Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility

Journal of Human Genetics

Volumn 56, Issue 6, 2011, Pages 436-439

  Kumar, Vinod ^a,b   Matsuo, Keitaro ^c   Takahashi, Atsushi ^b   Hosono, Naoya ^b   Tsunoda, Tatsuhiko ^b   Kamatani, Naoyuki ^b   Kong, Sun Young ^d   Nakagawa, Hidewaki ^b   Cui, Ri ^a   Tanikawa, Chizu ^a   Seto, Masao ^c   Morishima, Yasuo ^c   Kubo, Michiaki ^b   Nakamura, Yusuke ^a,b   Matsuda, Koichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b RIKEN   (Japan)

^c AICHI CANCER CENTER HOSPITAL   (Japan)

^d National Cancer Center   (South Korea)

Author keywords

13q12; 14q32; Association study; DLBCL; lymphoma

Indexed keywords

ARTICLE; CDC42BPB GENE; CHROMOSOME 13Q; CHROMOSOME 14Q; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; INTRON; JAPANESE; LARGE CELL LYMPHOMA; LNX 2 GENE; MAJOR CLINICAL STUDY; MOLECULAR PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 14; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-TYROSINE KINASES;

EID: 79959654413     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2011.35     Document Type: Article

References (25)

1. Coiffier, B. Immunochemotherapy: The new standard in aggressive non-Hodgkin's lymphoma in the elderly. Semin. Oncol. 30, 21-27 (2003). (Pubitemid 36337348)
2. Izumo, T., Maseki, N., Mori, S. & Tsuchiya, E. Practical utility of the revised European- American classification of lymphoid neoplasms for Japanese non-Hodgkin's lymphomas. Jpn. J. Cancer Res. 91, 351-360 (2000). (Pubitemid 30198177)
3. Coiffier, B., Lepage, E., Briere, J., Herbrecht, R., Tilly, H., Bouabdallah, R. et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N. Engl. J. Med. 346, 235-242 (2002). (Pubitemid 34438862)
4. Altieri, A., Bermejo, J. L. & Hemminki, K. Familial risk for non-Hodgkin lymphoma and other lymphoproliferative malignancies by histopathologic subtype: The Swedish Family-Cancer Database. Blood 106, 668-672 (2005). (Pubitemid 40984007)
5. Lech-Maranda, E., Baseggio, L., Bienvenu, J., Charlot, C., Berger, F., Rigal, D. et al. Interleukin-10 gene promoter polymorphisms influence the clinical outcome of diffuse large B-cell lymphoma. Blood 103, 3529-3534 (2004). (Pubitemid 38525688)
6. Habermann, T. M., Wang, S. S., Maurer, M. J., Morton, L. M., Lynch, C. F., Ansell, S. M. et al. Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era. Blood 112, 2694-2702 (2008).
7. Goldin, L. R., Bjorkholm, M., Kristinsson, S. Y., Turesson, I. & Landgren, O. Highly increased familial risks for specific lymphoma subtypes. Br. J. Haematol. 146, 91-94 (2009).
8. Nakamura, Y. The BioBank Japan project. Clin. Adv. Hematol. Oncol. 5, 696-697 (2007). (Pubitemid 351699412)
9. Matsuo, K., Hamajima, N., Suzuki, R., Ogura, M., Kagami, Y., Taji, H. et al. Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma. Am. J. Hematol. 77, 351-357 (2004). (Pubitemid 39578315)
10. Ohnishi, Y., Tanaka, T., Ozaki, K., Yamada, R., Suzuki, H. & Nakamura, Y. A highthroughput SNP typing system for genome-wide association studies. J. Hum. Genet.46, 471-477 (2001). (Pubitemid 32744120)
11. Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A., Bender, D. et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007). (Pubitemid 47330214)
12. Barrett, J., Fry, B., Maller, J. & Daly, M. J. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265 (2005). (Pubitemid 40202029)
13. Ge, D., Zhang, K., Need, A. C., Martin, O., Fellay, J., Urban, T. J. et al. WGAViewer: Software for genomic annotation of whole genome association studies. Genome Res.18, 640-643 (2008). (Pubitemid 351482788)
14. Yuan, H. Y., Chiou, J., Tseng, W., Liu, C. H., Liu, C. K., Lin, Y. J. et al. FASTSNP: An always up-to-date and extendable service for SNP function analysis and prioritization. Nucleic Acids Res. 34, W635-W641 (2006). (Pubitemid 44529848)
15. Nie, J., McGill, M. A., Dermer, M., Dho, S. E., Wolting, C. D. & McGlade, C. J. LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation. EMBO J. 21, 93-102 (2002). (Pubitemid 34087078)
16. Leong, K. G. & Karsan, A. Recent insights into the role of Notch signaling in tumorigenesis. Blood 107, 2223-2233 (2006). (Pubitemid 43345539)
17. Chiaramonte, R. Still puzzling Notch signaling in B-cell malignancies. Leuk. Res. 30, 1331-1332 (2006). (Pubitemid 44307332)
18. Leung, T., Chen, X. Q., Tan, I., Manser, E. & Lim, L. Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization. Mol. Cell. Biol. 18, 130-140 (1998). (Pubitemid 28021025)
19. Choi, S. H., Czifra, G., Kedei, N., Lewin, N. E., Lazar, J., Pu, Y. et al. Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta. J. Biol. Chem. 283, 10543-10549 (2008).
20. Cigudosa, J. C., Parsa, N. Z., Louie, D. C., Filippa, D. A., Jhanwar, S. C., Johansson, B. et al. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas. Genes Chromosomes Cancer 25, 123-133 (1999). (Pubitemid 29226595)
21. Skibola, C. F., Bracci, P. M., Halperin, E., Conde, L., Craig, D. W., Agana, L. et al. Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma. Nat. Genet. 41, 873-875 (2009).
22. Yamaguchi-Kabata, Y., Nakazono, K., Takahashi, A., Saito, S., Hosono, N., Kubo, M. et al. Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: Effects on population-based association studies. Am. J. Hum. Genet. 83, 445-456 (2008).
23. Gurbuxani, S., Anastasi, J. & Hyjek, E. Diffuse large B-cell lymphoma-more than a diffuse collection of large B cells: An entity in search of a meaningful classification. Arch. Pathol. Lab. Med. 133, 1121-1134 (2009).
24. Hans, C P., Weisenburger, D. D., Greiner, T. C., Gascoyne, R. D., Delabie, J., Ott, G. et al. Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood 103, 275-282 (2004). (Pubitemid 38029949)
25. Lenz, G., Wright, G., Dave, S. S., Xiao, W., Powell, J., Zhao, H. et al. Stromal gene signatures in large-B-cell lymphomas. N. Engl. J. Med. 359, 2313-2323 (2008).