A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

Journal of Hepatology

Volumn 58, Issue 5, 2013, Pages 875-882

  Urabe, Yuji ^a,b   Ochi, Hidenori ^b   Kato, Naoya ^a   Kumar, Vinod ^a,c   Takahashi, Atsushi ^c   Muroyama, Ryosuke ^a   Hosono, Naoya ^c   Otsuka, Motoyuki ^d   Tateishi, Ryosuke ^d   Lo, Paulisally Hau Yi ^a   Tanikawa, Chizu ^a   Omata, Masao ^d   Koike, Kazuhiko ^d   Miki, Daiki ^b   Abe, Hiromi ^b   Kamatani, Naoyuki ^c   Toyota, Joji ^e   Kumada, Hiromitsu ^f   Kubo, Michiaki ^c   Chayama, Kazuaki ^b   Nakamura, Yusuke ^a,c   Matsuda, Koichi ^a   more..

^a UNIVERSITY OF TOKYO   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e Sapporo Kosei General Hospital   (Japan)

^f TORANOMON HOSPITAL   (Japan)

Author keywords

Genome wide association study; Hepatitis C virus; Liver cirrhosis; Major histocompatibility complex

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; GENOMIC DNA; PROTHROMBIN;

ADULT; AGED; ALLELE; ARTICLE; CHROMOSOME 6P; CHROMOSOME ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; JAPANESE; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POPULATION RESEARCH; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; THROMBOCYTE;

ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HEPACIVIRUS; HEPATITIS C; HLA-DQ ALPHA-CHAINS; HLA-DRB1 CHAINS; HUMANS; JAPAN; LIVER CIRRHOSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84876282366     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.12.024     Document Type: Article

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