Neural and behavioral effects of a novel Mu opioid receptor antagonist in binge-eating obese people

Biological Psychiatry

Volumn 73, Issue 9, 2013, Pages 887-894

  Cambridge, Victoria C ^a   Ziauddeen, Hisham ^a,b,d,e   Nathan, Pradeep J ^a,b   Subramaniam, Naresh ^a   Dodds, Chris ^b   Chamberlain, Samuel R ^a,b,e   Koch, Annelize ^b   Maltby, Kay ^b   Skeggs, Andrew L ^b   Napolitano, Antonella ^b   Farooqi, I Sadaf ^d   Bullmore, Edward T ^a,b,c,e   Fletcher, Paul C ^a,e  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Binge eating; fMRI; hedonics; motivation; obesity; opioid

Indexed keywords

GSK 1521498; MU OPIATE RECEPTOR ANTAGONIST; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BINGE EATING DISORDER; CALORIC INTAKE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GLOBUS PALLIDUS; GRIP STRENGTH; HUMAN; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; MOTIVATION; NEUROMODULATION; OBESITY; PRIORITY JOURNAL; PUTAMEN; TASK PERFORMANCE;

ADOLESCENT; ADULT; BINGE-EATING DISORDER; BRAIN; BRAIN MAPPING; DOUBLE-BLIND METHOD; FEEDING BEHAVIOR; FEMALE; FUNCTIONAL NEUROIMAGING; HUMANS; INDANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MOTIVATION; NARCOTIC ANTAGONISTS; OBESITY; RECEPTORS, OPIOID, MU; TRIAZOLES;

EID: 84876274229     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.10.022     Document Type: Article

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