent activation in normal cells by intracellular calcium. Circ Res 69, 1514-1524.
35. Haworth RA Goknur AB & Hunter DR (1991). Control of the Na-Ca exchanger in isolated heart cells. I. Induction of Na-Na exchange in sodium-loaded cells by intracellular calcium. Circ Res 69, 1506-1513.
36. 2+ exchanger. Ann N Y Acad Sci 1099, 7-15.
37. 2+ sensors. Mol Cell 22, 15-25.
38. 2+ exchange in giant excised sarcolemmal membrane patches. Nature 344, 242-245.
39. 2+ exchanger. Am J Physiol Cell Physiol 287, C1167-C1172.
40. ATP potassium channels by PIP2. Science 273, 956-959.
41. Hilgemann DW, Collins A & Matsuoka S (1992). Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP. J Gen Physiol 100, 933-961.
42. Hilgemann DW, Yaradanakul A, Wang Y & Fuster D (2006). Molecular control of cardiac sodium homeostasis in health and disease. J Cardiovasc Electrophysiol 17(Suppl S1), S47-S56.
43. 2+ exchanger dimers. Proc Natl Acad Sci U S A 108, 1699-1704.
44. 2+ exchanger. Nature 427, 544-548.
45. 2+ concentration jump. Biophys J 71, 2473-2485.
46. Kimura J, Noma A & Irisawa H (1986). Na-Ca exchange in mammalian heart cells. Nature 319, 596-597.
47. 2+ exchange in the positive staircase of contraction in guinea-pig ventricular myocytes. Pflugers Arch 446, 347-355.
48. Lamont C & Eisner DA (1996). The sarcolemmal mechanisms involved in the control of diastolic intracellular calcium in isolated rat cardiac trabeculae. Pflugers Arch 432, 961-969.
49. Lester WC, Schroder EA, Burgess DE, Yozwiak D, Andres DA & Satin J (2008). Steady-state coupling of plasma membrane calcium entry to extrusion revealed by novel L-type calcium channel block. Cell Calcium 44, 353-362.
50. 2+ exchanger. Mol Cell Biochem 160-161, 27-32.
51. 2+ exchanger. J Biol Chem 269, 22847-22852.
52. Litwin SE, Li J & Bridge JHB (1998). Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: studies in adult rabbit ventricular myocytes. Biophys J 75, 359-371.
53. Livshitz L, Acsai K, Antoons G, Sipido K & Rudy Y (2012). Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes. J Physiol 590, 4423-4446.
54. Luo C-H & Rudy Y (1994). A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ Res 74, 1071-1096.
55. Maack C, Ganesan A, Sidor A & O'Rourke B (2005). Cardiac sodium-calcium exchanger is regulated by allosteric calcium and exchanger inhibitory peptide at distinct sites. Circ Res 96, 91-99.
56. 2+ exchange current in guinea-pig ventricular myocytes. J Physiol 476, 443-458.
57. 2+-binding domain. J Gen Physiol 105, 403-420.
58. 2+ exchanger whole-cell, native excised, and cloned-excised properties. Ann N Y Acad Sci 779, 159-170.
59. Miura Y & Kimura J (1989). Sodium-calcium exchange current. Dependence on internal Ca and Na and competitive binding of external Na and Ca. J Gen Physiol 93, 1129-1145.
60. Mullins LJ (1979). The generation of electric currents in cardiac fibers by Na/Ca exchange. Am J Physiol Cell Physiol 236, C103-C110.
61. Neco P, Rose B, Huynh N, Zhang R, Bridge JHB, Philipson KD & Goldhaber JI (2010). Sodium-calcium exchange is essential for effective triggering of calcium release in mouse heart. Biophys J 99, 755-764.
62. 2+ exchanger. Science 250, 562-565.
63. 2+ during operation of sodium-calcium exchange in guinea-pig heart cells. J Physiol 442, 257-276.
64. 2+ exchanger detected by FRET. Biophys J 87, 899-906.
65. 2+ current in cardiac excitation-contraction coupling during action potentials. Basic Res Cardiol 106, 967-977.
66. 2+ homeostasis. J Bioenerg Biomembr 30, 151-160.
67. Reeves JP & Condrescu M (2003). Allosteric activation of sodium-calcium exchange activity by calcium: persistence at low calcium concentrations. J Gen Physiol 122, 621-639.
68. Reeves JP & Hale CC (1984). The stoichiometry of the cardiac sodium-calcium exchange system. J Biol Chem 259, 7733-7739.
69. 2+. Am J Physiol Cell Physiol 252, C17-C23.
70. Sato D, Despa S & Bers DM (2012). Can the sodium-calcium exchanger initiate or suppress calcium sparks in cardiac myocytes Biophys J 102, L31-L33.
71. 2+ overload in rat ventricular myocytes. Circulation 101, 1441-1446.
72. Segal IH (1993). Enzyme Kinetics: Behaviour and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems Wiley, New York .
73. Shannon TR, Wang F, Puglisi J, Weber C & Bers DM (2004). A mathematical treatment of integrated Ca dynamics within the ventricular myocyte. Biophys J 87, 3351-3371.
74. 2+ dynamics in ventricular myocytes. Prog Biophys Mol Biol 96, 377-398.
75. Sheu SS & Fozzard HA (1982). Transmembrane Na and Ca electrochemical gradients in cardiac muscle and their relation to force development. J Gen Physiol 80, 325-351.
76. 2+ exchange. Circ Res 81, 1034-1044.
77. 2+ release in ventricular myocytes. Biophys J 94, L54-L56.
78. 2+ exchanger-mediated relaxation in rabbit ventricular myocytes. J Physiol 533, 165-173.
79. 2+-exchanger in normal and detubulated rat cardiomyocytes. J Mol Cell Cardiol 35, 1325-1337.
80. 2+. J Gen Physiol 109, 361-369.
81. Trafford AW, Díaz ME & Eisner DA (1999). A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes. Pflugers Arch 437, 501-503.
82. Trafford AW, Diaz ME, O'Neill SC & Eisner DA (1995). Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes. J Physiol 488, 577-586.
83. Urbanczyk J, Chernysh O, Condrescu M & Reeves JP (2006). Sodium-calcium exchange does not require allosteric calcium activation at high cytosolic sodium concentrations. J Physiol 575, 693-705.
84. Venetucci LA, Trafford AW, O'Neill SC & Eisner DA (2007). Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart. Ann N Y Acad Sci 1099, 315-325.
85. 2+ exchanger in normal and failing rat heart. J Physiol 567, 493-504.
86. 2+ exchange current. Circ Res 92, 950-952.
87. Weber CR, Ginsburg KS, Philipson KD, Shannon TR & Bers DM (2001). Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes. J Gen Physiol 117, 119-131.
88. Weber CR, Piacentino V III, Ginsburg KS, Houser SR & Bers DM (2002). Na/Ca exchange current and submembrane [Ca] during the cardiac action potential. Circ Res 90, 182-189.