Inhibition of opioid transmission at the μ-opioid receptor prevents both food seeking and binge-like eating

Neuropsychopharmacology

Volumn 37, Issue 12, 2012, Pages 2643-2652

  Giuliano, Chiara ^a   Robbins, Trevor W ^a   Nathan, Pradeep J ^b,c   Bullmore, Edward T ^a,b,c   Everitt, Barry J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

binge eating disorder; conditioned stimulus; food seeking; m opioid receptor antagonist; naltrexone; obesity

Indexed keywords

GSK 1521498; MU OPIATE RECEPTOR ANTAGONIST; NALTREXONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINGE EATING DISORDER; CACAO; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; EATING DISORDER; FEMALE; FOOD INTAKE; FOOD SEEKING EATING DISORDER; HYPERPHAGIA; HYPOPHAGIA; MALE; MOTIVATION; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

ANIMALS; AVOIDANCE LEARNING; BINGE-EATING DISORDER; CONDITIONING, OPERANT; FEEDING BEHAVIOR; FEMALE; FOOD PREFERENCES; INDANS; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; RATS; RECEPTORS, OPIOID, MU; REINFORCEMENT SCHEDULE; SYNAPTIC TRANSMISSION; TRIAZOLES;

EID: 84867577607     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.128     Document Type: Article

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